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Tag: "patients" at biology news

Sunshine pill for prostate cancer in 2009

...ar (DN-101), is based on vitamin D and is given to patients in the advanced stages of prostate cancer along wi...gnificantly improved survival rates, 9 months over patients taking chemotherapy drugs (taxotere) alone. 'On average, patients in the advanced stage of the dise...

Stem cells decrease ischemic injury and restore brain function

... recent advancements in the management of ischemic patients (early diagnosis, thrombolysis, stroke units and rehabilitation centers), stroke still represents a major and unresolved medical issue. "Stroke causes the death of many nervous cells that, in theory, could be substituted by stem cells. A few stud...

Molecular signature may identify cisplatin-sensitive breast tumors

...basis of this sensitivity, which may help identify patients most likely to benefit from cisplatin treatment. ...erceptin nor antiestrogen drugs, the prognosis for patients with the tumors has been poor. Triple-negative tumors are the most common subtype found in patients...

Scientists discover a new risk factor for Alzheimer's

...wing reduced SORL1 protein levels in the brains of patients with Alzheimer's. Then we have the observation by us and other groups that if you reduce SORL1 expression--in either cell cultures or mice--you get an increase in the production of amyloid-beta. Now we can add our new observation that variants of the...

Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer

... delivered into the tumors of stage 4 lung cancer patients via an intravenously administered lipid nanoparti...-small cell lung cancer tumors. "We've treated 13 patients in this first-in-human study and we've seen an exciting proof of concept with no significant drug-r...

Swell gel could bring relief to back pain sufferers

...This development opens up the possibility of human patients being able to regain full mobility and flexibility after receiving spinal injections. This would compare favourably with spinal fusion - a major surgical procedure with considerable recovery time for the patient, resulting in a significant loss of...

Napoleon's mysterious death unmasked, UT Southwestern researcher says

...histicated surgical techniques and chemotherapies, patients with gastric cancer as advanced as Napoleon's have...were no tumors in other organs. Only 20 percent of patients with Stage IIIA gastric cancer survive five years if treated with modern surgery and chemotherapy. ...

Researchers discover genetic cause for word-finding disease

... their hobbies and perform other tasks. "One of my patients redid his vacation home and rebuilt all the cabine...turing and one kept up her organic garden. We have patients who do very complicated things even when they can't put two sentences together," Mesulam said. Alzhe...

Cancer researchers add spice to research against rare neuromuscular disease

... 40s, and while most live a normal life span, many patients end up using a wheelchair and have serious health difficulties. Currently there is no way to slow the progression or prevent the disease, which is estimated to affect a few thousand Americans, perhaps 4,000 or so. In the experiments reported in Na...

Lab research may one day lead to cancer treatment using patient's own immune cells

...g to Kim, the Phase I study would involve about 20 patients and would open in about five years. "If these tri...ccessful, a similar approach could be developed in patients with other types of cancer as well," said Kim. ...

Researchers uncover protection mechanism of radiation-resistant bacterium

...of radiation; could lead to ways to protect cancer patients from the toxic effects of radiation therapy; and may prove significant in efforts to contain toxic runoff from radioactive Cold War waste sites. Fifty years ago, scientists discovered D. radiodurans, leading to speculation that the incredible degr...

Discovery of an HIV inhibitor in human blood points to new drug class

... peptides that had been filtered from the blood of patients with chronic kidney failure during dialysis, in search of those with anti-HIV activity. After sorting the more than one million blood peptides into 300 fractions, they focused on one that blocked HIV without toxic effects on cells. Further examina...

Computer imaging assists with facial reconstructive surgery

...hotograph analysis and medical record review of 14 patients (average age 32, 12 females and two males) who und... medical center between 1999 and 2004. Six of the patients received implants in their chins, while eight underwent a procedure known as osseous genioplasty, in...

Parasite infection may benefit MS patients

...l Research in Buenos Aires, Argentina, involved 12 patients with MS who also had a parasite infection, 12 cont..., and 12 healthy individuals. The two groups of MS patients had a similar disease course. Patients had a neurological exam every three months and a brain MRI ev...

Protein found to shield pancreatic cancer cells from self-destruction

...vel and potentially effective approach to treating patients with pancreatic cancer," Lopez-Berestein said. Research in the mouse model remains in the early stages, the researchers caution. The researchers also show that the TG2 pathway also is separate from another, better known, form of programmed cell de...

Long-term narcotics use for back pain may be ineffective and lead to abuse

...are used despite the concerns clinicians have with patients developing an addiction to these medications," sai...ence and effectiveness of opioid prescriptions for patients with chronic back pain, and the incidence of substance abuse disorders among patients receiving opio...

Active ingredient in common Chinese herb shown to reduce hypertension

...f they fail, medications are prescribed. Many patients with high blood pressure have sought relief from complementary and alternative medicine (CAM). In so doing, many have consumed danshen, a Chinese herb used in Oriental medicine that promotes blood flow and treats cardiovascular disease. Tanshinon...

Brain networks strengthened by closing ion channels

...n and behavior. ADHD is highly heritable, and some patients with ADHD may have genetic changes in molecules th...mally regulates cAMP. Loss of function of DISC1 in patients with schizophrenia or bipolar disorder would increase vulnerability to cortical network disconnectio...

Severe mental retardation gene mutation identified

...." X-linked mental retardation is severe. Some patients require total care and may not have language ability. The condition runs in families and only affects the male offspring. So far only a few of these genes have been identified. Working through a large, international collaboration, the research...

Knocking out survival protein could aid leukemia treatment

...ucted this research using cancer cells from 17 CLL patients and ALL cell lines grown in the laboratory. Th...e effect was the same even in cells that came from patients with advanced cancer or from patients with tumors that resisted conventional treatment. When the...

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