Hopkins researchers discover genetic switch that turns off an oxygen-poor cell's combustion engine
...gene HIF-1 as it helps cell survive when a lack of oxygen decreases production of an energy-rich molecule ca...is an organelle that breaks down the glucose-using oxygen and produces ATP. The other does the same thing - albeit less efficiently - without using oxygen in...Free-radical busting antioxidants might not promote healthy hearts
...col has nothing to do with its ability to scavenge oxygen free radicals, as the free radical-busting part of the drug alone was ineffective in protecting animals against heart disease. Instead, a different part of the probucol molecule was doing the beneficial work. In fact, contrary to widely accepted opi...Don't hold your breath: Carp can manage without oxygen for months
...understanding how some animals cope with a lack of oxygen might give clues as to how to solve this problem i... addition its blood has a much higher affinity for oxygen than any other vertebrate, and it makes tranquilizers and produces alcohol when oxygen supplies are ...Brain's own cannabis compound protects against inflammation
...n they damaged the brain tissue by depriving it of oxygen and glucose. The researchers also found that when they used a drug to block the receptors on microglial cells by which AEA effects the cells, inflammatory damage was increased. The researchers also explored the mechanism by which AEA prevents infla......wn in small containers, the limiting factor is the oxygen that can reach the roots; thereby, a substrate much more porous than earth is needed. Normal soil encloses some 50% of air in its interior, while this substrate encloses 90% of air and 10% of solid material. This is why these substrates accelerate th...Possible brain hormone may unlock mystery of hibernation
...serves and withstanding extreme cardiovascular and oxygen stresses--the candidate hormone might also pave the way toward clinical therapies that lend humans the same kind of protection, they added. The researchers earlier found that concentrations of "hibernation-specific protein" complex (HPc) decline in ...Plants used to detect gas leaks, from outer space!
...imes that of CO2. When plant roots are starved of oxygen the stress caused to the plant can be quantified f...ng methane means the plant roots cannot get enough oxygen and so aerial parts of the plant appear stressed in satellite images detecting reflected light. Th...Proteins stop blood-vessel and tumor growth in mice
...sel formation in mice." Tumors need nutrients and oxygen supplied by blood vessels in order to grow. They also use blood vessels to spread to other parts of the body. This process, known as metastasis, is the most lethal stage of cancer and the leading cause of cancer-related death. Fighting cancer by star...Inside rocks, implications for finding life on Mars
... the composition of the fossils changed; nitrogen, oxygen and sulfur were removed, leaving carbon and hydrogen. Confocal microscopy uses a focused laser beam to make the organic walls of the fossils fluoresce, allowing them to be viewed in three dimensions. The technique, first used by biologists to study ...Weighting cancer drugs to make them hit tumors harder
...us mechanisms by which a tumor's blood vessels and oxygen levels influence its growth and its demise. "Artificially increasing the weight of a drug gives us a means to increase the amount of drug going to the tumor while reducing toxicity to the rest of the body," said Fan Yuan, Ph.D., co-author on the pap...Biomarkers may hone anti-aging therapies
...cludes, as a byproduct, the production of reactive oxygen species, which can damage the DNA present in mitochondria, Sligh said. Some theories of cellular aging -- why and how cells age -- center on mitochondria and decreased energetic capacity resulting from mitochondrial DNA mutations, Sligh explained. I...Oxidation defense in mosquitoes benefits malaria parasite
... condition, stimulating the production of reactive oxygen species, which can damage cells," said Li. Mammals have various biochemical pathways of disposing of 3-HK, which mosquitoes lack. Research by Li's group at Virginia Tech on Aedes aegypti mosquitoes determined that "mosquitoes have developed an effi...Attacking cancer's sweet tooth is effective strategy against tumors
...--a distinct disadvantage since most cells require oxygen to produce the bulk of their energy-storing adenos...y continue to use this pathway even when access to oxygen is restored. Though the so-called Warburg effect has since been confirmed, the role played by glyco...New MRI technique shows emphysema in asymptomatic smokers
...rease, cavities form in the lung tissue, hindering oxygen delivery. According to the American Lung Association, over 3 million people in the United States have been diagnosed with emphysema, and millions more are in the early stages of the disease before signs and symptoms appear. Smoking cigarettes triples...New tool tracks brain development in babies
...emia, a type of brain injury caused by a period of oxygen and nutrient deficiency, usually as a result of complications during delivery. Hypoxic ischemic injury can result in severe motor problems. "The pattern and extent of the brain injury largely determine the neurological and developmental consequences...Marine 'dead zone' off Oregon is spreading
...st to the central Washington coast. Some dissolved oxygen levels at 180 feet have recently been measured as ...ve been measured at 1 milliliter per liter. These oxygen levels are several times lower than normal, and any dissolved oxygen level below 1.4 milliliters per...Delft water-purification method promises radical improvement
...nular sludge technology (Nereda TM), aerobic (thus oxygen using) bacterial granules are formed in the water that is to be purified. The great advantage of these granules is that they sink quickly and that all the required biological purifying processes occur within these granules. The technology therefore ...Viagra improves high altitude exercise performance up to 45% for some
... Sildenafil also minimized the decline of arterial oxygen saturation of the arteries when the cyclists were ...s improves blood flow from the heart and increases oxygen transport to working muscles. Because the high altitude atmosphere contains less oxygen, it is more ...DOE JGI finishes 100th microbial genome
...yll biosynthesis, photosynthetic light harvesting, oxygen tolerance, and many other aspects of the physiology and metabolism of the green sulfur bacteria." The search for microorganisms that can inform solutions to energy and environmental challenges can go to the extremes--the boiling hot pools in Yellows...... Water covering the rice plant reduces the plant's oxygen and carbon dioxide supplies, affecting photosynthesis and respiration. Submerged, the plants lack the gases needed to produce sugar for cellular energy, resulting in death if submergence persists beyond four days. Bailey-Serres notes that access t...