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Tag: "particles" at biology news

DNA Molecules Used To Assemble Nanoparticles

... delivery systems, using DNA molecules to bind the particles together. Nanometer-scaled dendrimers can be asse...ending out a signal to identify it. But making the particles is notoriously difficult and time-consuming. The nanoparticle system used by Baker's lab is based o...

Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants

...ated with zinc sulphide as fluorescent probes. The particles had adiameter of 6.3 nm. The team terminated the quantum dots withcarboxylic groups by reacting them with mercaptoacetic acid. Then theyconjugated the quantum dots with the amine groups of stigma/stylarcysteine-rich adhesin (SCA) - a plant pollen tub...

Tiny particles could solve billion-dollar problem

...red with a thin coat of palladium atoms. As metal particles get progressively smaller, a higher percentage of the atoms in the particle are found on the surface of the particle instead of being locked away inside the metal where they cannot interact with other chemicals. For example, in the bulk palladium, le...

Scientists Replicate Hepatitis C Virus in Laboratory

...hor of the study. “Our model system produced viral particles that have all the properties of the whole virus. T...microscopy showed evidence of high levels of viral particles resembling fully-formed HCV outside of the human liver cells in the culture medium. The researchers ...

Novel antiviral technology inhibits RSV infection in mice

...les -- minisculenaturally-occurring, biodegradable particles that stick tomucous-producing cells lining the lungs. The RNA produced isspecifically designed to suppress the protein NS1. Without NS1, thehost antiviral defense remains intact and the virus cannot reproduce.Mice treated intranasally with the gene-s...

Inflammatory molecules released by pollen trigger allergies

How do pollen particles provoke allergic reactions? A new study in the February 21 issue of The Journal of Experimental Medicine puts some of the blame on bioactive molecules that are released from pollen. These molecules bind to immune cells and cause them to launch a typi...

NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis

...is fails, interferons block the virus from forming particles which can be released and infect other neurons. This is critical, since the immune system does not kill infected precious neurons the way it does other cells, which can be replaced. The researchers attributed the spread of viral encephalitis to the ...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...uscle. The investigators either injected the viral particles into the muscle or injected it intravenously in Pompe disease mice. Six weeks after muscular injection with the virus containing the muscle-restricted gene, mice exhibited high levels of the enzyme and reduced glycogen content in the injected muscle...

Scientists develop new color-coded test for protein folding

...nd created a liquid solution containing nano-sized particles of gold saturated with a protein called cytochrome c. "We chose gold nanoparticles because they are simple to prepare, easy to control and cost effective," the authors wrote. "To the best of our knowledge, however, gold nanoparticles have not been p...

Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer

...referredto as “VRP-neu.?When these non-propagating particles are injected intoan animal, the vector directs the animal’s cells to make thousands ofcopies of the HER2/neu growth protein, says Lachman.In addition, the VRP-neu preferentially homes to specialized immunesystem cells known as dendritic cells, and in...

Highly adaptable genome in gut bacterium key to intestinal health

... we found that the microbes attached to small food particles in the intestine," Gordon says. "These carbohydrate-rich particles are the bacteria's dining room tables. By generating a series of carbohydrate-binding proteins on it...

A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020

...referredto as “VRP-neu.?When these non-propagating particles are injected intoan animal, the vector directs the animal’s cells to make thousands ofcopies of the HER2/neu growth protein, says Lachman.In addition, the VRP-neu preferentially homes to specialized immunesystem cells known as dendritic cells, and in...

Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells

...s problem will be solved by winnowing out unlikely particles through size and frequency. ...

Breakthrough method in nanoparticle synthesis paves the way for new pharmaceutical and biomedical applications

...-synthesis technique that produces nanometer-sized particles of between 50 and 300 nm with tunable pore sizes i...ttempts at synthesizing such nanoparticles created particles that were limited in the type of structure, degree of structural ordering and range of pore sizes. M...

Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin

Nano-sized particles embedded with bright, light-emitting molecules have enabled researchers to visualize a tumor more than one centimeter below the skin surface using only infrared light. A team of chemists, bioengineers and medical researchers based at the University o...

NYU study reveals how brain's immune system fights viral encephalitis

...is fails, interferons block the virus from forming particles which can be released and infect other neurons. This is critical, since the immune system does not kill infected precious neurons the way it does other cells, which can be replaced. The researchers attributed the spread of viral encephalitis to the ...

Nanoscale Diagnostic Sets Sights on Alzheimer's

...e biomarker targets ?in this study, the ADDLs. The particles are magnetic, a property that aids collection at t...t at the end of the test. Ultimately, the gold-DNA particles and magnetic particles sandwich the biomarker targets. A magnet separates the sandwich complexes fr...

Nanoparticles offer new hope for detection and treatment

...cerous growth. "One of the best advantages of the particles is that we designed them to detect tumors using th...tes a high density of contrast agent, and when the particles bind to a specific area, that site glows brightly in MRI scans. In this study, MRI scans picked up ...

Nanoparticle Breast Cancer Drug Approved by FDA

...ion approval of Abraxane (paclitaxel protein-bound particles for injectable suspension), indicated for the trea...tein-bound nanoparticle technology) to create tiny particles (nanoparticles 100th the size of a red blood cell) in which the active chemotherapeutic drug, paclit...

Shutting down the HIV assembly line

...hinery to produce carbon copies of itself. New HIV particles roll off the cellular assembly lines, burst like b...types, Gag and the HIV viral envelope protein form particles in the multivesicular body; in other cell types, Gag makes its way from this site to the cell membra...

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