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Tag: "placebo" at biology news

Bypassing eggs, flu vaccine grown in insect cells shows promise

...er dose (135 micrograms), and one-third received a placebo shot that didn’t include vaccine. Each of the “real?shots included vaccine designed to protect against the three strains of flu that had been predicted to be the greatest threat during the 2004-2005 winter, when the study was conducted. As the sci...

NIAID DNA vaccine for H5N1 avian influenza enters human trial

...etween the ages of 18 and 60. Fifteen will receive placebo injections and 30 will receive three injections of the investigational vaccine over 2 months and will be followed for 1 year. Volunteers will not be exposed to influenza virus. The vaccine contains no infectious material, and the virus was not pre...

Africa's first large-scale HIV vaccine study launches

...he trial design will compare the test vaccine to a placebo (a harmless substance) and, to eliminate bias, neither volunteers nor researchers will know who receives the vaccine and who receives the placebo. The trial will last about four years. The trial has been approved by the South African Medicines Contro...

Insomnia drug can improve brain function

...l of these were conducted with both zolpidem and a placebo in a randomized, double-blind study. The results showed that after receiving zolpidem, the patient was able to stand up and walk, repeat words and sentences, read words, and name objects, although she was not able to speak spontaneously. Administr...

UW launches study testing adult stem cells for heart damage repair

...ician knows if he received his own stem cells or a placebo substance. This trial is the first human Phase I...l catheter system to deliver either CD34+ cells or placebo into areas of the heart that have poor blood flow. Subjects are randomly selected to receive either ...

Lead-'scrubbing' drug may also improve muscle function in lead-exposed children

...ild—then 5 years old—had completed the succimer or placebo therapy. Tests were designed to eliminate or challenge factors that help maintain postural balance, such as eyesight and visual context. “Our statistical analysis revealed that subjects who received succimer therapy showed a significant improve...

Protein therapy may reduce infarct size in heart attack patients

...injections of the active study drug (KAI-9803) vs. placebo in four dose groups (0.05, 0.5, 1.25 or 5.0 mg of KAI-9803). Researchers performed tests to assess heart function at various time points and assessed safety and cardiac outcomes through six months. This trial was designed as an exploratory study to...

Stem cell therapy shows promise in regenerating damaged muscle in heart attack patients

...rhythmic adverse event compared to those receiving placebo (9 % vs. 37%, p=0.025) and significantly more pati...ition at six months as compared to those receiving placebo (42% vs. 11%, p=0.027). Provacel is a preparation of adult stem cells pre-formulated for intraven...

Monoclonal antibody reduces exacerbations in asthmatics

...is factor alpha (TNFá). Eighteen patients received placebo during the eight-week double-blind study. Accordi...ness." During the study, 13 of the 18 patients on placebo (72 percent) experienced exacerbations, as compared to only four out of 14 patients (29 percent) on ...

Negative effects of caffeine are stronger on daytime sleep than on nocturnal sleep

...nsumers participated in both caffeine (200 mg) and placebo (lactose) conditions in a double-blind crossover design. Seventeen subjects followed their habitual sleep–wake cycle and slept in the laboratory during the night (Night), while 17 subjects were sleep deprived for one night and recovery sleep started ...

New brain-chemistry differences found in depressed women

...used to see how the brain responds to pain ?and to placebo pain treatment. The technique uses a form of a drug called carfentanil, which binds to the same receptors on the surface of brain cells that brain chemicals called mu-opioids bind to. Mu-opioids, sometimes also called endorphins, reduce or block ...

New study finds chocolate chip cookies lower cholesterol

...ssigned to the Right Direction Cookie group or the placebo cookie group. Two cookies per day were consumed for four weeks. After a three week washout period, subjects received the other cookies for an additional four weeks. At the end of each treatment period, two blood samples were drawn on different days (...

Transplanted brain cells hold promise for Parkinson's disease

... study, researchers compared animals that received placebo treatment with those that received only protective neurotrophic factors secreted by stem cells and those that had a transplant. Animals that received transplants essentially regained control of their movement, placebo-treated animals did not recov...

Study of gene transfer for erectile dysfunction shows promise

...udy that includes a "control" group treated with a placebo is needed to confirm the safety and effectiveness of the treatment. Other researchers on the project were Melman, Natan Bar-Chama, M.D., with Mount Sinai School of Medicine, Andrew McCullough, M.D., with New York University School of Medicine, an...

Melatonin improves mood in winter depression

... to bright light, however, there is a considerable placebo response associated with it. Melatonin can also ca... patients to one of three treatment groups, taking placebo capsules or melatonin in the morning or afternoon for three weeks. After four years of study, they c...

Herbal medicine silymarin may help sugar-control in people with type II diabetes

...ay for 4 months, while the remaining 26 received a placebo treatment. All of the patients continued to use conventional oral hypoglycaemic treatment during the trial. Patients were examined at monthly intervals. Compared with the beginning of the trial, the treatment group had a significant reduction in f...

Trials for new drug to overcome HIV

...egimes are failing will receive either PA-457 or a placebo in addition to their standard drugs. There are plans to try the drug along with new regimes tailored to individual patients, though Allaway warns that larger trials are needed and PA-457 will not reach the market until 2009 at the earliest. Other HI...

Hopkins scientists show hallucinogen in mushrooms creates universal 'mystical' experience

...g or life satisfaction compared with those given a placebo at the same test session. A majority said their mo...t the expectations of getting the test drug or the placebo would influence subjects' perceptions. To lessen the former, each subject met several times, befo...

Gene therapy injected into the brains' of mice with Huntington's disease

...herapy. A second control group was injected with a placebo gene therapy. The third group received the active GDNF gene therapy. To measure fine motor coordination, balance and fatigue, researchers evaluated mice walking on a rotating rod. Mice injected with the gene therapy performed significantly better ...

Natural pine bark extract relieves muscle cramp and pain in athletes and diabetics

...ycnogenol. Results indicated participants who took placebo experienced no decrease in pain. Cramps are a common problem for people of all ages, ranging to the extreme fit and healthy to people who suffer from health problems. Previously, magnesium was hailed as the natural approach for relieving muscle cra...

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