pharmaceutical 2 4

Tag: "pharmaceutical" at biology news

Therapeutic prospects beyond Vioxx

... and inflammation. This has prompted several large pharmaceutical companies to develop drugs targeting this enzyme. Such inhibitors will soon enter human trials. FitzGerald and his colleagues showed that deletion of mPGES-1, in contrast to deletion or inhibition of COX-2, did not predispose the animals to thrombos...

Research could lead to better drugs and whiter whites

...f how enzymes work is important to a wide range of pharmaceutical and industrial fields," said Professor Nigel Scrutton, one of the lead researchers at Manchester. "Enzymes are central to the existence of life because most chemical reactions in our cells would take place too slowly or produce a different outcome w...

Two NIH initiatives launch intensive efforts to find roots of common diseases

...the National Institutes of Health (FNIH) and major pharmaceutical and biotechnology companies, especially Pfizer Glo...nd data access committees. "Our partnership with pharmaceutical and biotech companies to speed up this research exemplifies the aim Congress had in mind when it est...

Georgia Tech accelerates drug discovery with new IBM supercomputing cluster

...lore new commercial opportunities in the fields of pharmaceutical science and healthcare. ...

Rutgers researchers find fat gene

...ating enzyme. "Lipin activity may be an important pharmaceutical target for the control of body fat in humans, treating conditions that range from obesity to the loss of fat beneath the skin, as seen in HIV patients, " said George M. Carman, a professor in Rutgers' department of food science. In a paper published...

Researchers use dirt to stay one step ahead of antibiotic resistance

...rugs for resistance in soil bacteria, not only can pharmaceutical companies can gain a better understanding of what may emerge in the future as clinical problems, but sufficient warning can be given to hospital microbiology laboratories, physicians and the drug discovery sector to allow for the development of diagn...

World faces challenge as life expectancies lengthen, scientist says

...ibute medicines to those who need them most. "Big pharmaceutical companies have a well-established track record of being very difficult when it comes to making things available to those who can't pay for them," he said. If anti-aging technologies are distributed in the unchecked free market, "it's entirely likely...

Chemical warfare agent detection technology used to treat lung disease

...s to explore the use of IMS measurement within the pharmaceutical and biomedical fields. Alongside Professor Colin Creaser from Nottingham Trent University he will lead a consortium of experts and industrial partners, who will be evaluating DMS and IMS potential in areas such as high-speed separations of complex mi...

Researchers get neurons and silicon talking

...d and sophisticated drug screening systems for the pharmaceutical industry. "Pharmaceutical companies could use the chip to test the effect of drugs on neurons, to quickly discover promising avenues of research," says Professor Stefano Vassanelli, a molecular biologist with the University of Padua in Italy, and on...

Mining for gems in the fungal genome

... can use to find secondary metabolites that are of pharmaceutical interest," says Keller. Although the team worked on a widely studied fungus, Aspergillus nidulans, the method can be used to find secondary metabolites in many other fungal species. While primary metabolites are essential compounds that aid basic...

New Rotavirus vaccine joins routine infant immunization schedule

...f the largest clinical trials to be performed by a pharmaceutical company. The company's data showed that the vaccine prevented 98 percent of severe cases of rotavirus gastroenteritis and 74 percent of routine cases, compared to a placebo. Furthermore, the vaccine showed no increased risk of intussusception, a tele...

Intelligently designed molecular evolution

...led this study. "This technology could be used by pharmaceutical manufacturers in the future to create specific enz...Yasuo Yoshikuni, and Thomas Ferrin, a professor of pharmaceutical chemistry and biopharmaceutical sciences at UC San Francisco. The results of this study were repor...

Cellular scale drug delivery from the inside out

...o control whether or not the particle delivers its pharmaceutical payload. "First, the nanospheres are only about 200 nanometers in diameter, roughly the size of a virus, so they won't trigger an immune response in the body," Lin said. "They're also biocompatible so they can be readily absorbed by the cells." B...

Dog genome sequenced

...og model system particularly useful in medical and pharmaceutical research. The Dog and Its Genome puts these and other aspects of the dog into context and focus. In the book's 26 chapters, dog experts cover morphological and behavioral variation in dogs, their origins and domestication, and characteristics of ...

Scientists fetch useful information from dog genome publications

...og model system particularly useful in medical and pharmaceutical research. The Dog and Its Genome puts these and other aspects of the dog into context and focus. In the book's 26 chapters, dog experts cover morphological and behavioral variation in dogs, their origins and domestication, and characteristics of ...

Mouse study: New muscle-building agent beats all previous ones

...o first created "mighty mice" have developed, with pharmaceutical company Wyeth and the biotechnology firm MetaMorphix, an agent that's more effective at increasing muscle mass in mice than a related potential treatment for muscular dystrophy now in clinical trials. The new agent is a version of a cellular docking...

Technique offers new view of dynamic biological landscape

...e. Understanding such interactions could also give pharmaceutical researchers clues to the magnitude of possible side effects of drugs under development. The development of combination drug therapies, such as for cancer or viruses, could also benefit from the E-MAP approach. "In such cases, clinicians want to kno...

Genes involved in biofilms

... to identify action targets for the development of pharmaceutical drugs to combat these infections. The PhD, entitled Identification and characterisation of new factors involved in the processes of formation of biofilm from Gram-positive bacteria. Chronic infections Biofilms are communities of microorganism...

Limiting the damage in stroke

...NF-kB passes a variety of other important signals, pharmaceutical companies have already been developing molecules that target parts of the signaling pathway. ...

Sangamo BioSciences demonstrates its ZFP treatment protects cells from HIV infection

...n to be resistant to HIV infection. Several major pharmaceutical companies have initiated programs to develop small molecule drugs to block HIV binding to CCR5, but in recent months two trials have been halted, one due to reports of liver toxicity of the candidate drug. We believe that using ZFNs to permanently m...

1 2 3 4 5 6 7 8