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Tag: "pivotal" at biology news

Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism

...nstitute G. Gaslini in Genova, Italy, confirms the pivotal role played by Cytomegalovirus infection in the pa...on and high cholesterol levels are known to play a pivotal role in the pathogenesis of the disease that also recognises a genetic influence. However, it is wel...

Row over study puts Korea's scientific community under scrutiny again

...nt. He explained how "our institution will serve a pivotal role in restoring the severely damaged reputation and credibility of stem cell and life science research in Korea after the Hwang scandal." Professor Kim's intervention leaves little doubt about how seriously the CHA group views the potential of t...

Scripps research study shows humans and plants share common regulatory pathway

...milarities between the Nod1 protein, which plays a pivotal role in the innate immune system’s recognition and response to bacterial infection and members of the R protein family. "There has been a great deal of speculation that R proteins and Nod1 are related, but our study provides the first direct link...

New player in commitment to life as a fat cell

Researchers have discovered a pivotal new player in early events that commit fat cell precursors to becoming full-blown fat, according to a report in the February issue of the journal Cell Metabolism, published by Cell Press. Drugs that block some activities of the enzyme, known as xanth...

Common gene version optimizes thinking -- but with a possible downside

...ns by Greengard's team that ultimately linked this pivotal protein to depression and substance abuse as well as to schizophrenia," added NIMH Director Thomas Insel, M.D. To understand DARPP-32's role in the human brain, the NIMH researchers used genetic, structural and functional magnetic resonance imagi...

Darwin's famous finches and Venter's marine microbes

Although the Galápagos finches were to play a pivotal role in the inception of Darwin’s theory of evolution through natural selection, he had no inkling of their significance when he collected them during his voyage on the HMS Beagle. Similarly, it is hard to predict the impact the vast amount of mari...

New research shows that flu is a trigger of heart attacks

...these lesions grow over time. Inflammation plays a pivotal role in development and growth of these lesions. Most people in Western countries live with different stages of atherosclerosis and many will never show any clinical manifestations of the atherosclerosis. However, in some patients the quiescent, stab...

Temple University Hospital investigates treatment for cervical dysplasia

...HARMA, Inc. that is currently being evaluated in a pivotal phase 2 clinical program in multiple centers in the U.S., including Philadelphia. "This product candidate is designed to enhance the body's immune response to cervical dysplasia, and is being developed to offer patients with cervical dysplasia and he...

Recycling technology

Scientists at the University of York are to play a pivotal role in new research aimed at averting a growing environmental problem caused by discarded liquid crystal displays (LCDs). LCDs are a fixture of modern life, appearing in everything from pocket calculators and mobile telephones to wide-screen telev...

Researchers barcode DNA of Venice museum's vast fungi collection

..." said Garbelotto. "This provides governments with pivotal information needed to avoid repeated introductions of pathogens." Garbelotto is working with Italian mycologist Giovanni Robich and Luca Mizzan, curator of Marine Biology at the Venice Museum of Natural History, to sort through the samples in the ...

West Australian fossil find rewrites land mammal evolution

...ay in the journal Nature. "Gogonasus is the new pivotal fossil for understanding the earliest phase in the transition from sea-going fish to land-dwelling tetrapods - from dinosaurs, to kangaroos, and ultimately, us humans,'' Mr Fitzgerald said. "The fossils of Gogonasus raise the possibility that tetr...

Zinc plays important role in brain circuitry

...e that "The data presented in our paper disclose a pivotal role of ambient synaptic [zinc ion] for glycinergic neurotransmission in the context of normal animal behavior." They also concluded that their results implied that manipulating synaptic zinc levels could affect the neuronal action of zinc, but that ...

Researchers find that bumblebees' flower choice matters

...e professor of Biological Sciences. The bees are pivotal players in determining which plant populations survive through successful reproduction. If scientists could better understand nature's decision-making process, then they could use the information to increase crop yields and to boost conservation of n...

Fly's courtship sheds light on the formation of innate behaviors

...erience. One gene, fruitless, has been shown to be pivotal to the emergence of these stereotypical behaviours. Fruitless is known to generate a variety of similar but functionally different proteins, some of which are exclusively expressed in male flies. Using a mutant that specifically disrupts one form of...

Structure determined for p53 tumor suppressor protein as bound to DNA for anti-cancer activity

...ointing to this region of the p53 protein as being pivotal to its anti-cancer activity. Clearly, a detailed view of the p53 protein in direct contact with DNA could provide important insights into preventing and treating an array of human cancers. To date, however, despite having learned a good deal about ...

With few factors, adult cells take on character of embryonic stem cells

...ntenance of embryonic stem cell identity also play pivotal roles in the induction of pluripotency" in other body cells, he explained. The researchers selected 24 genes--all previously found to play a role in early embryos and embryonic stem cell identity--as candidate factors that might give body cells th...

HIV infection requires an accomplice: B cells with special protein direct HIV to T cells

...lls themselves do not become infected, they play a pivotal role as an accomplice in HIV's takeover of T cells. According to the research to be reported by Giovanna Rappocciolo, Ph.D., research assistant professor of infectious diseases and microbiology at GSPH, laboratory studies provide evidence of DC-SI...

FSU biologists uncover mechanisms that shape cells for better or worse

... of the oocyte," Deng said. "That knowledge adds a pivotal link to our understanding of precisely how cell-to-cell communication occurs in this model system." In recognition of groundbreaking work to-date by the FSU scientists -- and to further the understanding of the mechanisms involved in cell-cell comm...

With few factors, adult cells take on character of embryonic stem cells

...ntenance of embryonic stem cell identity also play pivotal roles in the induction of pluripotency" in other body cells, he explained. The researchers selected 24 genes--all previously found to play a role in early embryos and embryonic stem cell identity--as candidate factors that might give body cells th...

Queensland scientists identify molecule that links both sides of the brain

...a variety of molecular guidance systems which play pivotal roles in the guidance of nerve fibres and newly born neurons throughout the developing central nervous system. ...

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