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Tag: "peptides" at biology news

Mine runoff continues to provide clues to microbial diversification

... provided the ability to resolve and differentiate peptides that differ by as little as one amino acid. Nathan VerBerkmoes of the lab’s Chemical Sciences Division was instrumental in designing the experiments and acquiring the mass spectrometry data while Manesh Shah of the Biosciences Division provided th...

Natural antibiotics yield secrets to atom-level imaging technique

...erties of natural antibiotics called antimicrobial peptides (AMPs), which are produced by virtually all animal...years, they're still puzzling over exactly how the peptides wipe out bacteria and other microbes. Unlike conventional antibiotics, which typically inhibit speci...

Proteasome activator enhances survival of Huntington's disease neuronal model cells

...logging up with damaged proteins. When proteins or peptides mutate, they can present major problems to the clearing up of the intracellular environment. In Huntington's disease (HD) the disease provoking mutation in the huntingtin gene eventually causes the cell to build up intranuclear and cellular inclusion...

UCLA AIDS Institute researchers find a peptide that encourages HIV infection

...troviruses, could pave the way for the use of such peptides in gene therapy using HIV-based vectors as the delivery method. "Although it may seem counterintuitive to value or even study a peptide that increases the ability of HIV-1 to enter a broad range of human cells, retroviral vectors are currently bei...

Scientists identify prion's infectious secret

...n in real time. Tessier covered the array with peptides from baker’s yeast and then added prion protein to...me yeast species. He found that a small cluster of peptides recruited the prion proteins to misfold into an amyloid structure. This region of the protein, which...

UQ research heralds vaccine technology breakthrough

...back, if you like, the respiratory syncytial virus peptides into the vaccine." He hoped the vaccine would ultimately be able to protect people against both diseases in the one shot and, even better, the recombinant vaccine model could potentially be used for most infectious diseases and some cancers, Profes...

New designer lipid-like peptide with lipid nanostructures for drug delivery systems

... to understand the basic science of how lipid-like peptides interact with lipid molecules, but also may provid...pact of integrating short surfactant-like designer peptides in lipidic nanostructures. Anan Yaghmur, Michael Rappolt, Peter Laggner and Shuguang Zhang report...

In nature, proteins sweep up nanoparticles

...erhaps it’s a serendipitous accident. Proteins and peptides could be released by bacteria after they die, and are then scavenged by zinc sulfide. Or there could be a physiological reason. Perhaps the bacteria use the protein to sequester their sulfide waste product, which could otherwise accumulate and entomb...

Newly found sensing system enables certain bacteria to resist human immune defenses

...t itself by warding off attacks from antimicrobial peptides (AMPs), which are defense molecules sent by the body to kill bacteria. Bacteria are divided into two types, gram-positive and gram-negative, with the primary difference being the nature of the bacterial cell wall. Little is known about how gram-posi...

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