Common cancer gene sends death order to tiny killer
...croRNAs stick to messenger RNAs and, like crumpled paper jammed in a copy machine, prevent proteins from being made. Josh Mendell, M.D., Ph.D., an assistant professor in the McKusick-Nathans Institute of Genetic Medicine, suspected that p53 activates microRNAs like miR-34a because a number of studies h...Cellular message movement captured on video
...le,” said Shu Chien, the senior author of the BBRC paper and a professor of bioengineering at UCSD’s Jacobs School of Engineering. “But it’s really very complex and I’m not sure we’re covering much as yet. We certainly don’t know all the interactions among these molecules that bring the cell into action.” ......recognize, much less understand,” Gould says. “Our paper highlights the importance of studying their basic biochemistry and cell biology, which can yield a better understanding of normal human biology as well as identify new avenues in the fight against human disease.” ...Pesticides choke pathway for nature to produce nitrogen for crops
...er yields or significantly delayed growth. In a paper appearing online this week ahead of the regular pu...g pentachlorophenol (PCP), in in-vitro assays. The paper in PNAS reports their in-vivo findings using real plants and bacteria. None of the chemicals used...Brightening prospects of using fluorescent nanotubes in medical applications
...plications, including anti-cancer treatments. In a paper published online in the Journal of the American Chemical Society on June 7, they describe a method that can successfully produce large batches of highly fluorescent nanotubes. “Nanotubes have a number of characteristics that make them particularly...Breakthrough developments in rheumatoid arthritis reported
... risk for rheumatoid arthritis by 30 percent. (The paper reporting the gene is in press.) In collaborations with other scientists worldwide, Dr. Gregersen has also been able to show that certain markers are strongly linked to certain ethnic groups and others are not. “This will help us in figuring out...Now, self-healing materials can mimic human skin, healing again and again
...and engineering, and the corresponding author of a paper accepted for publication in the journal Nature Materials, and posted on its Web site. “The vascular nature of this new supply system means minor damage to the same location can be healed repeatedly,” said Sottos, who also is a researcher at the un...Undergraduate research shows leaderless honeybee organizing
...r, Pierce’s mentor. Pierce was first author on the paper – a rare achievement for an undergraduate. “It ...rce and Schneider have documented in their current paper how workers use the vibration signal to prepare the queen for swarming by making intrusions into her...Physicist cracks women's random but always lucky choice of X chromosome
...e together within the cell. The Warwick researcher paper says that what happens next is that material for a "protein plug" then begins to gather around both of the XIST suicide genes on each X Chromosome. This starts a race between the two build ups of protein. Inevitably one of these two nascent protein p...Study shows lizard moms dress their children for success
...he conditions they will encounter as adults. In a paper published June 10 in the online early edition of the journal Ecology Letters (and in a later print issue), the researchers reported that female side-blotched lizards give an extra dose of the hormone estradiol to their eggs in certain social circumst...Microbes at work cleaning up the environment
...” said Peter Weber, one of the LLNL authors of the paper appearing in the June 15 edition of the journal Science. Weber and LLNL colleague Ian Hutcheon used LLNL’s NanoSIMS (high- resolution secondary ion mass spectrometer) to study the metal-sulfide nanoparticle aggregation in sulfate-reducing bacteria...New findings challenge established views on human genome
...lapping ways not yet fully understood. In a group paper published in the June 14 issue of Nature and in 28 companion papers published in the June issue of Genome Research, the ENCyclopedia Of DNA Elements (ENCODE) consortium, which is organized by the National Human Genome Research Institute (NHGRI), part...Bacteria ferry nanoparticles into cells for early diagnosis, treatment
... cells," said Akin, the first author of a research paper appearing online this week in the journal Nature Nanotechnology. Experiments were carried out in cultures of human cancer cells, including intestinal, oral, liver, ovarian and breast cancer cells. The researchers also tested their method on live m...Herpes virus hijacks DNA repair process
...velop novel strategies to treat infection." The paper appears online this week in Cell Host & Microbe. Scientists have known for some time that viral infection of cells activates the DNA damage response. But researchers had assumed that this activation occurred because repair mechanisms were mistak...Marine phytoplankton changes form to protect itself from different predators
...a lot smarter than scientists had suspected. In a paper published June 11 in the online version of Proceed...others contend its food role is small. While this paper won’t resolve the dispute, Hay believes it shows that both points of view could be correct – dependi...Runners -- Let thirst be your guide
...etion. Verbalis noted in his Sports Medicine paper that since 1985, “well over 100 individual cases” of EAH have been reported from physical exercise activities as diverse as forced military marches, prolonged hiking and marathon, ultramarathon and triathlon races, and there have been at least 8 docu...UCF nanoparticle offers promise for treating glaucoma
...c application for glaucoma. In their paper on the research, which was also supported by the National Science Foundation, Seal and Mallik note the results are “very promising” and that their nanoparticle configuration offers seemingly limitless possibilities as a non-toxic drug delivery tool....Endosome-mediated signaling in plants
In a paper that will be published online in advance of its July 1st publication date, Drs. Niko Geldner, Joanne Chory and colleagues (The Salk Institute and HHMI) demonstrate that endosomes can function as signaling platforms in plants, as well as in animals. ...Revealed -- Mosquito genes that could be controlling the spread of killer viruses
...f Cell and Molecular Biology, senior author on the paper explains: “Our study has revealed the genetic ‘landscape’ made by parts of this mosquito’s newly-sequenced genome which are involved with immunity. By working to understand as much as possible about these genes, and the way they interact with specifi......in Gurney of Purdue University, a co-author of the paper and coordinator of the TransCom study. "To figure out exactly what is happening, we need improved models and more atmospheric observations."...