Gene-specific Ebola therapies protect non-human primates from lethal disease
...rrupt normal Ebola virus replication. The work was performed in collaboration with AVI BioPharma, a U.S. biotec...date morpholino oligomers, or PMOs, the team first performed a series of studies to identify PMOs that demonstrated activity against Ebola virus. Next, three of ...Two NIH initiatives launch intensive efforts to find roots of common diseases
...ng their DNA. The genotyping work itself will be performed by either commercial or government laboratories. The initial GAIN genotyping supported by Pfizer will be carried out by Perlegen Sciences, Inc., of Mountain View, Calif., and will start in late summer 2006; Pfizer is contributing these Perlegen-produ...New analysis shows three human migrations out of Africa
...pleton analyzed ten different haplotype trees and performed phylogeographic analyses that reconstructed the history of the species through space and time. Three years later, he had 25 regions to analyze and the data provided molecular evidence of a third migration, this one the oldest, back to 1.9 million ...Morning grogginess more debilitating than sleep deprivation, according to CU-Boulder study
...inertia. "These were very healthy people who had performed the test hundreds of times, making the results even more profound," said Wright. ...Oops! Researchers publish new findings on the brain's response to costly mistakes
...orders Program in the Department of Psychiatry, he performed a study in OCD patients that showed heightened response to errors in the same area. Now, the fMRI technique has allowed the researchers to localize this response even more precisely. The fMRI scanner uses magnetic fields to create images based on bl...Plant-derived vaccines safeguard against deadly plague
... Testing using an aerosolized form of plague was performed by Chad Roy and Robert Webb at the U.S. Army Medical Research Institute of Infectious Disease at Fort Detrick, Maryland. This project was also the first comparison study designed to test more than one kind of antigen during the same challenge. "Th...Zebra finches remember songs dad sang
...dies the neurobiology of song production. The team performed the experiments reported in the paper in Vicario's...n can tell us how this imitation trick is actually performed by cells in the brain," Vicario says. "The bird's brain provides a laboratory for studying how memor...New test to detect rare proteins in blood
... is remarkably adaptable to any protein and can be performed in an automated format," notes Greene. He states that the technology will soon be robotized so as to be able to screen for many rare disease-causing proteins using tiny amounts of blood. "It is even possible that one could screen for multiple disease...Robot assisted surgery more accurate than conventional surgery
...osition, but only 40 percent of the conventionally performed cases achieved this level of accuracy. The team found there were no additional side effects from using robot assisted surgery, and recovery from surgery was quicker in most cases. Professor Justin Cobb, from Imperial College London, who led the r...Sex: It's costly but worth it. Just ask a microbe
...uce on their own, the first two groups of microbes performed efficiently and prolifically. The microbe couples, however, were slower to reproduce. But Xu also found that a fair bit of fluffing and flirting goes on when mixed pairs slide into a petri dish, and the results can be detrimental to their fitness. "...Avian flu transmission to humans may be higher than thought
... a combination of cough and fever). The study was performed from April 1 to June 30, 2004. As background information, the authors explain that in Vietnam, an epidemic of HPAI in poultry, subtype H5N1, has been ongoing since 2003, despite efforts by the government to eliminate the diseased birds from flo...Scientists discover dozens of new species in 'Lost World' of western New Guinea
...sts watched as a male Berlepsch's bird of paradise performed a mating dance for an attending female in the field camp. This was the first time a live male of the species had been observed by Western scientists, and proved that the Foja Mountains was the species' true home. The expedition took place almost 25 ......ers from healthy controls. The research, which was performed in California, was recently documented by the BBC in the United Kingdom, and is soon to be aired in the United States. Other scientific studies have documented the abilities of dogs to identify chemicals that are diluted as low as parts per trillio...Salk researchers make fast strides towards understanding how our body controls walking
...contribute to the CPG, Goulding and his colleagues performed electrophysical studies on isolated spinal cords. They found that, while normal spinal cords showed a standard pattern of activity that mimics walking, the rhythmic pattern in spinals cords lacking functional V1 neurons had slowed to a crawl. "From ...Poison dart frog mimics gain when birds learn to stay away
...icry is to gain protection from predation." Darst performed predator experiments using domestic chicks she collected from villages outside of Quito, Ecuador. The chicks quickly learned to avoid the highly toxic frogs during training sessions and subsequently avoided all other similar frogs, even those that we...Resveratrol prolongs lifespan and delays onset of aging-related traits in a short-lived vertebrate
..., until now, life-long pharmacological trials were performed in the worm or fly model organisms because of their very small size, very short natural lifespan, and affordable cultivation costs. Laboratory mice, on the other hand, live more than two years and are relatively expensive to maintain, making large-sc...Genome changes tracked during multiple myeloma initiation, progression and treatment
...Arkansas for Medical Sciences and their colleagues performed a high-resolution and integrated analysis of gene copy number alterations and expression profiles of outcome-annotated MM clinical specimens. The researchers discovered a high level of molecular heterogeneity typified by many new recurrent amplific...Genetically engineered mosquitoes show resistance to dengue fever virus
...te and State University. James and his colleagues performed tests on a family of mosquitoes descended from one of the original embryos that survived the procedure. They found that the vast majority of that family was highly resistant to dengue infection. They also were able to detect the engineered RNA in the...Groovy protein essential for promoting cancer development
...the best candidates for further analysis. Jacobs performed these experiments on fragments of the telomerase enzyme from a variety of organisms, and found that only a fragment from Tetrahymena -- the single-celled organism in which telomerase was first discovered -- would work. The researchers named the pr......the best candidates for further analysis. Jacobs performed these experiments on fragments of the telomerase enzyme from a variety of organisms, and found that only a fragment from Tetrahymena -- the single-celled organism in which telomerase was first discovered -- would work. The researchers named the pr...