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Tag: "pharmaceutical" at biology news

'Smart' genetic therapy helps the body to heal itself

...ortunately, there is very little interest from the pharmaceutical industry in clinical trials for rare disorders. However, the long-term outcome could be both improved therapy to enable a better quality of life for SMA patients, and also the introduction of neonatal screening so that therapy could be started befo...

Loosen up, DNA: Leukemia gene changes genetic packaging

...other, not both." The work fits in squarely with pharmaceutical research on experimental drugs known as HDAC (histone deacetylase) inhibitors, which affect chromatin structure and play a role in turning on or off whole swaths of DNA. Such drugs are under investigation for leukemia and several other diseases. Base...

3-D model reveals secrets of metastasis

...;TM s Biological Engineering Division. He believes pharmaceutical companies will eventually use three-dimensional assays, accompanied by appropriate computational models such as that also recently published by Zaman (in Biophysical Journal in 2005), to determine how drugs affect metastasis. But technology must im...

Ten years later, Dolly is still making headlines

...ill discuss a variety of critical issues affecting pharmaceutical biotechnology including Biogenerics, a field that ...xciting and challenging time to be in the field of pharmaceutical sciences than now." The following topics will headline this year's meeting: Creator of "Dolly" ...

Cells use mix-and-match approach to tailor regulation of genes

...turn the expression of those genes on or off. Some pharmaceutical companies are also hoping to develop drugs that selectively block the binding of transcription factors as a way to short-circuit the harmful effects of diseases, and researchers at the University of California, San Diego on June 16 reported new findi...

Magnetism and mimicry of nature hold hope for better medicine, environmental safety

...al analysis. Such technologies can also give the pharmaceutical industry improved ways to screen for new drugs by being able to run several types of tests simultaneously on an extremely small scale. The next step in developing this technology is under way in Hayes' laboratory and through the team's collaboratio...

Deep-water discovery

...ganisms living within them, produce chemicals with pharmaceutical potential. A key goal is to find and collect organisms that have never been seen. The team will collect other organisms as well because even well-known species can produce different and potentially important chemicals depending on the depth, temper...

Drug discovery team to explore newly discovered deep-sea reefs

...ganisms living within them, produce chemicals with pharmaceutical potential. A key goal is to find and collect organisms that have never been seen, which happens on almost every one of the Harbor Branch team's expeditions. Other organisms will also be collected because even well known species can produce different ...

Selenium-protein deficiency raises prostate cancer risk

...istics; and Daniel Lantvit, research specialist in pharmaceutical sciences. ...

Tamoxifen for breast cancer prevention does not benefit most women

...e cost-effectiveness equation could be improved if pharmaceutical prices were negotiated at a national level. At Canadian prices, for example, the researchers showed that taking tamoxifen to prevent breast cancer comes to $123,780 per year of life saved for women at the 1.67-percent risk level. In comparison, ann...

Pest control research leads to pain control discovery

...ies or side effects of the medications. Merck, the pharmaceutical company that manufactured and marketed Vioxx, a Cox-2 selective nonsteroidal anti-inflammatory drug (NSAID), voluntarily pulled the pain killer from the market in September 2004 due to safety concerns. A 12-month study, published in 2000, showed a fo...

Drug triggers body's mechanism to reverse aging effect on memory process

...rding to the researchers, this study suggests that pharmaceutical products based on ampakines can be developed that do not need to be in the system at all times in order to be effective. Most drugs used to deal with central nervous system disorders, such as Parkinson's disease, are only effective when they are in t...

Scientists uncover rules for gene amplification

... forming large genomic regions. Some strategies of pharmaceutical research in cancer prevention and treatment could involve curbing cancer development via restricting gene amplification. The first step towards achieving this is to discover the rules that govern whether an amplification event is a double minute or a...

Biomarkers may hone anti-aging therapies

...ve Dermatology. "There's a lot of interest in the pharmaceutical and cosmetic industries in developing products that will minimize or reduce certain signs of aging," said James Sligh Jr., M.D., Ph.D., assistant professor of Medicine and Cell & Developmental Biology. "The quantifiable biomarkers we've character...

Mutation in blood stem cells provides clues to cancer development

...orking with specific inhibitors developed by local pharmaceutical companies, the UCSD and Stanford researchers plan to conduct clinical trials in the near future and are working with colleagues at Harvard University, the Mayo Clinic, and the M.D. Anderson Cancer Center in Houston to help expedite these trials. The...

Psychotropic drug prescriptions for teens surge 250 percent over 7 year period

...drugs. Nevertheless, the study noted that overall, pharmaceutical companies increased their spending on television advertising six fold, to $1.5 billion, between 1996 and 2000, with the trend accelerating after 1997, when the Food and Drug Administration Modernization Act was passed. However, at the same time teen...

Taipan venom no snake oil

...or X is being evaluated for clinical trials by bio pharmaceutical development company QRxPharma. "Australian snakes literally have a two-pronged attack when they bite their prey," Dr St Pierre said. "Firstly, venom injection causes massive blood clots instantaneously followed by paralysis as a result of neurotoxi...

Retinol for combating leukemia cells

...These and others should be taken into account if a pharmaceutical to combat leukemias based on retinamide is to be m...e same treatment. This is why lines of medical and pharmaceutical research increasingly mention the need to know the genetic characteristics of each patient in order ...

Major WHO study concludes calcium supplements can reduce complications during pregnancy

...these simulations will motivate the researchers in pharmaceutical or biotechnology companies to pursue the design of a new kind of inhibitor," Perryman said. "We are trying to lead other scientists toward a completely novel approach to fighting HIV infections." In contrast to the colorful but static images on the ...

Computer simulation hints at new HIV drug target

...these simulations will motivate the researchers in pharmaceutical or biotechnology companies to pursue the design of a new kind of inhibitor," Perryman said. "We are trying to lead other scientists toward a completely novel approach to fighting HIV infections." In contrast to the colorful but static images on the ...

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