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Tag: "plaque" at biology news

Neuronal 'traffic jam' marks early Alzheimer's disease

...of Alzheimer's disease early in their life, before plaque formation, to see if we could detect early evidenc...ly in the life of those animals -- well before any plaque deposition -- were obvious axonal defects," said Goldstein. "We saw large swellings in their axons. ...

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

...nt, Holtzman and some other scientists hadregarded plaque damage to nerve cells as a fait accompli--somethin... cellbranches.To correlate brain cell changes with plaque development, Brendzainjected another dye, developed by scientists at the University ofPittsburgh, th...

Key molecule in plant photo-protection identified

...nt, Holtzman and some other scientists hadregarded plaque damage to nerve cells as a fait accompli--somethin... cellbranches.To correlate brain cell changes with plaque development, Brendzainjected another dye, developed by scientists at the University ofPittsburgh, th...

Gene vaccine for Alzheimer's disease shows promising results

...d protein vaccination had shown someslowing in the plaque buildup, negative side effects also occurred in ahandful of patients. Some had autoimmune responses that causedencephalitis.The key in the UT Southwestern study was finding another way tovaccinate patients without stimulating the body's own immune cy...

Scientists identify molecular events that drive cell senescence

...d protein vaccination had shown someslowing in the plaque buildup, negative side effects also occurred in ahandful of patients. Some had autoimmune responses that causedencephalitis.The key in the UT Southwestern study was finding another way tovaccinate patients without stimulating the body's own immune cy...

Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease

... they said, could lead to approaches to preventing plaque formation. The researchers led by Boris Akhremitchev are using the infinitesimal tip of a customized atomic force microscope (AFM) to capture, isolate and study single molecules, called monomers, that are the building blocks of the toxic protein pol...

Molecule that usually protects infection-fighting cells may cause plaque deposits inside arteries

... normal AIM function, there was marked presence of plaque deposits in the arteries following a diet of high-... an artery and gradually thicken into a plaque. As plaque grows, it narrows the artery more and more. When the plaque ruptures, blood clots form that can bloc...

To control germs, scientists deploy tiny agents provocateurs

...ealth. Biofilms form the green slime on rocks, the plaque on human teeth and the slippery film on ship hulls. If a single cell were analogous to one man, biofilms would be the "bacterial equivalent of mob mentality," says Blackwell. In the realm of health, biofilms are at the root of growing numbers of ten...

Nano-bumps could help repair clogged blood vessels

...m open during or after surgery to remove dangerous plaque deposits from the vessels. The stents, which are m... arteries to grow new tissue after vessel-clogging plaque deposits have been removed. A major problem, however, is that the body often perceives the metal dev...

Research on antibiotics receives historical recognition

...f the Society, will present a commemorative bronze plaque to Tim Casey, Ph.D., Dean of Academic and Student Programs at Cook College, Rutgers University. H. Boyd Woodruff, Ph.D., who isolated the first two actinomycete antibiotics, will be the featured speaker. The award presentation takes place in conjunct...

Pinpointing a culprit molecule in Alzheimer's disease

...d beta (Ab) peptide that clusters into the amyloid plaque that clogs the brain and kills brain cells. The c...Ab42 mice showed extensive accumulation of amyloid plaque and resulting neural damage. What's more, when the researchers crossed the Ab42 mice with those prod...

U of MN researchers reverse memory loss in mice

...neurons, and amyloid deposits, a toxic build-up of plaque in the brain. The researchers found that even after the memory loss was regained in the mice, the tangles remained, and even increased in number. This suggests that the tangles are not a cause of dementia as previously thought. The mice serve as a m...

Unweaving amyloid fibers to solve prion puzzles

Amyloid fibers are best known as the plaque that gunks up neurons in people with neurodegenerative illnesses such as Alzheimer's and Creutzfeldt-Jacob disease--the human analog of mad cow disease. But even though amyloids are common and implicated in a host of conditions, researchers haven't b...

Variant prion protein causes infection but no symptoms

...ficant. Second, the dense accumulations of scrapie plaque in the brain resembled the plaque seen in Alzheimer's, but it wasn't toxic," which might support more recent concepts about plaque in ...

Old drug shows new promise for Huntington's Disease

...n, it interferes with the creation of beta-amyloid plaque in the brain, which has been implicated in the progression of Alzheimer's symptoms. Currently, Clioquinol is banned for internal use in many countries because of its side effects. In Japan in the late 1950s and 60s, the drug was found to cause a neu...

Give thanks for the cranberry, say dental researchers

...ymes known as glucosyltransferases to build dental plaque piece by piece, quickly forming a gunky fortress t...hat cranberry juice prevents bacteria from forming plaque by inhibiting those enzymes and by stopping additional bacteria from glomming on to the ever-growing...

Researchers show how air pollution can cause heart disease

...he whole, mice breathing polluted air had far more plaque than those breathing filtered air. In cross sectio...holesterol levels, which are thought to exacerbate plaque buildup. Though findings for increased plaque among mice eating normal diets were not statisticall...

Researchers discover a new genetic cause of Alzheimer's disease

...rching diligently for ways to treat it. Amyloid plaque formation plays a key role Genetic research has previously shown a direct connection between amyloid protein and the development of senile plaques and loss of cells. Amyloid protein originates when it is cut by enzymes from a larger precursor protei...

The urban evolution lab

...rching diligently for ways to treat it. Amyloid plaque formation plays a key role Genetic research has previously shown a direct connection between amyloid protein and the development of senile plaques and loss of cells. Amyloid protein originates when it is cut by enzymes from a larger precursor protei...

Intensive statin therapy may partially reverse plaque build-up in arteries

...rug can regress (partially reverse) the buildup of plaque in the coronary arteries. This finding has neve...ogression of coronary atherosclerosis, or arterial plaque build-up, but not actually reduce disease burden. ACC.06 is the premier cardiovascular medical meeti...

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