Could fungal collection hold the key to new life-saving drugs?
... over 28,000 strains, including Fleming’s original penicillin producing isolate. They will be supplying the University of Strathclyde’s Institute for Drug Research (SIDR) with extracts from filamentous fungi which will be screened to identify pharmaceutically active compounds, which could potentially be develo...Bacterial walls come tumbling down
... the sugar coating. The second step is targeted by penicillin and has been well studied. Although scientists ...resistant to several common antibiotics, including penicillin and amoxicillin, and is a great cause for concern among hospital infectious disease staff. Postdocto...Cocoa 'vitamin' health benefits could outshine penicillin
... found in cocoa, are so striking that it may rival penicillin and anaesthesia in terms of importance to public h... of medicine,' Hollenberg says. ‘We all agree that penicillin and anaesthesia are enormously important. But epicatechin could potentially get rid of 4 of the 5 mo...Turning green gunk to gold, anti-cancer gold
...ntial step in drug development. With drugs such as penicillin and tetracycline, it can easily be done, but cryptophycins present more of a challenge. Sherman's team realized that with all cryptophycins, the most difficult step came very late in the synthesis, at the point at which a key part called an epoxide--...Study shows antibiotic-resistant bacteria responsible for increase in muscle infections
...ave been treated by inexpensive antibiotics in the penicillin and cephalosporin family. Some years ago, strains resistant to these drugs, called methicillin-resistant Staphylococcus aureus (MRSA) appeared in hospitalized patients. Recently, however, newer forms of MRSA began to strike healthy people who have n...Cloning techniques produce FDA-approved antibiotic
...ions that have become resistant to the antibiotics penicillin and vancomycin. Fosfomycin is a member of a class of compounds called phosphonic acids because they contain a carbon-phosphorous bond. Fosfomycin functions by inactivating an essential enzyme involved in the formation of the bacterial cell wall. ...BGSU biologist trying to crack microscopic code
...ane is stabilized by a grid of sugar polymers, and penicillin wrecks the grid, making the cells susceptible to a body's natural defenses. Disrupting energy flow--knocking out the TonB and Tol systems--would provide another powerful weapon against disease-causing bacteria, he says, but researchers must first u...Study indicates dramatic rise in antibiotic-resistant community-acquired staph infections
...(MSSA), which can be treated by antibiotics in the penicillin or related groups (i.e, beta-lactam antibiotics). Previously, MRSA infections were usually restricted to hospital or healthcare-associated infections. This is clearly no longer the case. Henry M. Blumberg, MD, is the senior author of the study, ...Evolution follows few of the possible paths to antibiotic resistance
...form can serve to inactivate antibiotics including penicillin and cefotaxime. Analyzing how well each variant protected host Escherichia coli cells against treatment with various concentrations of antibiotic, the scientists found that only a very small fraction of these pathways confer ever-increasing resistanc...'Creationism is not science' ?making the case for Darwin at UCL
... you have an infection you need massive amounts of penicillin compared to that needed in the 1940s. The simple reason is that the bugs you are fighting have evolved." Commenting on whether this turn towards the Intelligent Design world view could hit the UK too, Professor Ruse (whose book The Evolution-Creatio...Penicillin, amoxicillin: Step aside for strep throat treatment
... it's time for long-time antibiotic stalwarts like penicillin and amoxicillin to step aside when it comes to the... percent of children treated for strep throat with penicillin ended up back in the doctor's office within three weeks of treatment. Children treated with amoxicil...Gaining ground in the race against antibiotic resistance
... the efficiency of a bacterial enzyme that renders penicillin and cephalosporin antibiotics useless. The results could lead to more effective enzyme inhibitors by giving drug designers a sneak peek at the next generation of resistance. Alejandro Vila, a Howard Hughes Medical Institute international research s...Hopkins AIDS experts issue warning about global efforts to provide drug therapies
...n 1922 and the mass distribution of the antibiotic penicillin in 1943. In the case of diabetes, insulin's avail...uests from the public. More controversial was the penicillin case, in which two government-appointed committees, one military and the other civilian, decided who...