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Tag: "photoreceptor" at biology news

'Lucky 13' as new gene discovery offers further hope for childhood blindness

...ina. Protein transport is essential within retinal photoreceptor cells as they are long, thin cells with a highly evolved structure on one end (the outer segment) which detects light and sends signals to the brain, a function requiring a large amount of energy. "LCA is usually a disease where protein function h...

Making mice with enhanced color vision

...he first ancestral primate inherited a new type of photoreceptor more than 40 million years ago, it probably experi...ce could discriminate among the lights. "Each photoreceptor absorbs a range of wavelengths, but the efficiency changes with wavelength," Nathans explains. "For ...

Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration

... The team of scientists found that transplanted photoreceptor precursor cells survived and became integrated int...cus on characterizing the mechanisms that generate photoreceptor precursors from stem cells. Swaroop believes the research has potential for developing therapies fo...

Does missing gene point to nocturnal existence for early mammals?

...iversity of Manchester. "But, recently, a third photoreceptor was discovered that is activated by a gene called melanopsin. This melanopsin photoreceptor is not linked to sight but uses light for non-visual processes, such as regulating our day-night rhy...

Light-sensitive photoswitches could restore sight to those with macular degeneration

...to light in the eyes of people who have lost their photoreceptor cells, in particular, the rods and cones in the most sensitive part of the retina," Isacoff said. "We plan to develop the tools to create a new layer of optically active cells for the retina." Loss of photoreceptors - the light detectors in the ret...

UF scientists restore sight to chickens with blinding disease

...indness. "We were able to restore function to the photoreceptor cells in the retinas of an avian model of a diseas...ion and function best in daylight. The predominant photoreceptor cell type in the chicken retina, the cone cell, is the same cell type that is essential for normal h...

New fruit fly protein illuminates circadian response to light

...g flies. When a fruit fly is exposed to light, a photoreceptor called cryptochrome (CRY) transduces the light signal and kicks off a series of reactions within the clock cells of the brain. Under normal conditions, CRY will respond to light by binding to a protein called timeless (TIM). A second protein, a membe...

'Prosthetic' retinal cells let blind mice see light

...o "inner retinal neurons" in a strain of mice with photoreceptor deficiency that resembles the defect in such inher...e remodeling of inner retinal neurons triggered by photoreceptor degeneration has raised some concerns for the retinal-based rescue strategy after the death of photo...

Lizard 'third eye' sheds light on evolution of color vision

...researchers propose that the lizard's parietal eye photoreceptor cells represent a "missing link" between the light...hese structures to obtain more clues about how our photoreceptor cells, the rods and cones, came about. As he says, he's most curious about how the same function can...

Behavioral studies show UV contributes to marsupial color vision

...lor vision based on three different types of color photoreceptor cones--but unlike primates, a component of marsupial color vision includes sensitivity to ultraviolet wavelengths. In the study, researchers employed behavioral tests to show that at least one type of marsupial uses its detection of UV light as par...

UC Berkeley researchers create a biologically-inspired artificial compound eye

...'s eye. While an insect's ommatidia each end in a photoreceptor cell that transmits a light signal to the creature's optic nerve, Lee plans to couple his team's ommatidia with CCD photodiodes, the light-capturing units used in digital cameras and camcorders. He also has plans to link them to spectroscopes for che...

Scientists map one of biology's critical light-sensing structures

...y to understanding the "nuts and bolts" of how the photoreceptor senses light and triggers a series of downstream events that control growth and development, according to Katrina Forest, the other senior member of the team and a UW-Madison professor of bacteriology. "There were some surprises," says Forest of the ...

Gene therapy works in mice to prevent blindness that strikes boys

..., but the treated eyes appeared healthy. The eye's photoreceptor cells - the rods and cones that help the brain process light and color - were spared from the disease and the connections between the layers of the retinas were intact. In addition, the protein appears capable of moving within the retina to its targ...

Migratory songbirds have a specialized night-vision brain area

...visually detect the earth's magnetic field through photoreceptor molecules, whose light-sensitivity is modulated by the field. The researchers published their findings May 23, 2005, in the early online edition of the Proceedings of the National Academy of Sciences. The collaboration was led by Henrik Mouritsen of...

Glow-in-the-dark zebrafish at UH hold keys to biological clocks

...al mechanisms of vertebrate circadian rhythmicity, photoreceptor cell and molecular biology, and neurobiology. He is a member of the Society for Research on Biological Rhythms and the Society for Neuroscience and is currently funded under a $1.2 million National Institutes of Health grant through 2007 as the princ...

Ophthalmologists implant five patients with artificial silicon retina microchip

...into electrical signals within the retina. Loss of photoreceptor cells occurs in persons with retinitis pigmentosa ...tina seems a logical step in replacing the loss of photoreceptor cells of the retina. If the implant is tolerated well and is able to successfully stimulate the reti...

Ophthalmologists Use Artificial Silicon Retina Microchip To Treat Vision Loss

...into electrical signals within the retina. Loss of photoreceptor cells occurs in persons with retinitis pigmentosa ...tina seems a logical step in replacing the loss of photoreceptor cells of the retina. If the implant is tolerated well and is able to successfully stimulate the reti...

Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa

...a number of diseases that predominantly affect the photoreceptor layer or "light sensing" cells of the retina. Night blindness develops, usually in childhood, followed by loss of peripheral visual field, progressing over many years to tunnel vision and finally blindness. At Emory Eye Center retina specialists Tho...

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