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Tag: "peptides" at biology news

Scientists identify 36 genes, 100 neuropeptides in honey bee brains

...ence, our behaviors. Understanding the roles these peptides play in the life of a honey bee will assist resear...ties of these neurons are influenced by the sea of peptides they are bathed in. "Neuropeptides undoubtedly play a role in the bees' shift from working in the ...

MIT creates 3-D scaffold for growing stem cells

...ny fragments of amino acids called self-assembling peptides to organize themselves into useful structures. Working with visiting graduate student Fabrizio Gelain from Milan, Zhang created a designer scaffold from a network of protein nanofibers, each 5,000 times thinner than a human hair and containing pores ...

Researchers discover key mechanism by which lethal viruses Ebola and Marburg cause disease

...derstanding the potency of these immunosuppressive peptides can be exploited to treat autoimmune diseases. ...

Worms produce surprise insight into human fever

...sis, low gut pH, lytic enzymes, and antimicrobial peptides to prevent microbial colonization of the intestine. In dissecting two conserved pathways required for C. elegans immunity to bacteria, Aballay found a wealth of data on innate immunity plus a surprising insight into another classic metazoan resp...

Motorola researchers develop selective sensors based on carbon nanotubes

...y, the researchers developed a method for applying peptides to single walled carbon nanotubes (SWNT) in field ... "Our sensor is based on the novel properties of peptides and carbon nanotubes," Tao explained. "Peptides can be used to recognize and detect various chemical...

MIT material stops bleeding in seconds

...ts called peptides, is applied to open wounds, the peptides self-assemble into a nanoscale protective barrier ...earchers applied the clear liquid containing short peptides to open wounds in several different types of tissue - brain, liver, skin, spinal cord and intestine....

Protein splicing upsets the DNA colinearity paradigm

...er person - when T lymphocytes recognize antigenic peptides displayed on the cell surface. The antigens are cr... the cell machinery that cut foreign proteins into peptides that are then displayed on the cell surface for recognition and destruction by CD8+ T lymphocytes. H...

New drug blocks influenza, including bird flu virus

...alities of the peptide were observed after similar peptides were found by Brandt and his colleagues to stop herpes simplex virus infection. ...

Tarantula venom and chili peppers target same pain sensor

...e researchers identified three protein subunits or peptides in the venom that targeted the receptor to cause p...r activated TRPV1, but they did not pinpoint which peptides were responsible. The fact that a second spider venom triggered a capsaicin receptor suggests tha...

Early-stage immune system control of HIV may depend on inherited factors

...wn to bind to those HLA types to see if particular peptides were more powerful in activating the HIV-specific CD8 response. The researchers found that, for many varieties of HLA, only a few HIV protein fragments were responsible for the activation of CD8 T cells early in infection. In addition, the sam...

Encouraging results in pancreatic cancer research

...vical and bone (osteogenic sarcoma) cancers. These peptides kill cancer cells that do not even contain native p53 protein and therefore appear to have a wide applicability in treating a variety of human cancers. ...

Decoy pill saves brain cells

...alcium-calpain feedback loop, treatment with decoy peptides might save some cells, Baudry said. His group plans to test the treatment in a stroke model in mice....

Buckyballs used as 'passkey' into cancer cells

... with pheylalanine as a link in their chain, these peptides did not pass through the cell walls. Barron's g...dren's Cancer Center, and found the Baa-containing peptides could mimick viral proteins and pass through the walls of cancer cells. The peptides were found effe...

Discovery of an HIV inhibitor in human blood points to new drug class

...rs sifted through a comprehensive library of small peptides that had been filtered from the blood of patients ...ity. After sorting the more than one million blood peptides into 300 fractions, they focused on one that blocked HIV without toxic effects on cells. Further ...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

... that do not respond to the drug. Recombinant peptides as biomarkers for cancer response to tyrosine kina...erbilt University are using a biomarker library of peptides to determine whether or not tyrosine kinase inhibitor therapy, combined with radiation therapy, is i...

Exploring the molecular origin of blood clot flexibility

...less stiff," explains Weisel. For example, various peptides or proteins, such as antibodies, bind specifically to fibrin, affecting clot structure. The idea would be to use such compounds in people to alter the properties of the clot, so it can be less obstructive and more easily dissolved. In the future, ...

Researchers from the UGR use a bacterium to obtain biopreservatives from food

...lgo points out that natural antimicrobial cationic peptides such as bacteriocins "represent a good alternative." Bacteriocins are proteins that are biologically active against members of the same species or species closely related to the producing bacterium. Some noteworthy bacteriocins those produced by l...

Cancer vaccines -- Taking a jab at cancer by stimulating the immune system

...rs, their vaccine uses three different p53-derived peptides to elicit responses from different aspects of immu...The three groups vary on whether the cytotoxic p53 peptides are delivered alone or in combination with a helper T cell-activating peptide that is either specifi...

Novel antigen-cloning technique may boost efforts to develop a melanoma vaccine

... "eaten," the phages, the B cells will express the peptides that are encoded by the cDNA library. The new process eliminates the need to transfer the HLA genes into recipient cells and match the genes to each T cell type as it permits the B cells to present the peptide to the T cells in context with their own...

Protein fragments sequenced in 68 million-year-old Tyrannosaurus rex

...ments, or peptides, 10 to 20 amino acids long. The peptides were passed over a liquid chromatography (LC) colu...he mass, specifically the mass-to-charge ratio, of peptides as they come off the LC column. To maximize his yield, Asara used an ion trap mass spectrometer, whi...

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