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Tag: "overcome" at biology news

Cancer stem cells linked to radiation resistance

...amage checkpoint response in cancer stem cells may overcome the radiation resistance and eventually allow us to help even greater numbers of cancer patients." ...

Pilot study successful in taming allergic reactions to food

...who were allergic to eggs were able to essentially overcome their allergy by gradually consuming increased quantities of eggs over time, researchers at Duke University Medical Center and the University of Arkansas for Medical Sciences have found in a small pilot study. “Participants who took a daily dose of...

New moth variety disarms plants guarded by selenium

...accumulating high levels of a toxic element can be overcome by some insects, and that such adaptation potentially echoes in the food web as other predators and parasites may in turn evolve to deal with high levels of the toxic element. The findings, reported by Elizabeth Pilon-Smits of Colorado State Universi...

High tech help to prevent further heart disease

...patients in an easy-to-use interactive format will overcome many of the barriers. Chair of MBF Foundation’s Steering Committee, Dr Christine Bennett, said that this easy access, high quality rehabilitation service can deliver better community health outcomes by guiding patients to make healthy and positive...

Stanford discovery may help predict when toxoplasma can be deadly

... notably half of humanity. Its unusual ability to overcome the numerous challenges of infecting and reproducing inside such a wide range of creatures has long intrigued scientists, and now researchers at the Stanford University School of Medicine have identified two of the proteins critical to its ability...

Report calls for improved monoclonal antibodies against solid tumors

...to illustrate that the groundwork has been laid to overcome these barriers. Researchers, including Dr. Weiner, have made significant advances to understand the optimal antibody affinities required for maximum penetration, even taking into account tumor size. Studies have also investigated the optimal antibody...

U-M researchers use nanoparticles to target brain cancer

...ature with nanoparticles containing a payload will overcome these issues," says study author Alnawaz Rehemtulla, Ph.D., professor of radiology and radiation oncology at the U-M Medical School and professor of environmental health sciences at the School of Public Health. Treating brain tumors is traditiona...

Distinguishing friend from foe in the battle against cancer

...o stay alive and in doing so suggest a strategy to overcome their recalcitrance. The study, led by Tony Hunter, Ph.D., in collaboration with Inder Verma, Ph.D., shows that resistance to the chemotherapeutic drug rapamycin is mediated by the survival factor NF-kB. Rapamycin, like the pharmaceutical superstar ...

HIV gets a makeover

...st in the lab and the paper's first author, had to overcome two major obstacles: the first was a protein called TRIM5 that, in monkeys, recognizes the outer shell or "capsid" of HIV-1 but not that of SIV. By swapping out the capsid region of the HIV-1 genome for that of the monkey virus, and then selectively ...

Scientists win grants to develop $1,000 genome sequencing technology

...ming the daunting technical obstacles that must be overcome to develop a $1,000 genome technology," said Huang. "Sequencing a genome in a few days for only $1,000 is an enormously challenging task, but I think we have as good a chance as any group to get there first." Huang's group was awarded $275,000 for on...

The effects of smoking on fractures and ligament injuries

... speed the healing process, as well as potentially overcome the deleterious effects of smoking on ligament healing." ...

Mutant gene causes severe kidney disease in infants

... a critical time window during which treatment can overcome the development defects caused by PLCE1's loss of function." The discovery has important implications for pediatric nephrologists and pediatricians who treat infants with nephrotic syndrome, according to Hildebrandt. "In very early-onset nephr...

Molecular atlas provides new tool for understanding estrogen-fueled breast cancer

... that are most likely to be effective for them and overcome the problem of resistance to current hormone therapies, the study authors say. The estrogen receptor (ER) is an intricate protein net in the nucleus of breast cancer cells. When the receptor snares an estrogen molecule, it sets in motion a cascade ...

Early-stage immune system control of HIV may depend on inherited factors

...nd implies that a successful vaccine would have to overcome genetic factors associated with a less protective response," he adds. Altfeld is an associate professor of Medicine at Harvard Medical School. He and his colleagues are working on a follow-up study with samples from 500 individuals to further invest...

T-ray breakthrough could make detecting disease far easier

...allow T-rays to flow along it, but our idea was to overcome this by corrugating its surface with a series of grooves, in effect creating an artificial material or 'metamaterial' as far as the T-rays are concerned." "In this way, the T-rays can be focused to the tip of the wire and guided into confined spac...

Coated nanoparticles solve sticky drug-delivery problem

...t: they can also keep helpful medications away. To overcome this hurdle, Johns Hopkins researchers have found a way to coat nanoparticles with a chemical that helps them slip through this sticky barrier. During experiments with these coated particles, the researchers also discovered that mucus layers have...

Neural bottleneck found that thwarts multi-tasking

...ion about how that area responds over time. To overcome this limitation, Dux and Marois rapidly sampled brain activity using fMRI while subjects were performing two demanding tasks. Evaluation of the data produced by this rapid sampling method allowed them to characterize the temporal pattern of activity ...

Birth rate, competition are major players in hominid extinctions

...ndertal, cultural adaptation was not sufficient to overcome and compete with modern humans, just as Paranthrop...ulation density, or come up with new technology to overcome the problems we will face from the global climate change we have created? "We clearly have the cu...

Elderly spinal cord injuries increase five-fold in 30 years, Jefferson neurosurgeons find

...cal illnesses, as well as their limited ability to overcome traumatic injuries, they said. Mortality, both during hospitalization and the first year after injury, was much higher in the geriatric population-- approximately eight times higher, the study showed. Mortality during hospitalization...

Scientists unveil piece of HIV protein that may be key to AIDS vaccine development

...flexible nature of the chemical bonds in gp120. To overcome the problem, the investigators created a variety of gp120s and eventually made the protein stiff enough to capture a picture of it in complex with b12. They saw that b12 binds gp120 at the same point where gp120 initially attaches to CD4. Unlike the ...

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