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Tag: "overlapping" at biology news

Wisconsin scientists grow critical nerve cells

...tists always believed. Rather, a series of complex overlapping changes may well be the developmental norm in higher vertebrates such as humans. "We cannot simply translate studies from animal to humans," says Zhang. The next step, Li says, will be to test if the newly generated neurons can communicate with oth...

New, automated tool successfully classifies and relates proteins in unprecedented way

...w tool outperformed existing methodsof identifying overlapping proteins within cells, such as simple visualcategorization of their locations."Our tool outperformed clustering based on the terms developed by theGene Ontology Consortium, the best previous way of describing proteinlocation. We found that the Gene O...

New Study from Affymetrix Laboratories Points to Changing View of How Genome Works

...ands of regions of the genome are transcribed into overlapping RNA sequences and those sequences are separated by... regions of the genome, creating a complex pool of overlapping transcription. While the team validated many known protein-coding transcripts that contribute to thi...

Hirsute Or Hairless? Two Proteins May Spell The Difference

...ells into a hair bud. During the budding process, overlapping signaling pathways from two adjacent embryonic cell layers—the epithelium and the mesenchyme—direct morphogenesis. The mesenchymal cells initiate the cell-to-cell “crosstalk?that controls bud formation by first directing a small cluster of epithelial...

Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection

...pecies with similar amino acids sequences share an overlapping set of shapes, which helps explain why species with shared sequences have the ability to infect each other. Surewicz says the next step in their research will be to examine fibril shape differences at much higher resolution. Their experiments also u...

Researchers rein in regulatory RNAs

...ansport, and translation. Various examples of such overlapping genes have been documented in all life forms ?from...few have experimentally validated the existence of overlapping RNA molecules in vivo. With this in mind, Dr. Hidenori Kiyosawa, the lead author on the paper, set o...

Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression

...rowth. Humans and other animals have evolved many overlapping ways of controlling gene expression. Many different controls determine when a DNA gene is transcribed into mRNA, and when and how the mRNA is translated into a protein. Many proteins are also tightly controlled through various post-translational modi...

Decoding the logic of olfaction

...and chocolate. Revealing these distinct ?but often overlapping ?patterns of neural activity represents a significant step in understanding how the brain translates complex signals from odorant receptors in the nose into odor perception in the brain, the researchers said. The research team, which was led by HHMI...

Genpathway and Baylor College of Medicine Identify New Genes in Breast Cancer

...and chocolate. Revealing these distinct ?but often overlapping ?patterns of neural activity represents a significant step in understanding how the brain translates complex signals from odorant receptors in the nose into odor perception in the brain, the researchers said. The research team, which was led by HHMI...

Scientists discover that three overlapping signals in embryo help get the backbone right

...ly embryonic development are so critical that many overlapping signals are needed to ensure that cells go down the right path. The formation of the back and belly is a milestone for frogs as well as for humans and other vertebrates, occurring as it does at the beginning of the process of gastrulation, which sees...

New technology shows our ancestors ate…everything!

...ed variability in the samples for each species and overlapping data for the two species. The researchers say this suggests that both species relied on their less preferred foods during periods of food scarcity. "If members of a species live in a seasonal environment, they can get all the soft fruit they need dur...

Scientists crack 40-year-old DNA puzzle and point to 'hot soup' at the origin of life

...acids emerge naturally in the table, evolving from overlapping 'prefix' and 'suffix' codons. "When you evolve our theory for a doublet system into a triplet system, you get an exact match up with the number and range of amino acids we see today," said Dr van den Elsen, who has worked with Dr Stefan Babgy and Hu...

Fitting in: Newly evolved genes adopt a variety of strategies to remain in the gene pool

...better explained with an array of different, often overlapping functional roles." Yeast metabolism provides an ideal model for investigating the functional basis for gene duplication because a large proportion of genes involved in this biological process have been duplicated. Of the 672 genes involved in yeast...

Engineers discover why toucan beaks are models of lightweight strength

...vered by a shingled roof, the foam is covered with overlapping keratin tiles, each about 50 micrometers in diameter and 1 micrometer thick, which are glued together to produce sheets. The study in Acta Materialia also noted a hollow region extending about half the length of the upper and lower beak. "When we di...

UCSD study finds anthrax toxins also harmful to fruit flies

...ctivities of several related proteins that perform overlapping functions in other diseases or biological processes. Such experimental tools could accelerate progress in various areas of biomedical research. Guichard first conceived this study in 2002, to apply her experience in molecular genetic studies to res...

Novel molecular 'signature' marks DNA of embryonic stem cells

...nome, the scientists discovered an unusual pair of overlapping molecular tags in the chromatin structure, which together comprise what they called a "bivalent domain," reflecting the dual nature of its design. These domains reside in the sections of chromatin that control the most evolutionarily conserved portio...

Scientists win grants to develop $1,000 genome sequencing technology

...reassemble the chromosomes by piecing together the overlapping ends of all the fragments after they have been sequenced. Bioengineering professor Michael Heller is a third member of the UCSD team. He is an expert on using electric fields to actively manipulate biomolecules and assemblies of nanostructures. H...

Scientists design simple dipstick test for cocaine, other drugs

...vices." The lateral flow device consists of four overlapping pads ?wicking, conjugation, membrane and absorption. The appropriate aptamer-linked nanoparticle aggregates are placed on the conjugation pad, streptavidin is applied as a thin line to the membrane pad, and the device is then dried. When dipped int...

Scientists reveal structure of gateways to gene control

...nscription-promoter control centers occupy several overlapping positions on the DNA molecule, typically 10 base pairs apart, which exactly matches the periodic rotation of the DNA double helix. "It is striking how well these positions match with the architecture of the DNA as it wraps around the nucleosome's pr...

Mosquito genes explain response to climate change

...l photoperiodism. Two of the chromosomes also have overlapping gene expression that tells the species to go dormant, which they must do to survive. "This chromosomal map is drawing a lot of interest in terms of understanding the genetic response of animals to rapid climate change and also to understanding th...

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