Immune system has evolved to prevent autoimmune disease
...ior at the molecular or atomic scale to build up a picture of the behavior at a larger level. In this case, Deem and postdoctoral researchers Jun Sun and David J. Earl studied the physical properties of fragments of DNA to determine the origins, behavior, and generation of antibodies. Generating antibodies ...Skull study sheds light on dinosaur diversity
...ound plenty of other titanosaur bones, providing a picture of a group of sauropods with specialized limb bone...lists finally can start piecing together a clearer picture of the dinosaurs' lives. One feature of the skulls is particularly intriguing. "They have elongate...Computers close in on protein structure prediction
...rm the protein backbone. The computer adds a fuzzy picture of the protruding side chains that give each amino...istance. In stage two, Rosetta replaces the fuzzy picture of the side chains with detailed, physically realistic models with all the atoms represented. From t...Unweaving amyloid fibers to solve prion puzzles
...zle of how amyloids form. "We now have an overall picture of how prions join together to form the amyloid's molecular structure," says Lindquist, who also is a professor of biology at MIT. Prions are in the business of converting other prion molecules to join their ranks. And as they join together, they ca...When in danger humans are similar to a deer in the headlights
...imals, freeze when encountering a threat. The mere picture of an injured or mutilated human induces this reaction. When viewing these unpleasant images, the study's participants froze as their heart rate decelerated and amount of their body sway reduced. The authors found that this abrupt reaction, so critic...Defect in gene causes 'neuralgic amyotrophy'
...called the Parsonage-Turner Syndrome. The clinical picture of this more frequently occurring form - 2 to 4 cases per 100,000 persons - is not distinguishable from that of the heritable form. The attacks of pain are usually provoked by external factors such as vaccination, infection, operation, and even pre......jnowski. "So, we will continue to develop this new picture of the synapse to convince doubters, because this is such a different way of looking at how the synapse functions." Sejnowski said that he and his collaborators will extend their study to other types of synapses that are more complex and difficult to...HIV Therapy Greatly Extends Life of Key T Cells, Scientists Find
...trials currently underway should provide a clearer picture of the clinical impact of IL-2 on the course of HIV disease and its potential role in the management of HIV-infected patients, he adds. Information on these and other HIV clinical trials is available at www.aidsinfo.nih.gov. Other authors on the pap...Fundamental discovery -- Bone fracture
...ticles and on collagen fibrils," said Hansma. "The picture of bone was that it consisted of these collagen fibrils coated with tiny mineral crystals only a few atoms thick. What we found is that there is a glue in bone that holds these mineralized collagen fibrils together, and this glue works along the same...Micro-molecule plays big role in birth defects
...Genetics Institute were able to get the first-ever picture of how limbs would develop in a vertebrate without the help of microRNAs. When microRNAs were not available to turn off certain genes, the mice grew malformed, nonfunctional limbs. The finding may provide insight into human birth defects, but scient...Pinpointing the cause of a neurodegenerative disorder
...eration, just like humans with SCA1. "The overall picture we have now is that glutamine expansion causes some aspects of the pathology of SCA1 in part by enhancing the activity of the domain that is outside the glutamine repeat," said Zoghbi. The finding offers insight into the molecular mechanisms that ca...New tool reveals secrets of migrating cells
...imensional data - spatial and time data - to get a picture of long-range cell migrations through tissue," said immunologist Ellen Robey, professor of immunology at the University of California, Berkeley. "The ability to directly visualize cells in living tissues has changed the way immunologists think about ...International Team Determines Geographic Origin of Leprosy
...organism, in this case M. leprae, and to develop a picture of how leprosy spread from its point of origin. The team looked for SNPs in 171 clinical specimens of M. leprae taken from people infected with the bacterium. The specimens came from 21 countries representing five continents. Four types of SNP appea...Deep thinking: Scientists sequence a cold-loving marine microbe
...loving organism. Together, these analyses offer a picture of evolution in action, as C. psychrerythraea uses subtle tweaks in common bacterial biology to adapt to its chilly environs. For instance, the bacterium taps a group of four to five genes to generate polyunsaturated fatty acids and pack those acids ...Bioinformatics reveals new gene regulation system
... providing additional evidence that the regulatory picture drawn by the team was correct. Israeli researchers simultaneously showed through 'wet' biology experiments in Streptomyces bacteria that a transcription factor from this family represses Nrd gene expression in the living bacterial cell, confirming t...Agilent Technologies introduces high-capacity human protein removal system for proteomics research
...il 25 million years later than people thought, the picture of dinosaur evolution radically shifts. "Basically, you have two groups that were thought to appear at the same time and co-evolve, and now you have one completely wiped away," Parker said. "So where did the ornithischian dinosaurs come from? We don...Revueltosaurus skeleton unearthed at Petrified Forest upsets dinosaur tale
...il 25 million years later than people thought, the picture of dinosaur evolution radically shifts. "Basically, you have two groups that were thought to appear at the same time and co-evolve, and now you have one completely wiped away," Parker said. "So where did the ornithischian dinosaurs come from? We don...Scientists discover odd-ball rodent
Editor : Sadly, no picture available yet, but there's a recent wiki article with more details . New family of mammals? Wow! Is it a squirrel? A rat? A Guinea pig? Try none of the above. A team of scientists working in Southeast Asia have discovered a long-whiskered rodent ...New understanding of cell movement may yield ways to brake cancer's spread
...hers are looking at developing a three-dimensional picture of PIP3 -binding domain's molecular structure. "We are currently planning these structure studies with our collaborators here at the Burnham," Vuori said. "If we know its molecular structure, we hope to be able to make small chemicals that inhibit in...Hopkins AIDS experts issue warning about global efforts to provide drug therapies
...outcry led Life magazine to feature on its cover a picture of a child rejected for treatment, prompting the committee to attempt to change its criteria toward a psychological assessment. With liver transplants, patient selection was plagued by different interpretations of who medically benefited most from a...