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Tag: "overcome" at biology news

Neurons grown from embryonic stem cells restore function in paralyzed rats

...stance called dibutyrl cAMP (dbcAMP) that helps to overcome axon-inhibiting signals from myelin, the substance...re is nothing left to protect," says Dr. Kerr. "To overcome the loss of function, we need to actually replace lost neurons." While these results are promising,...

PTEN: the Treg's handbrake

...o IL-2 and could provide researchers with a way to overcome one of the biggest obstacles to harnessing their therapeutic potential. ...

Experimental RNA-based drug kills prostate cancer cells effectively and safely

...nimal side effects, and it shows it is possible to overcome many of the obstacles that have hampered the development of RNA-based drugs." The study is reported in the August 2006 issue of Nature Biotechnology, which is now available online. The research was funded by the National Institutes of Health. Du...

Defense peptide found in primates may block some human HIV transmissions

...ting blood cells. HIV-1 often mutates quickly to overcome antiviral compounds designed to prevent infections. But a research team led by Associate Professor Alexander Cole of UCF's Burnett College of Biomedical Sciences has demonstrated that over 100 days the virus develops only weak resistance to retrocycl...

Hopkins scientists show hallucinogen in mushrooms creates universal 'mystical' experience

...ebo. In designing the study, researchers had to overcome or at least, greatly minimize two hurdles: the risk of adverse side-effects and the likelihood that the expectations of getting the test drug or the placebo would influence subjects' perceptions. To lessen the former, each subject met several time...

Science captures the essence of fruit

... produce the desired outcome. HortResearch has now overcome this issue by using research initially intended to speed up the process of fruit breeding, says Dr Newcomb. "Through decades of fruit breeding research HortResearch has developed extensive fruit gene and compound databases. Now we have developed te...

The brain, traffic and nano-circuits -- e-Science takes on major challenges

...esigners to remain internationally competitive and overcome the disadvantages caused by the lack of an indigenous UK semiconductor industry. ...

Trials for new drug to overcome HIV

A new drug that could help overcome HIV�fs growing resistance to existing antiviral dr...existing drug regimes are failing. PA-457 aims to overcome this resistance by attacking HIV on new front. Many existing drugs work by blocking reverse transcri...

Copying nature could save us energy, study shows

...ies that mimic the way insects, plants and animals overcome engineering problems could help reduce our depende... has compared how nature and man-made technologies overcome similar problems has shown that only 5 per cent of natural 'machines' rely on energy in the same way...

Serotonin, acting in a specific brain region, promotes sleep in fruit flies

...ted sleep, suggesting that serotonin treatment can overcome some deficits caused by other sleep problems. The researchers also identified a serotonin receptor that affects sleep, and showed that it acts in a specific region of the fly brain known as the mushroom bodies. Interestingly, the mushroom bodies are ...

Scientists use gene signatures to match cancer and other diseases with potentially effective drugs

...the method successfully identified a drug that can overcome therapy-resistant cases of acute lymphoblastic leukemia (ALL) in children. So-called "glucocorticoid" drugs like prednisone are very effective in many cases of ALL, but in some patients the cancer cells are resistant to the drugs, which often can lea...

Where we change our mind

...obabilistic analysis of the subjects' movements to overcome a major obstacle to such studies. That obstacle is that the beliefs of the subjects during the experiment could not be determined unequivocally; thus, those beliefs could not be correlated with brain function. However, the researchers' statistical a...

Genetic 'roadmap' charts links between drugs and human disease

... cell. Another key finding suggests a new way to overcome drug resistance in cancer. Using the Connectivity Map, a scientific team led by Scott Armstrong, an assistant professor at Harvard Medical School and Children's Hospital Boston and an investigator at the Dana-Farber Cancer Institute, identified the F...

Stem cell expansion

...ain enough of them for a successful transplant. To overcome this limitation, Hans-Peter Kiem and colleagues have developed a way to expand HSCs in the laboratory prior to transplantation. As they report in the international open-access journal PLoS Medicine, expression of a gene called HOXB4 can instruct ste...

Embryo tests give parents the choice

...any other cancers. PGD was originally intended to overcome infertility and to ensure that all children are born with achance of a full and flourishing life, says Eric Cohen, head of the bioethics programme at the Ethics and Public Policy Center in Washington DC. "PGD clinics are performing sex selection just...

Inflammation markers identify fatigue in breast cancer survivors

...cer survivors are the largest group of patients to overcome any type of cancer in the United States. While patients surviving other types of cancer also can experience the long-lasting fatigue syndrome, a greater proportion of breast cancer survivors endure the condition. Cancer researchers had explored var...

A transplant in time

...ether human or pig, could one day help the body to overcome genetic diseases. ...

UGA scientists unravel 'molecular inch-worm' structure of walking-pneumonia bacterium

...e works gives us a new edge in thinking of ways to overcome such infections." ...

St. Jude finds clues to hearing loss from chemotherapy

...y to manipulate or replace those genes in order to overcome those problems." Individual mutations might disrupt the work of a cascade of genes that cooperate to construct certain nerves or sections of the inner ear that sense sound; that stimulation is then turned into electrical impulses that go to the hear...

Restoring tamoxifen sensitivity in resistant breast cancer cells

... Director John E. Niederhuber, M.D. "Being able to overcome resistance would be an important advance." In the study, the research team, led by William Farrar, Ph.D., of NCI's Center for Cancer Research at Frederick, Md., found that the effectiveness of tamoxifen in cell cultures and in mice can be fully res...

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