Roche clinical trial registry and results database launched
... Roche works to ensure that all its activities are performed in accordance with ethical and regulatory requirements. Moreover, Roche is strongly committed to verifying adherence to compliance policies. Adequate and ongoing peer review is a key prerequisite for maintaining high ethical standards in Roche’s clin...New tumor-suppressor gene discovered
...e tumor-causing candidates down to two genes, then performed molecular-biology experiments with them both, reve... which turned out to be the case. The researchers performed three experiments to test whether the mats and wts genes interact genetically. In the first experime...Grasping metaphors: UC San Diego research ties brain area to figures of speech
...another ?patients with damage to the angular gyrus performed at the level of chance. Three age-matched control...er hand, with lesions in other areas of the brain, performed normally both with proverbs and the booba/kiki test. Disproportionately larger in hominids than oth...Study reveals dramatic difference between breast cancers in US and Africa
...ter from Senegal. The gene expression analysis was performed in Olopade's laboratory at the University of Chicago. "We now have the world's largest collection of tumor samples from Africa," said Olopade. "Francis did most of that over the course of one year. That should give you some idea of how neglected thi...Migratory songbirds have a specialized night-vision brain area
...ally specialized for night-vision, the researchers performed the same gene expression analysis on the night-migratory songbird species with the birds' eyes covered. The researchers found that blocking night-time vision dramatically reduced gene activity in cluster N. "This result confirmed that night-migrator...Researchers develop assay that could be applied to drug screening
...ost important 'nano-machines' in action. The work, performed in collaboration with English and French scientists, provides new insight into the machinery cells use to internalize cell surface receptors. All cells traffic protein cargos across their outer membrane, and one of the most important routes for carg...Scientists generate patient-specific stem cells, Science study says
...of stem cell research. The Korean researchers who performed this stem cell research improved upon their protocols that yielded the first embryonic stem cell line from a cloned human blastocyst. (Science 12 March 2004; 303: 1669-1674; published online 12 February 2004.) In their new paper, Science author Woo ...SuperLigands - a database of ligand structures derived from the Protein Data Bank
...of stem cell research. The Korean researchers who performed this stem cell research improved upon their protocols that yielded the first embryonic stem cell line from a cloned human blastocyst. (Science 12 March 2004; 303: 1669-1674; published online 12 February 2004.) In their new paper, Science author Woo ......particular phenotype. Shaulsky and his co-authors performed their work in Dictyostelium (Dictyostelium discoideum), a form of soil amoeba used in the laboratory because many of its 10,000 genes are homologues or equivalents of genes found in humans. Using microarray data alone, they determined the orders in ...Whole-body MRI Takes Less Than 20 Min To Scan A Patient's Entire Body For Cancer Spread To Bone
...chers from the Clinica Girona in Catalonia, Spain, performed whole-body MRI on 42 patients with known malignant...0% better than bone scintigraphy, which is usually performed for this purpose. “Whole-body MRI is a relatively new technique that uses an automatic moving table...UCLA study assesses cost-effectiveness of Hepatitis B drugs
...reater Los Angeles Healthcare System. Researchers performed an economic analysis comparing the cost-effectiveness of five competing drug treatment strategies for chronic hepatitis B: 1) No treatment at all 2) Interferon alone 3) Lamivudine alone 4) Adefovir alone 5) Beginning therapy with lamivudine, but chan...Penn Researchers Use Robotic Surgery
...tic technology. In the second study, the surgeons performed a variety of surgical procedures on a human cadaver. They concluded that robotic surgery may shorten operating time and allow for minimally invasive treatment of more cancer patients. The self-contained daVinci robotic system has three main componen...Two new retroviruses—transmitted from animals—identified
...tic technology. In the second study, the surgeons performed a variety of surgical procedures on a human cadaver. They concluded that robotic surgery may shorten operating time and allow for minimally invasive treatment of more cancer patients. The self-contained daVinci robotic system has three main componen...Researchers Find New Technique To Identify Fetal Genetic Material From Amniotic Fluid
...l sonography. In addition, genetic analysis can be performed on amniotic fluid components ? They add that the "cell-free component of the amniotic fluid is discarded after these analyses and is therefore available for research and future clinical applications." Paige B. Larrabee, M.D., from Tufts-New England ......al for guiding surgical procedures. *Scans can be performed in a matter of a few minutes and because they are ultrasonic, they do not use potentially harmful ionizing radiation. *The system requires a minimum of special pre-scan procedures and appears likely, in clinical use, to be more comfortable for patie...Atmosphere may cleanse itself better than previously thought
...e breathing room." Francisco's research, which he performed at the University of California, San Diego with tw...m yet." The experiments, which Sinha and Matthews performed at UCSD, used a laser technique that allowed the team to look at the OH radical-producing molecules ...New miniaturised chip dramatically reduces time taken for DNA analysis
...ndreds, or even thousands, of genetic tests can be performed simultaneously with these chips, which are now a vital part of any large-scale project, such as unlocking the genetic code of an organism. DNA chips are limited to a certain extent because of some very specific analytical problems, such as establishi...UCLA cancer researchers shake loose hidden biomarker
...er has spread," he said. Rajasekaran and his team performed their research in prostate cancer cells lines and plan to validate their findings first in animal models and then in human clinical trials, which could be available in three to four years. Prostate cancer is expected to strike 232,090 men this year ...Cancer related gene p53 not regulated as indicated by previous tissue culture research
...netically engineered mice, the altered p53 protein performed flawlessly: it was unstable when no DNA damage was present and was stable and fully functional when needed to halt the cycle cell to repair DNA damage or to induce apoptosis. "It came as a complete surprise. We even used a system that would have all......ology graduate student in Arts & Sciences, has performed studies on mosquitofish (guppy-like fish, about an inch long) and found that female mosquitofish spend 80 percent more time with males who have a large gonopodium. "A male with a larger gonopodium has a higher chance of mating, but in a predator env...