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Tag: "phase" at biology news

Adult stem cell research at UB targets damaged hearts

...in future therapeutic applications." The second phase of the project will involve injecting the stem cells into swine with hibernating myocardium. The researchers will track the cells' progress, evaluate their feasibility, and determine if cells engineering for enhanced survival, blood vessel regenerat...

New research finds surveys of larval-stage organisms effective for measuring marine biodiversity

... has found that studying marine life in its larval phase with DNA barcoding is a valuable way to estimate b...iversity since most organisms have a developmental phase where minute larvae disperse on ocean currents. "For some groups of organisms, scientists can more...

Joslin discovers signs of residual islet cell function in people with long-term type 1 diabetes

...presented at the ADA meeting is part of the second phase of the Joslin 50-Year Medalist Study that is assessing these factors in 326 patients with more than 50 years of insulin-dependent diabetes. It evaluated a subset of 125 people with type 1 diabetes for biomarkers of insulin function. Of this group, 12...

Prion find points way to test for human 'mad cow' disease

...we have detected prions in what we call the silent phase of infection, which in humans can last up to 40 years," said Soto, senior author of the Science paper. "The concern is that if many people are incubating the disease silently, then secondary transmission from human to human by blood transfusion or s...

Eco-friendly bug sucker

...ethyl bromide. In 1997 160 governments promised to phase out its use by 2005 as part of the Montreal Protocol, but some exceptions were granted for the food and farming industries. "The initial hardware cost of an MSDD system is higher than methyl bromide, but the cost of chemicals is much cheaper, so tha...

Diabetes research takes wing thanks to long-lived fruit fly

... National Institutes of Health to conduct the next phase of their studies. Why spend such funds on a fly that lives 40 percent longer than the average fly? Because of its promise for human health. New findings on aging, diabetes, and stress converge on the fly the team created. Later this month Bohmann wi...

'Molecular assassin' targets disease gene

...blems such as eye disease and arthritis. The next phase in the therapy's development would be a trial, involving up to 10 people with non-melanoma skin cancers. The tumours would be injected with the drug over an eight-week period. "If such a trial were successful, it would be a significant development g...

NAU researchers chirping over discovery of new cricket genus

...y, Wynne explained. "We are still in the formative phase of characterizing the ecological communities of th...onent of the cave ecological inventory project and phase two of the Earth-Mars cave detection study. "Jut has a very diverse research program, one day he i...

Orange, grapefruit juice for breakfast builds bones in rats

...various human diseases. Limonoids will be the next phase of the study, but there are at least 40 different ones, Patil cautioned. "This study backs up our thoughts about the value of citrus," Patil said, noting that until researchers completely understand the interaction of grapefruit juice and certain me...

Study defines effective microbicide design for HIV/AIDS prevention

...or testing and five of them have reached the final phase of clinical trials. The Duke group's new model provides a "rational guide" for design specifications that could further improve such microbicides' ability to cut the rate of HIV spread, the researchers said. The researchers now are conducting studi...

Bacteria could make new library of cancer drugs that are too complex to create artificially

...odiginine analogue called GX15-070 is currently in phase 1 and 2 cancer treatment trials. However, analogues of other prodiginines, such as streptorubin B, could be even more powerful anti cancer tools, but they cannot currently be easily synthetically produced on a lab bench. Professor Greg Challis and...

Combination therapy shows promising results in patients with advanced lung cancer

An early phase study pairing an experimental targeted therapy wit...ncer patients. "I think the results of this early phase study are promising and I anticipate we'll have a better understanding of Tarceva resistance in the ...

Major cancer study aims to identify protein markers for early-stage disease

...se. The researchers will focus specifically on a phase in protein development known as "post-translational modifications," which occur after the code for a gene has been translated into a protein. Initially, the protein is a "naked scaffold," says Fisher, but over time it becomes decorated, much like a C...

With record resolution and sensitivity, tool images how life organizes in a cell membrane

...'short'' or ''tall'' chemical structures to create phase domains, or membrane features that they could study. Tall lipids, red in illustrations in the paper, melted at higher temperatures than short lipids, represented by green. The researchers melted the lipids together, then placed them on a surface to c...

How nature tinkers with the cellular clock

... that each machine is active only during the right phase of the cycle. Comparing cell cycle genes that are conserved between humans, yeasts and thale cress, Peer Bork and colleagues at EMBL and DTU found that while many genes in each organism are expressed only at specific times of the cell cycle, it is n...

Melatonin improves mood in winter depression

...the later dawn in winter, resulting in a circadian phase delay with respect to sleep similar to what happen...AD patients is bright light exposure, which causes phase advances when scheduled in the morning. Because patients know when they are exposed to bright light,...

Three-in-one virus killer prevents common, often fatal infections

...The journal has posted the findings online. The phase 1 trial, funded by the National Heart, Lung, and Blood Institute, one of the National Institutes of Health, tested the first multivirus killer of its kind, called Trivirus-specific cytotoxic T lymphocytes (CTLs), which control infections caused by th...

Sandia research to focus on early detection of harmful algal blooms

...paration. The long-term goal, should the initial phase of the Sandia research go as planned, is to develop small, lightweight devices that could be fielded by oceanographers and marine biologists as part of their regular monitoring systems. In addition to Sandia's Lane and VanderNoot, collaborators inc...

Gene therapy study takes aim at prostate cancer

... preventing recurrence of the disease. The first phase of the study is designed to test the safety of the treatment and determine the proper dosage of gene, said Dr. Dov Kadmon, professor of urology at BCM. It will be carried out in the department of urology at BCM as well as at Ben Taub General Hospital...

Ocean temperature predicts spread of marine species

...cies, O'Connor said. "For many animals, the larval phase is the only chance for babies to get away from parents. Dispersal prevents inbreeding; for some species, this is a time to move from breeding ground to habitat where they'll mature," she said. But less than 1 percent of larvae survive dispersal. T...

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