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Tag: "pain" at biology news

Susceptibility to Crohn's disease -- an important new clue

...developed world. Common symptoms include abdominal pain and diarrhea, but the disorder is often associated with debilitating clinical complications. Researchers from the University of Liège, Belgium, have now uncovered an important clue to the susceptibility of individuals to this disease. In a genome-wi...

Long-term narcotics use for back pain may be ineffective and lead to abuse

...24 percent of cases. "Patients with chronic back pain commonly request pain medication, and opioid medications are used despite the concerns clinicians have with patients devel...

FDA causes unnecessary scare about common painkillers

...n (FDA) has caused an unnecessary scare about some pain relievers by adding a warning to drugs that are sa...s the agency has failed to recognize the harm of a pain reliever that should be taken off the market. "The FDA is adding 'black box' warnings to all prescr...

Scripps Research study reveals new activation mechanism for pain sensing channel

...rs found that TRPA1, a protein that helps transmit pain signals, is a direct sensor of reactive chemicals.... and pungent compounds were known to activate this pain receptor, we discovered that they do so by directly and irreversibly binding to the cysteine amino a...

Common parasitic infection leads to increased risk for HIV infection

...ll as itching of the genital area. Lower abdominal pain occurs in rare cases. The study, conducted by R. Scott McClelland, MD, MPH, and colleagues at the University of Washington in Seattle, the University of Nairobi, and the Coast Provincial General Hospital in Kenya, followed 1,335 HIV-seronegative ...

Chronic pain up almost 40 percent among US workers in past decade

Persistent, chronic pain has risen dramatically among full-time U.S. worker...red by Ortho-McNeil Pharmaceutical, Inc. "Chronic pain appears to be increasing in prevalence among U.S. workers as Americans age and lead more sedentary l...

ASU researchers test antibacterial effects of healing clays

...e toxin is immunosuppressant; the patients feel no pain and the body mounts no response to infection. It leads to disfigurement, isolation, not unlike that seen in leprosy," Haydel explains. "Traditional antibiotics can only make a difference at the very earliest stages of the disease, so treatments have,...

Trying to control pain can be a double-edged sword, say scientists

... has implications for how patients with persistent pain can cope with what is often a debilitating conditi...tly, the team went on to show that when faced with pain beyond their control, people who tend to feel more in control of their own lives show a lower respon...

Backache beaten by good vibrations?

...cruiting people with backache caused by nerve root pain ?commonly known as sciatica ?in the first ever stu...e volunteers will receive advice on managing their pain and either eight sessions of therapeutic ultrasound (TU) or eight sessions of sham TU. They will als...

New brain-chemistry differences found in depressed women

...stem that is a central part of the brain's natural pain and stress-reduction system. The findings also sho...s previously used to see how the brain responds to pain ?and to placebo pain treatment. The technique uses a form of a drug called carfentanil, which bi...

Tarantula venom and chili peppers target same pain sensor

...om a West Indian tarantula has been shown to cause pain by exciting the same nerve cells in mice that sens...olecular strategy to deter predators -- triggering pain by activating a specific receptor on sensory nerves. The research provides new tools to understand h...

Origin of inherited pain disorder pinpointed

...rare inherited disorder that causes severe burning pain with no warning has been pinpointed by researchers. They found that paroxysmal extreme pain disorder (PEPD) is caused by specific mutations in porelike sodium channels in peripheral nerve cell...

Progress made in HIV vaccine development

...ut higher doses led to some adverse events such as pain and fever. By week 4 following immunization, 93.3% of vaccinees experienced positive CD4 T cell responses, and 60% experienced positive CD8 T cell responses. "HIV-specific CD8 cell responses clear virus infected cells, and appear during the declin...

Neural networking nanotubes

...leagues report that such devices might find use in pain management, for instance, where nerve cells involved in the pain response might be controlled by reducing the activity of those cells. An analogous device might be u...

Fast test for low blood flow in dogs detects early heart trouble

...ood vessels begin to narrow long before mild chest pain and other symptoms occur, leading to reduced blood flow that gradually starves the heart of needed oxygen and nutrients. According to Lardo, blood flow in these tiny vessels can be readily detected by high-resolution equipment like 64-CT scanners...

New sunscreen ingredient to heal sunburn and help prevent skin cancer

...he skin burns. This reduces the inflammation and pain that goes with sunburn ?which is exacerbated by the iron - and also prevents the build up of harmful sunlight-generated free radicals, which can lead to the development of skin cancers. The new ingredient is light-responsive and only becomes active...

Drug can quickly mobilize an army of cells to repair injury

...r from poor circulation in their limbs that causes pain or sores and may lead to amputation. The potentia...ng improvement in blood flow, heal ulcers, relieve pain and prevent amputations." ...

A new target for painkillers

A brand new approach to treating severe nerve pain ?by aiming drugs at a previously unrecognized mole...ew way to treat a chronic and debilitating form of pain suffered by hundreds of millions of people on Earth," says J. Michael McIntosh, a University of Utah...

Two central mysteries in genome inheritance solved at UCSD

...lls, resulting in adverse side effects, like nerve pain and loss of sensation ," said Desai. "If we could specifically target dividing cells, we should improve on current chemotherapy to treat the cancer with fewer side effects." The second paper from Desai's research group, to be published in the De...

New mechanism underlying pain found

...or the development of new ways to treat the severe pain associated with such common conditions or diseases...oscience. Neuropathic pain, or the spontaneous pain and abnormal sensitivity following a nerve injury, typically results from a traumatic injury, an inf...

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