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Tag: "pediatric" at biology news

Research shows cord blood comparable to matched bone marrow

...this study, the investigators compared outcomes of pediatric leukemia patients who received unrelated bone marrow transplants with those who received umbilical cord transplants. While all bone marrow donors were matched, nearly all cord blood donors were mismatched. The main objective of the research was to...

Resistant HIV quickly hides in infants' cells

...Medicine at UCLA, noted that global elimination of pediatric AIDS will require not only prevention of mother-to... also development of new antiretroviral agents for pediatric use, particularly against highly resistant infection. "There is also a need for new and widely acces...

Thymus transplants gives hope to babies with fatal immune disease

...y is made, it is no longer a death sentence," said pediatric immunologist Louise Markert, M.D., Ph.D., who developed the procedure. "There is a treatment available -- thymus transplantation -- that has led to survival of most of the infants who otherwise would have died." For the procedure, surgeons obtain ...

NIAID expands capability for influenza research and surveillance

...d multiple U.S. states. St. Jude also will monitor pediatric populations for flu activity and maintain a surveillance component to monitor for evidence of the reemergence of the severe acute respiratory syndrome (SARS). Additionally, the researchers will explore strategies for controlling influenza outbreaks i...

Genetic fingerprints identify brain tumors' origins

... we need to consider when trying to understand how pediatric brain tumors form." Researchers use information...n recent years to link normal brain development to pediatric neuro-oncology, and these findings affirm that as a necessary approach," Gutmann says. "We won't ful...

Gene found for rare disorder may reveal new pathway in mental retardation

... study leader Ian D. Krantz, M.D., a specialist in pediatric genetics at The Children's Hospital of Philadelphia. Dr. Krantz and his co-author, Laird S. Jackson, M.D., of Drexel University College of Medicine, led the study team that announced the discovery of NIPBL, the first gene known to cause CdLS, in 2004...

Major gene study uncovers secrets of leukemia

...cted mutations that contribute to the formation of pediatric acute lymphoblastic leukemia (ALL), the most commo...overy not only suggests novel methods for treating pediatric ALL, but also provides a roadmap for the identification of unsuspected mutations in adult cancers. ...

MIT model helps researchers 'see' brain development

...veloping brains, provided by Ellen Grant, chief of pediatric radiology at MGH and the Martinos Center. Of the subjects scanned, eight were newborn, mostly premature babies ranging from about 30 to 40 weeks of gestational age, and three were from children aged two, three and seven years. Grant scanned these inf...

Infection detectives use disease 'fingerprints' to track common infections in children

... the way we do things," said Dr. Ramilo, who leads pediatric infectious disease research at UT Southwestern and Children’s. It could also prove useful for identifying previously unknown illnesses or biological weapons. "Even if we don’t know which pathogen it is, we still can tell which family or which ...

FSU researchers determine a critical factor in workings of proteins

...said. "For example, Wiskott-Aldrich syndrome, a pediatric genetic disorder characterized by eczema, immune deficiencies and low blood-platelet counts, can be traced to mutations on the Wiskott-Aldrich syndrome protein," Zhou said. "Normally, fast association of the protein with other biomolecules is critica...

Buckyballs used as 'passkey' into cancer cells

Scientists at Rice University and pediatric specialists at Baylor College of Medicine have dis...ren, and it is responsible for about 15 percent of pediatric cancer deaths," said Jianhua Yang. "Our findings are significant because neuroblastoma cells are wel...

Like salty food? Chances are you had low blood sodium when you were born

...d selecting the lowest. Each child underwent a pediatric physical examination. To estimate current sodium appetite, participants were tested for their preferred concentration of salt in soup and sugar in tea, followed by orally administered spray tests involving table salt and table sugar. Between the test...

Mutant gene causes severe kidney disease in infants

...." The discovery has important implications for pediatric nephrologists and pediatricians who treat infants with nephrotic syndrome, according to Hildebrandt. "In very early-onset nephrotic syndrome, it's important to find out if the child has mutations in PLCE1," says Hildebrandt. "Some infants with PL...

Gene therapy inhibits epilepsy in animals

...the lead researchers, Amy R. Brooks-Kayal, M.D., a pediatric neurologist at The Children's Hospital of Philadelphia and associate professor of Neurology and Pediatrics at the University of Pennsylvania School of Medicine. "This provides a 'proof of concept' that altering specific signaling pathways in nerve ce...

Studies look at how genes affect antipsychotic drug response

... weight gain in children ages 8-18 who suffer from pediatric bipolar disorder. An increase in prolactin (a pitu...alf of all atypical antipsychotic prescriptions in pediatric psychiatry. Adverse drug effects, such as weight gain and the possibility of prolactin elevation, ar...

Teenager moves video icons just by imagination

..." said Moran, who said the team plans to test more pediatric subjects. "No one has ever seen if brain signals from children are different. We'll try to determine if teenagers have different frequency distributions when their cortex becomes active. We might question if the frequency alterations are different, w...

Artificial cornea offers better results for infants, some blind patients

... at the Cornea Society meeting in Las Vegas, while pediatric ophthalmologist Matthew Gearinger, M.D., of the Eye Institute is presenting at AAO. The study overall included 23 separate procedures on 17 patients; most of the procedures were performed by Aquavella in Rochester, while four were done by Esen K. Akp...

Three-dimensional, miniature endoscope opens new diagnostic possibilities

...fallopian tubes and the pancreatic duct. Fetal and pediatric procedures may also benefit from this tool. Eventually, SEE could give rise to new procedures that permit diagnosis and microsurgery in previously inaccessible areas of the body." ...

Getting to the heart of the heart

...d Medical School and also chairs the department of pediatric oncology at Dana-Farber Cancer Institute. He and Wu are also members of the Harvard Stem Cell Institute. "Previously, it had been thought that each cell type in the heart had a different origin. Now, it's pretty clear that some have common origins,...

Bacterial protein shows promise in treating intestinal parasites

...at a parasitic nematode." Aroian met Cappello, a pediatric infectious diseases specialist who studies hookworm, at a meeting of the Burroughs-Wellcome Fund and decided to collaborate on a project to see if crystal proteins could be effective against hookworm infections. Three years ago, Aroian and his colle...

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