Malfunctioning bone marrow cells sabotage nerve cells in diabetes
...ience in Shiga, Japan, in collaboration with Chan, performed numerous experiments in diabetic rats and mice. Their work defined the role of the aberrant cells in causing neuropathy. They found that, in diabetes, only nerve cells that have fused with bone marrow cells display the abnormal function and prematu...New Lab Research May Help Those Deafened By Immune System Attack
...standard criteria and the results of hearing tests performed before and after treatment. They also considered patients' other autoimmune diseases, the length and pace of hearing loss progression before treatment, and age and gender. Thirty of the patients were female, and 33 male; their average age was 47, re...MicroRNA tweaks protein that controls early heart development
...gy at UT Southwestern, where he and his colleagues performed the Nature research. He currently is director of the Gladstone Institute of Cardiovascular Disease and professor of pediatrics at the University of California, San Francisco. Dr. Srivastava said that if the microRNA is not functioning properly, hear...Neurologix announces positive results of gene therapy clinical trial in Parkinson's disease
...owing treatment. The gene therapy procedures were performed at NewYork-Presbyterian Hospital/Weill Cornell Med...ry entailed a stereotactic neurosurgical procedure performed under local anesthesia with the patient awake. First, MRI was used to image the target subthalamic ...New imaging technology shown to detect pancreatic inflammation in type 1 diabetes
...is a biopsy of the pancreas, which is almost never performed because it is an invasive and potentially risky procedure. "The most exciting aspect of this study is that it demonstrates that we can, at least in mice, use a non-invasive imaging method to predict at a very early time whether a drug will stop the...Why do aneurysms form? New studies suggest leading role for white blood cells
...ion of the aneurysm." Upchurch and his colleagues performed one of the studies using mice that had been treate...the neutrophil-deficient mice. But the researchers performed more experiments that showed that the lack of MMP-8 was not enough by itself to keep aneurysms from ......estigate responses in Drosophila melanogaster, she performed experiments dropping black discs from different angles, on a collision course with the flies. Capturing the responses on video, she showed that flies escaped by means of jumping in a forward fashion and directly away from the object, in addition to u...Nanoscale method for investigating living systems
...th other cells. This is how signal transduction is performed in your body, but it is also how chemicals react with your body. When, for example, caffeine enters a cell it stimulates the opening and closing of these ion channels. What we've found is that these quantum dots can form artificial pores that enhance...Two designer drugs hit same lung cancer target, but only one is effective
...in action is the apparent explanation for why they performed differently against the mutant EGFR cells. The scientists also looked at cases of four NSCLC patients with EGFR mutations who had been treated with the two drugs. The scientists' predictions were confirmed: all patients had some tumor shrinkage when...Results of world's first gene therapy trial for arthritis show approach safe, feasible
... the results also provide assurance that it can be performed without causing undue harm to patients. The clinical trial, which was conducted at the University of Pittsburgh School of Medicine between 1996 and 1999, involved nine women who had genetically modified cells injected into their arthritic knuckles a...UCLA researchers identify key enzyme linked to childhood blindness
...n, visiting assistant researcher in ophthalmology, performed an expression screen in cultured human cells, looking for a gene that caused these cells to convert vitamin A into 11 cis retinol. The researchers are now studying the effects on retinoid isomerase activity of specific disease causing mutations in t...'Cookbook recipes' would cure disease with nontoxic DNA delivery systems
...National Academy of Sciences, researchers have now performed a careful, comprehensive study to see how negatively charged lipids stick to negatively charged DNA and self-organize into structures. "Many research groups have made concoctions with ingredients in different proportions and then assessed their effe...Surgical Robot 'Scrubs In' At UNC, May Be More Precise Than Conventional Surgery
...tal and associate professor of surgery at UNC, has performed several successful pediatric operations with the d... decade, RALRP will become the most common surgery performed for patients with prostate cancer. The robot improves the view that the surgeon has, and its instrum...Screen all at risk for HIV, plus pregnant women
...tal and associate professor of surgery at UNC, has performed several successful pediatric operations with the d... decade, RALRP will become the most common surgery performed for patients with prostate cancer. The robot improves the view that the surgeon has, and its instrum...FDA: 'Highly Unlikely' Green Tea Lowers Cancer Risk
...tal and associate professor of surgery at UNC, has performed several successful pediatric operations with the d... decade, RALRP will become the most common surgery performed for patients with prostate cancer. The robot improves the view that the surgeon has, and its instrum...Tropical Deforestation affects rainfall in the U.S. and around the globe
...t their results are based on numerical simulations performed with a single general circulation model and that reproducing the experiment with other computer models using different atmospheric variables would be beneficial. Current research is attempting to answer why deforestation has such a major influence on...Less virulent strains of avian influenza can infect humans
...icularly ill or dying chickens. The investigators performed a serologic analysis of individuals exposed to infection during the outbreaks, collecting 983 blood samples from poultry farm workers in the outbreak regions. Blood was tested using three different techniques to ensure the validity of results. The o...Transplanting Animal Organs Could Soon Be A Reality
...icularly ill or dying chickens. The investigators performed a serologic analysis of individuals exposed to infection during the outbreaks, collecting 983 blood samples from poultry farm workers in the outbreak regions. Blood was tested using three different techniques to ensure the validity of results. The o...Brain networks change according to cognitive task
... researchers discovered that the brain region that performed the integration of information shifted depending on the task their subjects performed. In this study, the subjects were assigned two language tasks. In both, subjects were asked to read individual words and then make a spelling or rhyming judgment. ...First Whole Genome Map of Genetic Variability in Parkinson’s Disease
...icularly ill or dying chickens. The investigators performed a serologic analysis of individuals exposed to infection during the outbreaks, collecting 983 blood samples from poultry farm workers in the outbreak regions. Blood was tested using three different techniques to ensure the validity of results. The o...