Pennsylvania researchers find liver transplants provide metabolic cure for rare genetic disease
...lants on MSUD patients in May 2004. Children's has performed 18 MSUD liver transplants since then. The study by Children's and the Clinic for Special Children involved 11 of these MSUD patients, including the original patient. Results of the study are published in the March issue of the American Journal of Tr...A large step forward in the fight against African sleeping sickness
...carry out its neutralizing action. All the tests performed on mice have been very promising: Trypanosome-infected mice survive after 1 treatment. The parasite is removed from the blood and all effects associated with the disease disappear. There is every indication that this substance can also counteract Try...History of human cannibalism eats away at researchers
...eted her Ph.D. at the Universitat Pompeu Fabra and performed a substantial part of the sequencing work at DeCODE Genetics (Reykjavik, Iceland). ...Stem cell transplants improve recovery in animal models for stroke, cerebral palsy
...cal scenarios for stroke victims, transplants were performed seven days after the intitial injury. Currently, ischemic stroke patients may be treated with tPA, the only FDA-approved stroke treatment available, but must receive treatment within three hours from the time the stroke initially occurs. As a result...Healing honey: The sweet evidence revealed
... Extremity Wounds summarizes the data. Scientists performed 22 trials involving 2,062 patients treated with honey, as well as an additional 16 trials that were performed on experimental animals. Honey was found to be beneficial as a wound dressing in the following ways:...Secrets of the sea yield stronger artificial bone
...lacement and nearly 300,000 knee replacements were performed in 2000, according to the National Center for Health Statistics. These numbers are expected to swell in the future as baby boomers age. Because of the pressing need for longer-lasting artificial bone, researchers like Tomsia have developed materials...A case of mistaken molecular identity
... that under bright conditions, the Chagas patients performed comparably to 50 healthy control individuals. But in the dark, 37 of 45 (82 percent) Chagas patients had trouble seeing with at least one eye, and 19 of 45 (42 percent) had trouble with both eyes. Matsumoto then approached Paveto, and both contacted ...Inflammation and drugs to control this activity studied in a variety of tumors sites
.... The researchers analyzed 84 subsequent biopsies performed within five years in patients who had initially shown chronic prostate inflammation. In the follow up, 29 new cancer cases were diagnosed: six occurred in patients in whom initial biopsies showed only chronic inflammation, 15 in patients with initial...Predicting successful outcomes in living-donor liver transplants
...er function, specifically liver biopsies that were performed in 17 of the patients and liver scintigraphy (an i...e using a radioactive substance that is swallowed) performed on 18 patients. The ICG test however, had certain benefits. "This novel noninvasive method has advan...Plastic surgeons countdown first full facial transplantation
...r news of the first partial facial transplantation performed in France spread around the world, plastic surgeon...al transplantation will be a last resort procedure performed on carefully selected patients on a case-by-case basis." In the studies, doctors used cadavers to p...Experimental drug reverses key cognitive deficits, pathology in Alzheimer's
...ampus. The researchers found that the treated mice performed significantly better than untreated knockout mice on the task. Significantly, found the researchers, the poorer performance of the untreated mice resulted from their relative inability to remember from day-to-day the location of the platform. In an...First direct mechanical communication of mitochondria, cardiomyocyte nucleus shown
... in muscle session 486.6/board #C732. Research was performed by Allen Kaasik, Department of Pharmacology, University of Tartu, Estonia, who collaborates with Renée Ventura-Clapier and Vladimir Veksler of INSERM, University of Paris-Sud, France. Health Veksler said the team has been interested for many yea...Discovery may speed forest biotechnology
...h millions of years of separate evolution and also performed similar functions in aspen trees. To their surprise, however, the researchers found that the CO/FT combination also controlled the cessation of vegetative tree growth in the fall ?something that Arabidopsis plants, which die after a single growing s...Heat-shock protein vaccine reduces alveolar bone loss
...orea) today presented the findings of a study they performed to evaluate the bacterium Porphyromonas gingivalis heat-shock protein (HSP) 60 as a vaccine candidate to inhibit multiple bacteria-induced alveolar bone loss.Recombinant P. gingivalis HSP60 was produced and purified from P. gingivalis GroEL gene. Rat...Major obesity gene is 'lost in the shuffle'
...t no detailed investigation of ASIP has yet been performed in primates. With this in mind, Takafumi Ishida, Associate Professor of Biological Sciences at The University of Tokyo, and his colleague Kazuhiro Nakayama set out to compare the DNA sequences of the ASIP gene from various primates, including Old a...New MRI technique shows emphysema in asymptomatic smokers
...pecial kind of "hyperpolarized" helium before they performed two MRI tests of the lungs. Eleven of the voluntee...cant abnormalities compared to nonsmokers. CT was performed after MRI, to allow comparison between the two modalities. Even though CT is the more established mo...Synthetic molecule causes cancer cells to self-destruct
...d in three mouse models of cancer. The testing was performed in collaboration with William Helferich, a professor of food science and human nutrition at the U. of I., and Myung-Haing Cho at Seoul National University. The researchers also showed that PAC-1 killed cancer cells in 23 tumors obtained from a local ...Mitochondrial DNA sequencing tool updated
...ase. In the early 1980s, scientists in England performed the then-Herculean feat of sequencing the complete human mitochondrial genome. The genome consisted of 16,568 base pair, or units, of DNA and encoded 37 contiguous genes. But because of the balky sequencing tools of the day and their high cost, muc...How plants avoid feeling the burn
...th water and oxygen, so all measurements had to be performed in an environment that would both protect the mole...te was fast enough to match or exceed measurements performed in the plant system. One of the greatest challenges of the experiment came down to the human endura......ll and his colleagues at the University of Alabama performed the tests in roundworms; and co-author Jean-Christophe Roche and his colleagues at Purdue performed the tests in rat neurons. Caldwell is also coordinator of HHMI's Undergraduate Research Intern Progr...