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Tag: "payload" at biology news

Image of myosin-actin interaction revealed in cover story of Molecular Cell

...ne direction using actin as a track to deliver its payload of cell vesicles and organelles. Myosin V is also involved in transporting proteins that signal and communicate with other cells. Myosin V has a two-chained "tail" that diverges to form two "heads" that bind to specific grooves on actin and walk h...

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

...nternalised making it possible for their cytotoxic payload to get released directly inside the cancer cells. ...to the targeted cells ?an important fact since the payload of nanoparticles may be released inside the cancer cells in a regulated manner over an extended peri...

Researchers use 'trickery' to create immune response against melanoma

...nternalised making it possible for their cytotoxic payload to get released directly inside the cancer cells. ...to the targeted cells ?an important fact since the payload of nanoparticles may be released inside the cancer cells in a regulated manner over an extended peri...

Nanotechnology may find disease before it starts

...ize, nanoparticles are still big enough to carry a payload of medicine, Rosol said. "That the particles made it into the liver suggests that they could be used to deliver toxic chemotherapeutic drugs that would act locally on a tissue, at the site of a tumor, and not have such a pronounced affect on the res...

Research details how a virus hijacks cell signals to cause infection

...r into cells where it can release its nucleic acid payload and complete the process of infection. "We showed for the first time that this virus is dependent on signaling pathways to drive invasion," said Dr. Bergelson. Specifically, the coxsackievirus activates kinases, enzymes that are instrumental in mov...

How sperm crack the whip

...anism by which the sperm head delivers its genetic payload to the egg, he said. Such research could yield insight into some male infertility, said Clapham. Still-unidentified mutations in any of the four CatSper proteins ?all of which are involved in motility ?could underlie some forms of infertility, he s...

UF scientists test improved gene therapy method for hereditary heart conditions

...lso delivering a significant amount of its genetic payload to the liver and to other muscles. Because AAV-9...at determines where the truck is going to take its payload to." "Laboratories are engineering new ZIP codes onto these vectors so they can try to control whe...

Scientist-astronaut sends T-cells into space

... of the U.S. Department of Veterans Affairs, and a payload specialist aboard space shuttle flight STS-40 in 1991, will send human T-cells up to the International Space Station aboard ISS Soyuz 13. That science mission, operated by the European Space Agency, is scheduled to launch from Baikonur between Septem...

Microscopic passengers to hitch ride on space shuttle

...nter, Moffett Field, Calif., developed the Microbe payload for flight. According to scientists, understanding human biological changes and microbial responses while living in enclosed quarters in space is important to the health, safety and performance of crewmembers and requires further study. The flight ...

Buckyballs boost antibody's chemotherapy payload

...uckyballs might be used to significantly boost the payload of drugs carried by tumor-targeting antibodies. I... no covalent bonds were required, so the increased payload did not significantly change the targeting ability of the antibody. Wilson said certain binding sit...

K-Staters design and build a low-cost remote sensing tool for environmental studies

...low" just a few feet above the ground. The onboard payload of digital cameras, spectral radiometers and other remote sensing instruments will produce high-resolution images and data about small groups of plants and their environmental stress level. At just 15 pounds with payload, the bantamweight hobby airf...

Interfering RNA silences genes in 'slippery' immune cells

...ll nucleus. Into the nucleus, researchers insert a payload of DNA. The DNA holds a sequence of genetic code that produces a specific siRNA after it enters a nucleus. The researchers encased the DNA within an siRNA expression cassette (SEC), an inexpensive, quickly synthesized product that carries genetic s...

Climate experts search for answers in the oceans

...ceanographic services. Sentinel-3, whose principal payload is an ocean-monitoring altimeter and an optical and infrared radiometer, is scheduled for launch between 2011 and 2012 as part of the Global Monitoring for Environment and Security (GMES) service....

U-M researchers use nanoparticles to target brain cancer

... tumor vasculature with nanoparticles containing a payload will overcome these issues," says study author Alnawaz Rehemtulla, Ph.D., professor of radiology and radiation oncology at the U-M Medical School and professor of environmental health sciences at the School of Public Health. Treating brain tumors...

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