Columbia University licenses next-generation DNA sequencing technology
...National Academy of Sciences (PNAS). This research paper describes the details of the Sequencing by Synthesis Chemistry and how the approach overcomes accuracy limitations of other next generation DNA sequencing systems. It was also recently announced that Columbia University in collaboration with the Wal...Mutant mouse provides insights into breast cancer
... material, leading to mouse breast cancers. In a paper published in Nature Genetics online (and upcoming in the Dec. 27 print issue), the Cornell geneticists report that by extensively testing hundreds of mice pedigrees, they found a mutant line of mice called Chaos3 that had a 20-fold increase in a hall...Scientists find new way to manipulate DNA
... scission, said Solomon, who is the co-author on a paper published last week in the Proceedings of the Nati... cause polymers to break in turbulence. "This paper understands how they are breaking in a new way that resolves some issues that have been present for ...Researchers make nanosheets that mimic protein formation
...s and post doctoral researchers have co-authored a paper scheduled to appear Oct. 13 in the journal Science. "The importance of this work is in making a key connection between the world of proteins and the world of nanotechnology" Kotov said. "Once we know how to manipulate the forces between the nanopar...Biologists probe the machinery of cellular protein factories
...s of the ribosome move during protein synthesis. A paper describing the new findings will be published in the September 22 issue of the journal Cell and is currently available online. "We can now explain a lot of the results from biochemical and genetic studies carried out over the past several decades,...Scientists find mutations that let bird flu adapt to humans
...Yoshihiro Kawaoka, the senior author of the Nature paper and a virologist at the University of Wisconsin-Madison School of Veterinary Medicine. "Both changes are needed for the H5N1 virus to recognize human receptors." The new report provides a molecular blueprint for the genetic changes required to tra...Engineer ramps up protein production, develops versatile viral spheres
...ioengineering, and recognizes the most outstanding paper of the year in that journal. Swartz, who holds the...ineering at Stanford, will receive the award for a paper showing for the first time how glucose, the abundant sugar produced by photosynthesis and used in ma...Down syndrome: It's not just the age factor
..., is expected to relax. Neuhäuser and Krackow's paper provides evidence that older mothers, who give birth to children with Down Syndrome, have a relaxed stringency of quality control of embryos (or relaxed filtering stringency), which increases the probability that these women will bring children with ...What's next for gene therapy? Plastic
...sion, Yong Woo Lee at VT-WF SBES, and Long. "The paper defines a new paradigm for research," said Long. Layman, whose bachelor of science degree is from Virginia Commonwealth University in chemical engineering, "typifies the way we are going to educate students in the future," Long said. "He is an engine...U of S Vaccine and Infectious Disease Organization team discovers key step in flu virus replication
...d pave the way for new drugs and vaccines. The paper will appear in the January 2007 issue of the Journal of General Virology and recently has been given advance on-line publication. "The work we are doing will be applicable to all influenza viruses, including influenza A virus subtype H5N1," said ...New dyslexia theory blames 'noise'
...attention in a broad sense.... "This is a great paper of very high significance... As people like Steve Grossberg [of Boston University] have argued for many years, attention ... is crucial for stable learning of categories." Ziegler called for preventive training for children with weak speech perce...Quantum dots reviewed -- Could these nanoparticles hold the cure to cancer?
...alysis plus Quantum Dot drug delivery systems. The paper also outlines some early success in the detection and treatment of breast cancer. The paper concludes with a quick look at what the future may hold for Quantum Dots in providing new insights ...Exposure to dioxins influences male reproductive system, study of Vietnam veterans concludes
...ducts of processes such as incineration, smelting, paper and pulp manufacturing and pesticide and herbicide production. Humans are exposed to these chemicals primarily through consumption of animal fat and dairy products. Babies are exposed to the highest levels of dioxins through breast milk. Dioxins a...Two central mysteries in genome inheritance solved at UCSD
...he cancer with fewer side effects." The second paper from Desai's research group, to be published in the December 15 issue of Cell, identifies a different type of connection between chromosomes and microtubule polymers, which operates to discriminate between correct and incorrect chromosome-spindle att...Beyond the book: Software automates access to brain atlases
...ical methods" from Swanson's lab, according to the paper on the project Burns co-authored, published this month in the online journal BMC Bioinformatics. The NeuARt approach draws from a wide range of methods of displaying and organize visual information. The challenge is making it easier to consu...Stanford discovery may help predict when toxoplasma can be deadly
...ighlighted in the same issue of Science by another paper with similar findings from a different group of r...f the proteins' critical role will be offered by a paper slated to appear in an upcoming issue of Nature, in which Boothroyd and his colleagues describe th...Flu shot effective against drifted influenza, nasal spray vaccine less so
...to people between age 5 and 49 years. In another paper in the same edition of the New England Journal of Medicine, FluMist was administered to school children and the children were followed to see if they and their families had been protected against flu. The study's authors conclude that vaccinating chi...UCSD researchers create roadmap to integrin activation
...of Hematology/Oncology, and colleagues published a paper in the journal Science about the discovery that talin ? a large cytoplasmic protein that binds to the inside of an integrin or family of integrins ?delivers the critical activation signal. Talin is very important in the linkage between a cell's cyt...Cellular traffic backups implicated in skeletal malformations
...of Nature Genetics ?and back-to-back with Knapik's paper ?a group of researchers from the University of California at Davis report the human variant of this gene, which causes a craniofacial condition called CLSD (Cranio-Lenticulo-Sutural Dysplasia) with strikingly similar defects to the crusher fish. Al...... death 1 (PD1), for example, suggested by the PNAS paper as playing a role in post-trauma organ failure, is...e T cell shutdown. The research for the current paper was conducted under the auspices of a Large-Scale Collaborative Award from the National Institute of...