The power of one: A simpler, cheaper method for cell fusion
...C voltage and would enable researchers to fuse one pair of cells at a time." Electrofusion - the proces... in an aqueous chamber within the chip, where they pair off. In contact with one another but not yet fused, the cells flow towards the only exit, which is a...New technology to speed up research into Huntington's disease
... it. When the mice were then presented with a new pair of stimuli, this proved too difficult even for the younger HD mice. Importantly, and where the screen is so valuable, all the HD mice were physically able to complete the task (i.e. they were able physically to touch the screen and obtain rewards,...Artificial cornea offers better results for infants, some blind patients
...transplants on thousands of patients. Together the pair has logged more than 100 years treating patients blinded by severe cornea disease or injury and creating new ways to treat them. Among the efforts has been a series of designs for artificial corneas, which in adults are primarily for patients whos...Nanoparticle assembly enters the fast lane
...s advantage of this molecule's natural tendency to pair up components called bases, known by the code letters A, T, G and C. "In biology, DNA is mainly an informational material, while in nanoscience, DNA is an excellent structural material due to its natural ability to self-assemble according to well...Geneticists discover genes that make fruit fly hybrids sterile
...esearchers have made the first identification of a pair of genes in any species that are responsible for problems unique to hybrids. Specifically, the researchers have found two genes from two fruit fly species ( Drosophila melanogaster and D. simulans ) that interfere with each other, thereby preventin...For crickets, parasitic flies can stop the music
...e flies themselves. The findings, reported in a pair of recent papers in the journals Ethology and Animal Behavior, are of interest because they shed light on the interplay between the powerful evolutionary forces of sexual selection and natural selection, said UF zoology professor Jane Brockmann. O...Single molecular 'mark' seen as pivotal for genome compaction in spores and sperm
...the companion strand as a reference. Bases in DNA pair only in predetermined combinations, so that one strand can serve as a template for the other. "Compaction might also affect sperm fertility and function in the higher organisms, and thus the propagation of the species," says Thanuja Krishnamoorthy, ...Two central mysteries in genome inheritance solved at UCSD
...new cell has a complete set of chromosomes. In a pair of papers in the journal Cell ?one published in th...ts. Each replicated chromosome is comprised of a pair of identical sister chromatids, generated by the copying of the parental DNA strand. These pairs ar...Male chimpanzees prefer mating with old females
...uggests that species that appear to lack long-term pair bonding and menopause (such as chimpanzees) should... in addition to supporting the idea that long-term pair bonding and menopause may contribute to the preference of human males for young females, also sugges...Perceived facial similarity in children is an estimate of kin recognition
...e only asked to rate the facial similarity of each pair of children. In a second condition, participants were asked to classify each pair as sibling or non-siblings. Researchers found that the mean similarity ratings of the first group c...Wolves are suffering less from inbreeding than expected
...ants from the larger Russian-Finnish population; a pair around 1980 and a single male ten years later. With so few individuals founding the population the level of inbreeding is high. By the use of DNA-analyses the research team has previously reconstructed a pedigree of the whole population. This kind of...Scientists solve 30-year-old mystery of mutant mouse's kidney woes
...ne from other normal mice, and found a single base pair had changed." The change swaps the amino acid serine for the amino acid leucine at a key position in the protein. Serine can undergo phosphorylation, a form of chemical modification frequently used in biological processes; leucine cannot. This chan...Scientists use gene signatures to match cancer and other diseases with potentially effective drugs
... The method also enabled researchers to match up a pair of natural products, known as celastrol and gedunin, with a mechanism by which some advanced prostate tumors continue to grow aggressively despite hormone-blocking treatments. A paper in Cancer Cell reports on this work, which made it possible for sc...Study defines effective microbicide design for HIV/AIDS prevention
..." he said. "Our findings demonstrate the need to pair potent active ingredients with well-engineered delivery vehicles, and they highlight the importance of the dosage form -- especially its ability to restrict viral diffusion and remain in place -- in microbicide effectiveness," Katz added. More than...What controls stickiness of 'smart' chromosomal glue
...d cohesins, which hold the members of a chromosome pair together until just the right moment during cell d...c recombination, after each member of a chromosome pair has replicated to produce identical sister chromotids in the initial stage of meiosis, the chromosom...Methane-belching bugs inspire a new theory of the origin of life on Earth
...n of life on Earth, reconciling a long-contentious pair of prevailing theories. This new, "thermodynamic"...n a biochemical pathway that includes a well-known pair of enzymes, called Pta ("phosphotransacetylase") and Ack ("acetate kinase"). The two researchers rea...Carnegie Mellon researchers discover key deficiencies in brains of people with autism
In a pair of groundbreaking studies, brain scientists at Car... number eight when rotated 90 degrees looks like a pair of eyeglasses") or low imagery content ("Addition, subtraction and multiplication are all math skill...'Pinball protons' created by ultraviolet rays and other causes can lead to DNA damage
...l of a proton from the Guanine-Cytosine (G-C) base pair is involved in creating lesions that can lead to replication errors. This pair has 10 protons, meaning there are numerous targets for processes that knock the protons off. The le...When it comes to gene transcription, random pauses aren’t quite so random, study finds
...xperimental DNA templates using a special 240-base pair sequence that triggers one of two types of long pa...lly cool DNA templates that have the same 240-base pair sequence repeated over and over again eight times in a row," Block said. When molecules of RNAP were...Bedsores and bald hides: Novel roles revealed for a 'scaffolding' protein
...g apart turns out to have much wider utility. In a pair of reports, the protein K17 has been found to also influence wound healing and maintain the structural integrity of hair follicles, according to Johns Hopkins researchers. The wound-healing work, published in the May 18 issue of Nature, sheds light ...