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Tag: "patient" at biology news

Bioartificial kidney under study at MCG

...nistration, it likely would be used as long as the patient is in failure. Kidneys require a lot of oxygen and energy to perform their endless task, which makes them easy targets in the ICU, Dr. Szerlip explains. As examples, kidneys can become ischemic and begin to fail if blood pressure drops because of a ...

Jump-starting T Cells In Skin Cancer

...cinated with a tumor antigen called MAGE-3. In one patient whose tumor regressed after vaccination, the authors found significantly more T cells specific for non-vaccine tumor proteins than were detected before vaccination. Vaccine-specific T cells, on the other hand, became detectable but did not expand to ...

Protein discovery could unlock the secret to better TB treatment

... of methods to 'wake-up' all dormant bacteria in a patient allowing antibiotics to kill the bacteria and cure the disease." The team includes Prof Brian Henderson at the UCL Eastman Dental Institute, Nicholas Keep from Birkbeck, University of London, and John Ward at UCL as well as researchers from INSERM M...

W.M. Keck Foundation funds study of friendly microbes

...tive, which aims to translate genomic science into patient care. The CGS plays a catalytic role in helping to devise new ways to translate the genetic data obtained from genome sequencing projects to allow researchers to better understand the evolution and diversity of life on Earth, as well as help create n...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...m culture in heat-inactivatedserum from the actual patient who is going to receive the therapy, thescientists said. However, it may still prove difficult to completelyeliminate the Neu5Gc, because is has become metabolically incorporatedinto the currently available, federally-funded human embryonic stemcell ...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...and protein markers that can predict whether a CLL patient will follow the benign or aggressive course. Some markers are not yet available for clinical use, however according to the review, measurement of one protein marker called ZAP-70 is becoming more widely available. The authors note that ZAP-70 may act...

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

...certain cancers,classifying tumors, and predicting patient outcome. So far, though,microarray studies have be...usassociation between gene expression profiles and patient outcome.This project is also an example of NCI interest in developingpublic/private partnerships. Af...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

...rough when performing medical exams, and in taking patient histories to be alert for signs of heart rhythm di...earing of a case of heart rhythm disturbances in a patient taking protease inhibitors, the researchers looked for evidence of other patients with similar exper...

U-M scientist to talk about tissue engineering at AAAS

...e and contours of natural bones. That would help a patient develop new bone almost indistinguishable from nature's original equipment. Many researchers at University of Michigan have focused their tissue engineering efforts on the head and neck, in part because U-M Dentistry plays a leading role in the effo...

Genome-wide mouse study yields link to human leukemia

... and the findings offer important implications for patient care, since we know that methylation, which alters gene function, can be reversed," says Christoph Plass, senior co-author and a member of the OSUCCC's Molecular Biology and Cancer Genetics and Experimental Therapeutics Programs. While it was Caligi...

Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa

...se, a strong research component and an established patient base of degenerative retinal diseases, we were able to be a part of this important study." Pre- and post-surgery patients are evaluated by a team of researchers working at the Eye Center and the VA Rehabilitation R&D Center including Ronald A. S...

Gene therapy converts dead bone graft to new, living tissue

...e is then literally screwed into place, giving the patient most of the strength and support of the original bone. Bone, unlike any other tissue in the human body, can still perform one of its functions, structural support, even if all its cells are completely dead. A serious problem arises, however, when the...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

...response. "This is an important issue in terms of patient quality of life. Do you want to go through seven weeks of treatment only to find two months later that it had no effect? Using MRI tumor diffusion values to accurately predict the treatment response early on could allow some patients to switch to a m...

Gene variations explain drug dose required to control seizures

...etermine because of the drug's variable affects on patient metabolism and its potential neurologic side effec... may be of particular importance for understanding patient response to drug treatment, said the researchers, noting that many other anti-epilepsy drugs act on ...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...n gene therapy, a therapeutic gene is delivered to patient cells, often using a modified virus. Gene therapy might offer an alternative treatment for those children who fail to respond to enzyme replacement therapy, he said. Even for those that respond well to enzyme infusions, treatment requires weekly inj...

Genetically modified natural killer immune cells attack, kill leukemia cells

...se modified NK cells will then be infused into the patient after the transplant in order to eliminate residua...her application, NK cells could be obtained from a patient while in remission and then reinfused after genetic modification if the patient suffers a resurgence...

Placenta Is A Rich Source Of Blood Stem Cells

...ealth care grounded in the values of excellence in patient care and sensitivity to the complex needs and diversity of children and families. Children's also is the primary pediatric teaching affiliate of Harvard Medical School. For more information about the hospital visit: http://www.childrenshospital.org/r...

Potential Cure for Lymphoma in HIV patients

...logous transplant, stem cells are removed from the patient andfrozen for later use. The patient receives high-dose chemotherapy tokill any lymphoma in the body, and the autologous stem cells are t...

HIV Infection Still On The Rise

...red abroad. Furthermore, each newly diagnosed HIV patient consumes £12,500 in healthcare costs each year, while the lifetime costs of care for the current 50,000 infected individuals in the United Kingdom, with a life expectancy of 20 years, is at least £12.5bn. "Prioritisation of sexual health with substa...

New SARS Protein Linked To Important Cell Doorway

...c information to rapidly advance possibilities for patient treatment. If further investigation shows orf7a is important to the SARS virus' ability to cause disease, scientists will already have much of the knowledge they need to develop ways to disable or weaken it. "The key to studying novel viruses used t...

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