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Tag: "patterns" at biology news

MiRNA fingerprint identified in platelet formation

...sly uncovered substantial evidence linking certain patterns of miRNA to both normal and abnormal blood cell de...megakaryoctyes. They also studied miRNA expression patterns in four acute megakaryoblastic leukemia (AMKL) cell lines. They discovered that a set of 17 miRNAs...

Cuttlefish masters of disguise despite colorblindness

...ttlefish are known to have a diverse range of body patterns and can switch between them almost instantaneously. New research from MBL Marine Resources scientists, to appear in the May 2006 issue of the journal Vision Research, confirms that while these masters of disguise change their appearance based on visu...

Stanford/Packard scientist's data-mining technique strikes genetic gold

...iments allow researchers to compare the expression patterns of tens of thousands of individual genes over time in diseased and healthy cells, or in many other experimental conditions. Each experiment generates thousands of pieces of data about the cell's genes. Although biologists use the technology routinely...

Predicting chemotherapy outcome

...e, used microarrays to analyse the gene-expression patterns of samples from colon tumours and liver metastases collected from 13 patients with colorectal cancer. The microarray analyses were carried out before the patients were treated with combined chemotherapy of folinic acid, 5-fluorouracil and irinotecan....

For some young fish, early gene expression is a clear harbinger of fated lifestyle

...ly related genetically show dramatically different patterns of actual gene expression if they have adopted dif...erent populations nonetheless exhibit very similar patterns of gene expression if they have adopted the same fate--residential or migratory. Thus, the researche...

Key heart and Alzheimer's disease protein imaged for first time in native state

...e of a molecule by analyzing the x-ray diffraction patterns of crystals that make up the molecule. "The next step is higher resolution, going from the current 10 angstroms to 3.5 or better," adds Weisgraber, who is also a professor of pathology at the University of California, San Francisco. Lipid-bound ...

Cracking the genetic code for control of gene expression

...pressed in tightly controlled spatial and temporal patterns but we do not know the code by which the expression is regulated. In this post-genomic era, the next big goal is to decipher the genetic code of regulation of gene expression. At the University of Helsinki the researchers have been interested in seq...

Penguins waddle but they don't fall down, UH researchers say

...es of penguins. Next, he will examine the running patterns of the penguins. And if you think penguins are cute waddling, just wait till you see them in a hurry. As comical as his subjects may be, Kurz remains a scientist first and an amused spectator second. "You can't help smiling," Kurz said, "but th...

St. Jude projects 90 percent cure rate for ALL

...are so important. They let clinicians identify the patterns of gene activity and inactivity in both the patient's body and in leukemic cells that influence drug efficacy and toxicity. Without such information we would still be treating ALL using a lot of guesswork instead of good science." Pharmacogenomics i...

Medieval diaries aid scientists ascertain increase in hot spots due to global warming

...nd the Rockies, which had been cored to reveal the patterns of wide and narrow tree rings over time - wider rings relating to warmer temperatures. Ice from cores drilled in the Greenland ice sheets revealed which years were warmer than others by the chemical composition of the ice. They also used a record ...

Oops! Researchers publish new findings on the brain's response to costly mistakes

... certain aspects of everyday life, with repetitive patterns of behavior to ward off or prevent such events. The new research, published in the Journal of Neuroscience, involved 12 healthy adults who had their brains scanned using a powerful functional MRI (fMRI) imaging machine, while they were asked to res...

Viral 'fitness' explains different resistance patterns to aids drugs

...ing how virologic fitness determines how different patterns of taking medications may lead to resistance" said Steven Deeks, MD, associate professor of medicine at UCSF's Positive Health Program at SFGHMC and senior author on the study. Both NNRTIs and non-boosted protease inhibitors are potent antiretrovira...

Face perception is modulated by sexual orientation

...ers. Thus, it is reasonable to assume differential patterns of activation in the hetero- and homosexual brains...sexual preference, also showed virtually identical patterns of neural activation in regions in the visual cortex and the limbic system, where male and female fa...

Paleontologists learn how not to become a fossil

...and the role of humans in bringing about change in patterns of life on Earth, said Kidwell, the William Rainey...ailable data, but check to see if the evolutionary patterns they detect are consistent with the distortion of the fossil record. If the patterns run counter to ...

Berkeley researchers lay groundwork for cell version of DNA chip

...s ill-suited for applications that require precise patterns of multiple cell types. The authors behind the Angewandte Chemie paper have solved the problem with the creation of a highly selective cell adhesion system that uses single-strands of synthetic DNA to fasten the cells to a surface. This enables dif...

Poison dart frog mimics gain when birds learn to stay away

...own because predators would stop associating color patterns with toxicity.) If the mimics looked like the mor...t mimics can actually be freed to evolve new color patterns and that this could also explain why poison frogs are so diverse. "When predators generalize, it ac...

Genome changes tracked during multiple myeloma initiation, progression and treatment

...suppressor genes. These amplification and deletion patterns define new disease subgroups of MM that are characterized by varied dysregulation of distinct cancer-relevant genes and can be correlated with different clinical outcomes. Importantly, several candidate genes identified in this study possess broad cl...

Most human-chimp differences due to gene regulation ?not genes

...mes as likely to have changed their own expression patterns as the genes they regulate. Because they influence the activity of many "downstream" genetic targets, small changes in the expression of these regulatory genes can have an enormous impact. "When we looked at gene expression, we found fairly small ...

Scientists discover new genetic subtypes of common blood cancer

...e human faces plucked the four distinguishing gene patterns out of a landscape of many DNA alterations in the .... Four distinct myeloma subtypes based on genetic patterns emerged: Two of them corresponded to the non-hyperdiploid and hyperdiploid types, and the latter was...

Aging cells, aging body: Fresh evidence for a connection

...urther TIF research, I am eager to see if the same patterns play out in other tissue." Brown post-doctoral research fellow Utz Herbig is the lead author of the article. Brown undergraduate Mark Ferreira rounds out the Brown research team. Laura Condel and Dee Carey from the Southwest Foundation for Biomedica...

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