A New Era of Hope for the World's Most Neglected Diseases
...epresented the lowest-priority markets for Western pharmaceutical manufacturers. Bernard Pécoul of the Drugs for Neglected Diseases Initiative (DNDi) has called these patients “the forgotten people.?/p> The conventional wisdom is that the outlook for such patients is hopeless. As one of us has argued, “[They] h...Mining biotech's data mother lode
...is was the biggest problem they face." Currently, pharmaceutical and biotech companies produce vast quantities of raw data on the problems that interests them. Microarrays process thousands of samples to discover what genes are over expressing. These over-expressing genes ?numbering sometimes in their thousands, t...Scientists pinpoint inflammation gene
...covery will be of great interest to biomedical and pharmaceutical researchers because of an already heightened understanding of the role of inflammation in so many human disorders. "Practically every common disease involves an inflammation component," said John Blangero, Ph.D., a scientist at the Southwest Foundat...Scientists move forward understanding of schizophrenia
...rgh and Glasgow, together with scientists from the pharmaceutical company Merck, Sharp & Dohme Limited, report t...by the two Universities and by scientists from the pharmaceutical company Merck Sharpe and Dohme reveals that damage to the gene PDE4B is also seen to increase the ri...Seaweed yields new compounds with pharmaceutical potential
...s have discovered 10 new molecular structures with pharmaceutical potential in a species of red seaweed that lives i...y them in a more complex model system." The U.S. pharmaceutical company Bristol Myers Squibb is collaborating with Georgia Tech researchers to determine how some of...UK is first to administer new anti-clotting technology
... such as Dr. Steinhubl. Leaders of technology and pharmaceutical companies have visited us in Lexington and are entrusting us to pioneer the next-generation of medicines and devices to improve healthcare," said Dr. David Moliterno, professor and vice chair of medicine, and chief, division of cardiovascular medicin...UT Southwestern researchers develop screening test for cells that activate immune system
...r. Takashima. The DC biosensor system should help pharmaceutical and biotech companies sift through large numbers of chemicals for ones that tell the dendritic cells to launch the immune response. It may also prove useful in identifying biothreat agents because it detects infectious pathogens with high sensitivit...Researcher says flu responders can learn from 1918 epidemic
...l city." Medical knowledge, research findings and pharmaceutical developments provide some hope that 21st century Americans might not suffer the fate of their forebears, but Higgins said that survival might depend on the simple concept of community planning. In studying the metropolitan areas around the state of ......port from harvesting in the field to marketing the pharmaceutical product. This includes assisting with the science ...re extensive, not only to Welsh bioscience and the pharmaceutical industry, but also to the ageing population." ...Study findings offer potential new targets for antibiotics
...ntibiotics. These sites are what may one day give pharmaceutical companies an edge in creating new antibiotics in order to keep ahead of bacteria's clever way of developing resistance to antibiotics. "Now that we know these other sites exist and that they could be potential targets for antibiotics, the next step ...Vaginal gel may provide a new approach to HIV prevention
...ind joint announcement, two of the world's leading pharmaceutical companies, Merck & Co. and Bristol-Myers Squib...th Summit, this agreement marks the first time any pharmaceutical company has licensed an anti-HIV compound for development as a microbicide when the class of drugs i...UW-Madison scientists zero in on drugs' sweet spots
...ed by University of Wisconsin-Madison professor of pharmaceutical sciences Jon S. Thorson, describes a series of exp...d help make natural products more appealing to the pharmaceutical industry. Despite the fact that 60-75 percent of drugs approved to treat infectious disease and canc...New NIAID grants strengthen national biodefense and emerging infectious diseases research network
...om academia, government, biotech companies and the pharmaceutical industry * provide facilities and scientific support to first responders in the event of a national biodefense emergency The previously established RCEs in the network are led by Duke University, Harvard Medical School, New York State Department......se are anti-fungals or treatments for cancer. Many pharmaceutical drugs on the market, from aspirin to cholesterol-l...sea creatures. It is part of a developing focus on pharmaceutical chemistry within the UC Davis chemistry department, including research on biologically active molecu...New plant DNA libraries provides massive boost to world's plant researchers
...orking in agriculture and horticulture and also to pharmaceutical research teams interested in the medicinal properties of plants. The new libraries have two key features that will make them particularly attractive to researchers. Firstly, there are genomic libraries from 20 different plant species, a far wider ra...Promising therapies for haemophilia & heart disease
...rt clinicians to potentially fatal events. Several pharmaceutical companies are now searching for compounds that target P-selectin. "This would represent a major breakthrough in diagnosing and treating cardiovascular disease," she said. "There is still a great deal to be learned about this protein. This research c...Cells direct membrane traffic by channel width
...anding the principles could provide new, effective pharmaceutical targets to control the channels to help treat disease. Study co-authors were group director Klaus Schulten and Yi Wang, a doctoral student in molecular and cell biology. ...New law for resolution allows unprecedented sharpness in fluorescence microscopy
...s method may substantially improve the analysis of pharmaceutical active ingredients and protein interactions in cells in future. Original work: [1]Hell, S. W. Strategy for far-field optical imaging and writing without diffraction limit. Phys. Lett. A 326(1-2): 140-145 (2004) [2] Westphal, V., and S. W. Hell Nan...Researchers find how some antibiotics kill bacteria
...a parasites depend on. "It's the kind of drug the pharmaceutical business wants to produce," Artsimovitch said. "They're looking for the broadest range of antibiotics possible. Rifamycins would be ideal drugs if we could figure out how to get rid of resistance." ......llion-dollar market, with growing visibility among pharmaceutical companies. The currently marketed drug is an injec...search for Biota. "Others, including several large pharmaceutical companies, have discovered and disclosed RSV antivirals, but many are inhaled products. Orally effec...