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Tag: "pain" at biology news

New understanding of COX-1 and COX-2 enzymes could revise classification of pain meds

COX-1 and COX-2 enzymes may be blocked by pain medications such as Advil and Vioxx in a more comp...e classify the commonly used anti-inflammatory and pain drugs for aches, pains, and fever," says Colin Funk, a professor of Biochemistry and Physiology at Q...

Epidemic of unneeded amputations

...e's leg with CLiRpath. Today, Sevante is virtually pain free. "After my first amputation, I would have done anything to avoid a second," said Sevante. "Had I not asked for an alternative, I fear I was on track for the loss of another limb. This would have meant the beginning of the end for me." ...

New McGill research shows mice capable of empathy

...liar to each other) and able to see one another in pain were more sensitive to pain than those tested alone. The results, which for the first time show a form of "emotional contagion" ...

Trial success for diabetic nerve therapy

...f neuropathy that can cause numbness and sometimes pain and weakness in the hands, arms, feet and legs. Progression to amputation is not inevitable, but it is always a threat. Problems may also occur in other organs, including the heart, kidneys, sex organs, eyes and digestive tract. "Diabetic neuropat...

COX-2 inhibitors significantly reduce risk of cancer

...tudy show that regular use of popular prescription pain relievers may reduce the risk of breast cancer by ...," says Harris. Celebrex is still widely used for pain relief, but Vioxx was pulled off the market in 2004 following reports of heightened risk of heart at...

Stem cells can repair torn tendons or ligaments

... leading to the very common phenomenon of low-back pain affecting a major part of the population. Until the present time, therapeutic options used to repair torn ligaments and tendons have consisted of tissue grafting and synthetic prostheses, but as yet, none of these alternatives has provided a succes...

Obese people are more sensitive to pain, suggests study

Obese people may be more sensitive to pain than people who aren't obese, a new study suggests...ee, a disease that causes inflammation and extreme pain in the knees. Participants were given a mild electrical stimulation on their left ankle to measure ...

All placebos not created alike

...l." The study of 270 individuals with chronic arm pain had two phases. In the first phase, 135 patients ...ial, and the other half in a placebo pill vs. real pain pill trial. The acupuncture trial extended four more weeks (the length believed needed to see impro...

New licensing agreement to maximize AIDS drug development

...United Kingdom by ProStrakan, for the treatment of pain associated with chronic anal fissures. A similar formulation of Rectogesic is currently being sold in Australia, New Zealand, Singapore and South Korea. FortigelTM (testosterone gel), branded Tostrex® outside the United States, is marketed in Swede...

Novel method reveals how menthol discovery could point towards new or improved pain therapies

... understanding could lead to potential advances in pain therapy, the researchers said. Moreover, the scie...ature-activated ion channels can result in chronic pain syndromes," said Ardem Patapoutian, associate professor at Scripps Research and member of GNF, who d...

Therapeutic prospects beyond Vioxx

...isk using the same mechanism by which they relieve pain and inflammation". The investigators also addres...as effective as treatment with NSAIDs in models of pain and inflammation. This has prompted several large pharmaceutical companies to develop drugs targetin...

Brain differences could explain why males and females experience pain relief differently

...n may explain sex differences in the experience of pain and in the effects of certain drugs on pain. Th...s of the brain responsible for the transmission of pain sensations in the body. The study used rat brains, but a host of clinical evidence suggests that si...

Study in Science holds promise for a new approach to drug therapy

...can provide better control of pathways involved in pain relief, inflammation and heart disease, while leav...me in on the site of infection. The other involves pain relief brought about by morphine. In white blood cells, the free G protein gamma-beta subunit acti...

Great (taste) expectations: Study shows brain anticipates taste, shifts gears

...alves taken by unwitting subjects are seen to ease pain or have some other beneficial physiological effect. How the brain processes this faked input and prompts the body to respond is largely a mystery of neuroscience. Now, however, scientists have begun to peel back some of the neurological secrets of t...

Master genetic switch found for chronic pain

... the animals' response to "neuropathic pain." Such pain is abnormal pain that outlasts the injury and is associated with nerve and/or central nervous system changes. The ani...

Pain killer fights breast cancer by targeting key enzyme

...ti-inflammatory drug (NSAID), a drug that controls pain and inflammation. Studies of other NSAIDs, such as ibuprofen, have suggested that NSAIDs may reduce breast cancer incidence by 40 percent. However, these drugs tend to halt aromatase production throughout the body. Brueggemeier presented the work w...

Simple idea to dramatically improve dengue vaccinations

... disease," Dengue is characterized by excruciating pain and was "the most important mosquito-borne viral disease affecting humans" in 2005 according to the U.S. Centers for Disease Control. The study, from bioengineers and physicists at Rice University, appears in the March 24 issue of the journal Vaccin...

Technique makes it easier to see mouse embryo in all its glory

...ptions that our toothpaste, artificial sweeteners, pain relievers and household cleaning chemicals are safe for pregnant mothers," he said. "The EPA (U.S. Environmental Protection Agency) and FDA (U.S. Food and Drug Administration) mandate that chemical and drug companies perform tests of reproductive saf...

Rare Tibetan antelope listed as endangered

...ethods have the advantage of reduced postoperative pain and a faster recovery. However, the two-dimensional ultrasound imaging now available offers surgeons only a limited view, which can impede their depth perception and make such procedures difficult to master. "Our ultrasound device could really advan...

3D ultrasound device poised to advance minimally invasive surgery

...ethods have the advantage of reduced postoperative pain and a faster recovery. However, the two-dimensional ultrasound imaging now available offers surgeons only a limited view, which can impede their depth perception and make such procedures difficult to master. "Our ultrasound device could really advan...

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