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Tag: "pathways" at biology news

Wisconsin scientists grow critical nerve cells

...come spinal motor neurons, critical nervous system pathways that relay messages from the brain to the rest of the body. The new findings, reported online today (Jan. 30, 2005) in the journal Nature Biotechnology by scientists from the University of Wisconsin-Madison, are important because they provide critic...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

...ries out basic research on fat cells and metabolic pathways in diabetes and cancer at Dana-Farber. "It offers ...many key genes of lipid biosynthesis involving the pathways of cholesterol and triglycerides; these genes directed the liver to manufacture more cholesterol, wh...

New binding target for oncogenic viral protein

...emely important tool in understanding the cellular pathways that regulate cell division and are disrupted in c...es cell division may lead to new insights into the pathways that cause cancer. This is an important step to designing new cancer treatment strategies that targe...

Fox Chase Cancer Center scientists identify immune-system mutation

...e, they are proving to be useful for exploring the pathways of lymphocyte development, according to Kappes. H... to class I MHC. However, the underlying molecular pathways that regulate this process have remained obscure. "The mutant HD mice are unable to generate mature...

NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis

... to the protective effect of interferons, inducing pathways to fight the virus' spread. However, their findings showed that interferons fight the virus at different stages of the virus' life cycle. First, they inhibit viral RNA and protein synthesis. If this fails, interferons block the virus from forming par...

A bacterial genome reveals new targets to combat infectious disease

...ies. Slatko and colleagues enumerate a variety of pathways that have either been degraded or preserved, and highlight patterns in the genome structure through comparisons with other bacteria. For example, Wolbachia can manufacture some essential metabolic coenzymes, which do not appear to be made by its host...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

.... This indicates a different mixture of cell death pathways within the tumors. In the end, any change is good. When you think about it, if the treatment is not having an effect, the tumor will continue to grow without any change to water diffusion," Ross said. The researchers found that for each of the 20 pa...

Poplar trees redirect resources in response to simulated attack

...o see how it is allocated into various biochemical pathways is an incredibly powerful tool for learning how plants cope with stress," says plant scientist Michael Thorpe who is helping to build the plant-imaging program at Brookhaven. Plants subjected to the jasmonic acid "attack" produced more radiolabeled ...

In the sea slug's defense against lobsters, confusion is key

...d these chemicals serve to activate nervous-system pathways that control feeding behaviors of the lobster. The inky secretion also stimulates other behaviors in the lobster, including grooming and avoidance. Ironically, the slug's ability to trick the lobster's nervous system into activating feeding-associate...

UCSD researchers maintain stem cells without contaminated animal feeder layers

...llular events will help to unravel the biochemical pathways responsible for 'stemness'. An increased efficiency in the generation and culture of human stem cells for potential clinical applications is timely, given the recent report of 17 newly derived stem cell lines available for non-federal research. The f...

Alcohol's effects on gene expression in the central nervous system

...tral tegmental areas show that distinct biological pathways are associated with alcohol's action in specific b...anges in gene expression in very discrete neuronal pathways that may be involved in mediating the effects of alcohol that lead to addiction," he said. "Future s...

PANTHER Protein Classification System Database 5.0

...erred biological functions and explore morethan 60 pathways associated with protein families, subfamilies, and...d by Dr. Kitano’s group was usedto draw all of the pathways available on the PANTHER system Web site,which provides sufficient molecular detail of the pathway d...

Agilent Technologies releases automated literature search tool for biology researchers

...works, increasing their understanding of molecular pathways and the biological causes of disease. The Agilent Literature Search tool automatically searches for and extracts information from multiple textual databases, such as those of the U.S. Patent Office and the National Center for Biotechnology Informati...

The Bacteria's guide to survival

...orrhoeae type IV pilus stimulates mechanosensitive pathways and cytoprotection through a pilT-dependent mechanism. PLoS Biol 3(4): e100. ...

Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits

...re were 183 protein clusters and 240 communication pathways conserved in all three. The finding suggests that ... percent of the protein clusters and communication pathways are conserved in the three species, but Ideker estimated that as many as 80 percent of the actual pr...

VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain

...end impulses to one another more effectively. Such pathways showed different responses to alcohol in one mouse strain versus the other. As a result, Miles and his colleagues were able to formulate new hypotheses about how the brains of the mouse strains responded differently to alcohol. An additional pathway...

How an AIDS-Related Cancer Unleashes Inflammation

...g the protein VEGF. The activation of angiogenesis pathways by kaposin B fits with observations made in patients with KS, Ganem noted. "If you examine lesions in a patient with KS, you'll see that they are visibly red because of all the new blood vessels that KS produces," he said. In cell culture studies, t...

Antibiotic might fight HIV-induced neurological problems

...ered that SIV triggers some of the same biological pathways of cell death and inflammation as these other dise...nocycline "calms down" as yet undefined biological pathways that involve two specific proteins -- MCP-1 and p38 -- implicated in damage in neurodegenerative dis...

NYU study reveals how brain's immune system fights viral encephalitis

... to the protective effect of interferons, inducing pathways to fight the virus' spread. However, their findings showed that interferons fight the virus at different stages of the virus' life cycle. First, they inhibit viral RNA and protein synthesis. If this fails, interferons block the virus from forming par...

Hirsute Or Hairless? Two Proteins May Spell The Difference

... During the budding process, overlapping signaling pathways from two adjacent embryonic cell layers—the epithelium and the mesenchyme—direct morphogenesis. The mesenchymal cells initiate the cell-to-cell “crosstalk?that controls bud formation by first directing a small cluster of epithelial cells to form a pl...

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