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Tag: "pathogenicity" at biology news

Scientists decipher genome of fungus that can cause life-threatening infections

...chers also examined the geneticdeterminants of its pathogenicity by comparing the genomes of twoclosely related strains of significantly different virulence. "Notonly have we established a genomic platform for the further study ofthis increasingly important pathogen, but the data from the two strainsmay provide i...

Scientists identify genes responsible for 'black rot' disease in vegetables

...ers identified three genes that were implicated in pathogenicity but that were not present in the previously descri...ht the role of genome dynamics in the evolution of pathogenicity in Xcc in response to different host species. ...

Purdue researchers find key to rice blast fungus

...rdinating the fungus' attack. The enzyme, called a pathogenicity mitogen-activated protein (MAP) kinase, flips the switch that starts the cellular communication necessary to launch the fungal invasion that kills rice plants or causes loss of grain. "We found that this MAP kinase controls the penetration process, ...

Scientists determine structure of enzyme that disrupts bacterial virulence

...l step toward developing drugs that may reduce the pathogenicity of bacteria involved in biowarfare threats such as... on their quorum-sensing systems to increase their pathogenicity and resistance to antibiotics. ...

MRSA use amoeba to spread, new research shows

...s that Legionella and many pathogens learned their pathogenicity after sparring with single-celled organisms like amoeba for millions of years. Because our human cells are very similar to these primitive, single-celled organisms, they have acquired the skills to attack us". For these reasons, such primitive cell...

HIV-1's high virulence might be an accident of evolution

...disposed the simian precursor of HIV-1 for greater pathogenicity in humans." "Heightened immune activation is the only clear cut difference between pathogenic and non-pathogenic infections with the immunodeficiency viruses," Kirchhoff added. "The observed difference in Nef function may provide--for the first tim...

Resistance and genetic sensitivity to sleeping sickness

... to infection, the degree of parasite virulence or pathogenicity and the environment. An IRD team focused particularly on the role of host genetic diversity in response to T. b. gambiense infection (whether or not the disease develops). As human experimentation is excluded, genetic, epidemiological and statisti...

Antivirals effectively curb influenza virus

...he effects of each antiviral on infectiousness and pathogenicity ?the ability of the influenza virus to cause overt...rom 44 percent to 66 percent. Efficacy in reducing pathogenicity for zanamivir was 52 percent and 56 percent in the two zanamivir studies; for oseltamivir, it was 56...

Study suggests some drug resistance to influenza B medications

... influenza viruses is needed to fully assess their pathogenicity in humans.? (JAMA. 2007;297:1435-1442. Available pre-embargo to the media at www.jamamedia.org ) Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosu...

Understanding why C. difficile causes disease -- it's hungry

...w that most disease-causing bacteria express their pathogenicity when they are hungry," says Abraham Sonenshein, professor at the Sackler School of Graduate Biomedical Sciences at Tufts University and at Tufts University School of Medicine, at the 107th General Meeting of the American Society for Microbiology (ASM...

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