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Tag: "pancreatic" at biology news

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

... nutrients from the mother to the baby, the baby's pancreatic cells will be programmed abnormally," said princip...found no difference in pancreas size or numbers of pancreatic beta cells, which produce insulin. But cultures of the beta cells revealed the answer: the undernou...

UCSD researchers maintain stem cells without contaminated animal feeder layers

...ulate cellular growth and differentiation in human pancreatic cells. Human embryonic stem cells cultured for several weeks under these conditions showed no change in cell form and structure. The team then eliminated each factor and pluripotency was assessed. At first, the results were narrowed to three molecule...

Newly Discovered Compound Blocks Known Cancer-Causing Protein

...ound in half of all colon cancer and 90 percent of pancreatic cancers, among other cancers. Casey and his colleagues in Duke's Department of Pharmacology and Cancer Biology have already discovered and developed another class of cancer drugs aimed at inhibiting the processing pathway --the prenylation pathway ?...

Agilent Technologies releases automated literature search tool for biology researchers

... Research Institute (TGen) on melanoma, autism and pancreatic cancer. Labs researchers are focusing on proteomics and metabolomics for these diseases as a complement to Labs collaborators' work in genomics. Using Labs' systems biology informatics prototypes, Labs researchers have built qualitative biological mo...

New drug shows promise as powerful anticancer agent

...iety of human tumors, including liver, breast, and pancreatic cancers that were grown in mice. ON01910 was also highly effective and, in many cases, strongly synergistic when tested in combination with other chemotherapeutic agents. Studies examining normal human cells show that, in contrast to tumor cells, the...

Rare surgery performed to remove pancreas, prevent diabetes

...is entire pancreas and the hours-long wait for the pancreatic islet cells to be processed in a specialized UAB l...ted facilities necessary to isolate and purify the pancreatic islet cells either from a cadaver donor for transplantation or, as in this case, for infusion back i...

Genetic defects give the immune system the green light to attack the pancreas

...e in the United States have type 1 diabetes. Their pancreatic beta cells can no longer make insulin. Without this crucial hormone, their body cannot convert food into energy. To sustain life, they must get insulin through injections. The disorder can emerge in childhood, adolescence and even appear in adulthood...

Biomarkers isolated from saliva successfully predict oral and breast cancer

...er difficult to detect cancers such as ovarian and pancreatic cancers. "In my mind the biggest hurdle stems from the fact that salivary nucleic acids or protein markers might be influenced by eating, drinking, smoking, diet or oral hygiene," said Wong. "So our goal is to provide the optimized and standardized ...

Disease progression model of pancreatic cancer developed by Penn researchers

...hool of Medicine have developed an animal model of pancreatic cancer that closely mimics disease progression in ...p new treatments for this deadly disease. Advanced pancreatic cancer is among the most lethal of cancers, with a one-year survival rate after chemotherapy of only...

Newly Discovered 'Branding' Process Helps Immune System Cells Pick Their Fights

...h. He notes that insulin-producing beta cells, the pancreatic cells attacked by T cells in type 1 diabetes, also generate reactive compounds similar to those made by antigen-presenting cells. "The beta cells could therefore be modifying their own proteins in the same way that antigen-presenting cells are modif...

Precise Timing Enabled Pig-to-rat Transplants To Cure Diabetes

...n and Rogers had shown that transplantation of pig pancreatic primordia into diabetic rats cures their diabetes ...appears to be relatively little difference between pancreatic primordia from 28-day-old and 35-day-old pig embryos. "To put this in perspective, pig gestation is ...

Second messenger NAADP shows fast, dose-related impact on satiety cycle

...le in cholecystokinin-induced Ca2+ mobilization in pancreatic acinar cells. Despite the intensive study into the physiological role of NAADP in Ca2+ signaling in pancreatic anicar cells, direct demonstration of changes in NAADP levels in response to agonist-stimulations ha...

Searching the depths of the straits of Florida for disease cures

... chemicals currently showing potential in fighting pancreatic cancer. The upcoming expedition is being supported through funds appropriated by the Florida legislature and approved by Governor Jeb Bush as part of the state's response to the U.S. Commission on Ocean Policy's (USCOP) historic 2004 report. The rep...

High-powered gene profiles provide clues to genes involved in common form of lung cancer

...ompared their data for NSCLC with similar data for pancreatic cancer, and found that both diseases have some chromosomal irregularities in common, suggesting that in both disorders, some of the same genes may be driving the tumors. ...

Study: Well-known protein helps stem cells become secretory cells

... say. In juvenile (type I) diabetes, for example, pancreatic cells that normally produce and secrete insulin do...lem, the researchers note. "The key is knowing how pancreatic cells know what hormones to produce and release, or how any gland does, and the new findings add to ...

New imaging technology shown to detect pancreatic inflammation in type 1 diabetes

... reveal the otherwise undetectable inflammation of pancreatic islets in recently diagnosed diabetic mice. As T l...ood vessels of the body including the pancreas. If pancreatic vessels have become leaky from inflammation, the magnetic particles spill into nearby tissues, where...

Naturally occurring asbestos linked to lung cancer

... group, an equal number of age- and gender-matched pancreatic cancer cases was selected (since pancreatic cancer has no known association to asbestos exposure). For both the mesothelioma and pancreatic canc...

Researchers make 'embryonic-like' stem cells from umbilical cord blood

...ation. "We plan to use this technology to engineer pancreatic tissue as we work towards our goal of developing a cure for type 1 diabetes," he added. The team's report will be published in the Cell Proliferation Journal on 18 August. ...

Insight into the processes of 'positive' and 'negative' learners

...ation. "We plan to use this technology to engineer pancreatic tissue as we work towards our goal of developing a cure for type 1 diabetes," he added. The team's report will be published in the Cell Proliferation Journal on 18 August. ...

Researchers propose measures to curb lion attacks in Tanzania

...ation. "We plan to use this technology to engineer pancreatic tissue as we work towards our goal of developing a cure for type 1 diabetes," he added. The team's report will be published in the Cell Proliferation Journal on 18 August. ...

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