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Tag: "phase" at biology news

Gene that makes people 'early to bed and early to rise' demystified

...ise," a condition known as familial advanced sleep phase syndrome (FASPS), offered one of the first glimpses into the genetic basis of sleep in humans. Now, researchers report in the Jan. 12, 2007 issue of the journal Cell, published by Cell Press, new evidence that helps to explain just how their bodies' ...

Cancer vaccines -- Taking a jab at cancer by stimulating the immune system

...vaccine: Abstract 4900 Ongoing evaluation of a phase II trial of a human papillomavirus vaccine, develo...eting p53 in head and neck squamous cell cancer. A phase I clinical trial of the vaccine is currently underway at the University of Pittsburgh Cancer Institu...

UCSF brain tumor vaccine trial shows promising results

...provement in overall survival rates, although this phase 1/2 study is not designed to primarily evaluate ef...al. Based on these results, a larger, multi-center phase 2 study is planned for late 2007. Derived from each individual’s tumor, vitespen contains the “fi...

Darwin's famous finches and Venter's marine microbes

...les collected from surface waters during the first phase (or first third) of the voyage, which led the Sorcerer II from Newfoundland through the Panama Canal and Galapagos Island on to French Polynesia. Venter’s crew siphoned seawater through a series of increasingly fine filters to collect the microbes, w...

Keeping the body in sync -- The stability of cellular clocks

...ion studies in families affected by advanced sleep phase syndrome. Circadian rhythms are cyclical changes in physiology, gene expression, and behavior that run on a cycle of approximately one day, even in conditions of constant light or darkness. Peripheral organs in the body have their own cellular clo...

Autism gene identified by researchers at Yale working with a global research consortium

...ver the genes that cause the disorder. This second phase represents a $14.5 million, three-year investment by Autism Speaks, the British Medical Research Council, the Health Research Board of Ireland, Genome Canada and its partners, Canadian Institutes for Health Research, Southwest Autism Research and Re...

Early-stage sperm cells created from human bone marrow

...lled spermatagonial stem cells, which are an early phase of the male germ cell development. In most men, spermatagonial cells eventually develop into mature, functional sperm but this progression was not achieved in this experiment. Earlier research led by Prof Nayernia using mice, published in La...

Study shows hope for early diagnosis of Alzheimer's

... of the brain that seem to be attacked at an early phase of Alzheimer’s disease, but the results are not always conclusive. Polikar and his students analyzed the data using sophisticated signal processing, pattern recognition and artificial intelligence techniques to explore the hypothesis that the enti...

Chemo combination improves survival in asbestos-related cancer

... "There is no way of diagnosing the premalignant phase during the latent period of 15 to 20 years," Green added. "Many of these patients smoke and are in economically disadvantaged communities. Many individuals have moved away from heavy industries and may not admit or know they were exposed to asbestos ...

Cold sore virus might play role in Alzheimer's disease

...r a lifetime, periodically flaring up in a "lytic" phase where it causes cell damage, then retreating and seeking safe harbor within the body's nerves in a "latent" phase. The virus spends most of its time in the latent phase, sequestered in cells, not active and not replicating. But occasionally, when tri...

Africa's first large-scale HIV vaccine study launches

...erent strains of HIV-1." The study is known as a phase IIb or "test of concept" efficacy trial because it... and already has been studied for several years in phase I and II trials involving thousands of volunteers in the Americas, Africa and Australia to evaluate ...

Study calculates patient time costs associated with cancer care

...e. "For 2005, the estimated cost for the initial phase of care alone was approximately $2.3 billion," the authors write. These estimates could be combined with estimates of direct and indirect costs to better understand the overall burden of cancer in the United States, the authors write. "What we see ...

Fascinating spider silk

...mentally, the spinning of spider silk represents a phase change from a solution into a solid thread; but th...aration of two different fluid phases. Whereas one phase consisted of protein dimers, the second consisted of oligomers—multiple protein units linked togethe...

Brain's reward circuit activity ebbs and flows with a woman's hormonal cycle

...cuitry was more active if they were in a menstrual phase preceding ovulation and dominated by estrogen, compared to a phase when estrogen and progesterone are present. "These first pictures of sex hormones influencing rewa...

Stanford-led study closes in on genes that may predispose some people to severe depression

...elp the search for better treatments." The next phase of the consortium's research is already under way. This phase is an even more detailed look at more than 2,000 individuals to identify specific genes where ther...

Cure for cancer one step closer

... with researchers around the world, and two vapour phase nitrogen storage vessels (-196ºC) and two -80ºC freezers which have the capacity to house in excess of 164,000 tissue and blood samples. The small sections of tissue collected from patients will be stored in cryogenic vials which will help preserv...

In Iran, cheetahs collared for the first time

...cientific team in Iran and represents a unique new phase of WCS's long-term involvement in the country. The new collars will furnish very precise information on the routes that cheetahs use to travel between protected areas, and will reveal the key features in the landscapes that are critical to their surv...

Herpes infection may be symbiotic, help beat back some bacteria

...ll the mice. When herpes was still in the acute phase of infection, no protective effect was present. When scientists exposed the mice to a mutant herpes virus that can infect but cannot establish latency, the herpes infection did not confer resistance. The protective effect could be produced by two dif...

Protein enables discovery of quantum effect in photosynthesis

...lain its extreme efficiency, in that vast areas of phase space can be sampled effectively to find the most efficient path for energy transfer. "We have a very detailed molecular structure of this protein and we understand the electronic properties of it very well, too," said Blankenship. "It's taught ...

Eavesdropping comes naturally to young song sparrows

...ght to learn their songs in two phases. The first phase occurs in their first summer, when they hear and m...m hearing one another or the tutors. The second phase of the study began when the birds were about 8 months old. This time only two of the adult tutors w...

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