Creation of antibiotic in test tube holds promise for better antibiotics
...well against Gram-positive bacteria and food-borne pathogens that cause botulism and listeriosis because it punches holes into cell membranes and binds to essential molecules in the disease-causing bacteria. Hitting on at least two targets reduces the risk of resistance occurring, van der Donk said. The resea...Virginia Bioinformatics Institutes launches microbial database
... genome sequence and annotation data for the plant pathogens Phytophthora sojae and Phytophthora ramorum. The p...e the recently completed genome sequences of these pathogens as well as powerful analytical tools widely available to researchers in one integrated resource. The...Gene thwarts some pathogens, gives access to others, could save crops
...na identified the gene that helps plants recognize pathogens and also triggers a defense against disease. The g...vade. "This gene, BIK1, makes plants resistant to pathogens such as Botrytis, but it allows biotrophic pathogens to invade," said Tesfaye Mengiste, a Purdue pla...HIV vaccine takes different tack to boosting immune response
...herapeutic and prophylactic vaccines against other pathogens in addition to HIV. Drs. Xiao-Tong Song and Kevin Evel-Kabler, both postdoctoral associates at BCM's Center for Cell and Gene Therapy, also contributed to the study. ...New method enables gene disruption in destructive fungal pathogen
... may also find applications in the study of fungal pathogens that directly impact humans and human health. In addition to causing numerous plant diseases, Alternaria are involved in the development of such chronic airway diseases as asthma, allergy and chronic rhinosinusitis. Gene disruption methods could help...Newly discovered killer cell fights cancer
...this one cell combines the ability to kill foreign pathogens and distribute information about that experience," says Drew Pardoll, M.D., Ph.D., the Seraph Professor of Oncology at the Johns Hopkins Kimmel Cancer Center. "We think this hybrid cell speeds up immune reactions and makes the system more efficient...New method for identifying microbes
...seful for cleaning up contamination to identifying pathogens and distinguishing harmless bacteria from potential bioterror weapons. "Microbial communities are enormously diverse and complex, with hundreds of species per milliliter of water or thousands per gram of soil," said Brookhaven biologist Daniel (Niel...APS lecturer shows rare video of 'teacher-student' immune cell interactions in live animal
... effector sites elsewhere in the body to eliminate pathogens or tumors, but also may cause inflammatory disease... heart of any vaccination," von Andrian said. Many pathogens take advantage of the lymph system to gain access to the body, he noted, including pathogens used in...Single cell amoeba increases MRSA numbers 1000- fold
...nd digests environmental bacteria. It also engulfs pathogens such as MRSA. However, instead of being digested by the amoeba, MRSA survives and replicates whilst inside the amoeba. Prof Michael Brown and colleagues at the University of Bath, found that MRSA in association with amoebae increased in numbers 1000-...Malaria, potato famine pathogen share surprising trait
Two wildly different pathogens ?one that infects vegetables, the other infecting ...e ?mostly young African children ?and Phytophthora pathogens devastate a wide range of food and commercial crops. The researchers swapped a small sequence of p...Purdue creates new low-cost system to detect bacteria
...g stem cells to drug-resistant staph infections to pathogens on the battlefield." said J. Paul Robinson, a researcher at the Bindley Center and a professor in the Weldon School of Biomedical Engineering and the School of Veterinary Medicine. The work was initiated by Arun Bhunia, a professor of food microbio...DNA: Bacteria's survival ration
...dy may be sustaining harmful bacteria. One of the pathogens implicated in cystic fibrosis is suspected of feeding on DNA in lung tissue, Finkel said. Biofilms, which have been linked to chronic infections, also may harbor nutritionally competent germs. If researchers succeeded in turning off nutritional comp...Researchers add crucial information on how the body's T cells react to parasitic diseases
...ding the targets of the T cell response in complex pathogens such as T. cruzi requires much more. Scientists must integrate information generated from the recent analysis of the T. cruzi genome and proteome, with bioinformatics and cutting-edge techniques like advanced flow cytometry to unravel what is happeni...Radiation-killed bacteria vaccine induces broad immune response in mice
...thus unable to cause illness, irradiated bacterial pathogens evidently retain characteristics that prompt the i... study's lead author. "In this respect, irradiated pathogens more closely mimic the body's response to a live, attenuated vaccine." Finally, the scientists f...Microbes hitchhike across Atlantic on desert dust
...ector to renew reservoirs of some plant and animal pathogens in North America and could also be the cause of new diseases," says Griffin. ...Microscopic passengers to hitch ride on space shuttle
...bedside by providing a better understanding of how pathogens cause disease that will lead to new ways to treat, prevent and diagnose infectious disease." ...Despite acidity, orange juice could still be a source of foodborne disease
...re incapable of supporting the growth of foodborne pathogens or toxin production without storage time and temperature controls are defined by the U.S. Food Code as non-potentially hazardous foods. But this designation also includes foods that do not support growth but still may contain pathogenic organisms at...For diseases, when it comes to sharing a home, only close relatives will do
...urces away from a non-relative, theory assumes the pathogens will increase exploitation of the host and thus cause more severe symptoms. However, if pathogens share the host most often with close relatives, this evolutionary conflict is decreased, possibly re...Over-use of antibiotics in fish-for-food industry encourages bacterial resistance and disease
... ultimately see more and more antibiotic resistant pathogens emerging, causing increased disease to fish, animals and humans alike" said Dr Cabello. A global effort to curb the over-use of antibiotics in the rearing of finfish is essential in preventing these detrimental effects to fish, animal and human hea......al. But if the animals were exposed to certain pathogens that thrive at low temperatures, like some E. coli...e researchers suggest that an understanding of how pathogens interact with their hibernating hosts could provide valuable insight into the spread and emergence o...