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Tag: "penetrate" at biology news

Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily

...nity. Another protein — gp41 — then enables HIV to penetrate a T-cell membrane. Fusion takes place specifically...am found that FP-23 reduces the energy required to penetrate an artificial cell membrane by up to 13 fold, depending on the thickness of that membrane. “Reducin...

A new plant-bacterial symbiotic mechanism promising for crop applications

...recognition, thereby allowing the microorganism to penetrate inside the plant by the root hairs. The finding...he first observation was that the bacteria did not penetrate the roots of its host-plant by the hairs. It took advantage of “crack zones” comparable with wound a...

Bacteria ferry nanoparticles into cells for early diagnosis, treatment

...vehicles, harnessing bacteria's natural ability to penetrate cells and their nuclei, Bashir said. "For gene therapy, a big obstacle has been finding ways to transport the therapeutic DNA molecule through the nuclear membrane and into the nucleus," he said. "Only when it is in the nucleus can the DNA produce...

UCF nanoparticle offers promise for treating glaucoma

... barely 1-3 percent of existing glaucoma medicines penetrate into the eye, earlier experiments with nanoparticles have shown not only high penetration rates but also little patient discomfort. The miniscule size of the nanoparticles makes them less abrasive than some of the complex polymers now used in most e...

Iowa State scientists demonstrate first use of nanotechnology to enter plant cells

... chemists have successfully used nanotechnology to penetrate plant cell walls and simultaneously deliver a gene and a chemical that triggers its expression with controlled precision. Their breakthrough brings nanotechnology to plant biology and agricultural biotechnology, creating a powerful new tool for targe...

Hybrid molecule causes cancer cells to self-destruct

...t this is because the hybrid molecules more easily penetrate the surface of the cell than the individual chemicals. Once the components are inside, the researchers believe the partners help enzymes to resume the normal assembly of sugar molecules and correct aberrant gene expression patterns, two processes tha...

A genetic 'gang of 4' drives spread of breast cancer

...cancerous cells to escape into the bloodstream and penetrate through blood vessels into lung tissues. Although...sen up cells in capillaries, so that the cells can penetrate the lung tissue to grow there. "These findings provide a beautiful explanation for how the genes t...

Scientists discover how body fights to control spread of cancer

...ood vessel wall. The cancer cells then eventually penetrate the blood wall to form tumours at secondary sites. "The attachment of cancer cells to the blood vessel wall is one of the key steps in the spread of cancer. It has been known for a few years that galectin-3 concentration is significantly higher in ...

Cancer tip -- Nanoparticles can damage DNA, increase cancer risk

...ancer Research. Nanoparticles are small enough to penetrate cell membranes and defenses, yet they are large enough to cause trouble by interfering with normal cell processes, researchers at the University of Massachusetts say. Such nanoparticles are currently in use in electronics, cosmetics, and chemical ma...

Nanotechnology shows promise as next wrinkle fighter

... entered the cosmetic marketplace because they can penetrate deeper into the skin, transporting vitamins and other compounds to plump and smooth tissue. But Ilsoon envisions thin films that can be injected beneath the thinning outer layer of the skin, the epidermis, that over time stiffens and buckles with agi...

Can engineered immune cells stop AIDS?

...les in the body because they are naturally able to penetrate cells, inserting the genetic material they contain into their new host. By itself, a virus cannot reproduce; it must infect a cell and take control of the host's machinery to make copies. HIV also possesses an unusual structure and a keen ability ...

Ultrathin films deliver DNA as possible gene therapy tool

...ase the DNA. Large strands of DNA cannot normally penetrate cells, so Lynn constructs his films with special polymers designed to bundle the genes into small tight packages that cells can import. Once inside, the genes instruct the cells to make proteins. Lynn and his colleagues create the films one laye...

Cryoablation -- A new treatment option for some kidney tumor patients

...patients. Percutaneous ablation uses needles to penetrate the skin and deliver directly to the tumor either high-intensity, tissue-destroying heat through radiofrequency ablation, or freezing cold through cryoablation. Mayo Clinic’s radiologists are among the most experienced in the world in performing abl...

Math model predicts cancer behavior

... be lethal for the patient." A tumor that does not penetrate the surrounding tissue can often be surgically removed with curative success. "When a patient comes in with a tumor, we'd like to understand for that particular tumor, what are the chances that metastasis is going to occur," Quaranta said. "Does th...

Scientists design simple dipstick test for cocaine, other drugs

...ate to the edge of the membrane, which they cannot penetrate because of their large size. The aptamers quickly bind to any targeted molecules that are present, freeing some of the gold nanoparticles. The red-colored nanoparticles then migrate along the membrane, where they are captured by the streptavidin an...

U-M researchers use nanoparticles to target brain cancer

...n order for chemotherapy to treat a tumor, it must penetrate this barrier. Researchers tested the nanoparticles in cell cultures and animal models. The studies showed the nanoparticles traveled to the tumor, resulting in less Photofrin exposure throughout the body and enhanced exposure within the tumor. Th...

Report calls for improved monoclonal antibodies against solid tumors

...atments for solid tumors has been their ability to penetrate the tumor. To be effective, the treatment “must ga...ted the optimal antibody size, shape and charge to penetrate certain types of solid tumors. Researchers have also examined how antibodies, including monoclonal t...

Nanosecond-scale release of stinging jellyfish nematocysts

... drives nematocyst discharge, and that stylets can penetrate even thick crustacean shells. However, neither the... that generated by some bullets, and sufficient to penetrate the cuticle of crustacean prey. The researchers propose that the high speed of discharge is caused b...

Brain-computer link lets paralyzed patients convert thoughts into actions

...luntary movement, the motor cortex. The electrodes penetrate about 1 mm into the surface of the brain where they pick up electrical signals -- known as neural spiking, the language of the brain -- from nearby neurons and transmit them through thin gold wires to a titanium pedestal that protrudes about an inch ...

Combined treatment extends life expectancy for lung cancer patients

...h sends electrical current into the tumor, may not penetrate far enough into the lung to kill these areas of cancer. When the two therapies are combined, they complement each other. Thermal ablation kills the central tumor. In exchange, radiation kills the cells on the periphery of the tumor and elsewhere in...

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(Date:7/28/2014)... have a circulatory problem of the legs called peripheral ... require surgery in serious cases. This disease can lead ... amputation. , At The University of Texas Health Science ... non-surgical preventative treatment in a mouse model of the ... Their proof-of-concept study appears in the journal ...
(Date:7/28/2014)... professor John Essigmann and colleagues from the University of Washington ... if they could induce the virus to mutate uncontrollably, they ... a strategy that our immune system uses against many viruses. ... HIV to mutate at an enhanced rate, as expected. But ... small clinical trial reported in 2011. In a new study, ...
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