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Tag: "overcome" at biology news

W.M. Keck Foundation funds study of friendly microbes

...d itself to funding high-risk projects designed to overcome key obstacles in emerging fields in science so that rapid progress can subsequently be made," Gordon says. "Their support of our studies of the genomic and metabolic foundations of mutually beneficial (symbiotic) relationships between microbes and hu...

Columbia research lifts major hurdle to gene therapy for cancer

... University MedicalCenter have discovered a way to overcome one of the major hurdles ingene therapy for cancer: its tendency to kill normal cells in theprocess of eradicating cancer cells.In a new study published in the Jan. 25 issue of the Proceedings of theNational Academy of Sciences (PNAS), the researcher...

U-M scientist to talk about tissue engineering at AAAS

...amp up the effects. "Together these therapies can overcome compromised environments," he said. "Combining therapies can help us overcome some of the complications of current therapies, too." These approaches are not yet being tested in ...

Breakthrough Microarray-based Technology for the Study of Cancer

...microarray platform that uses total genomic DNA to overcome severalscientific hurdles that previously impeded ...hput. Efforts inrecent years to use microarrays to overcome these limitations have beenhampered by inadequate sensitivity, specificity and flexibility of themic...

Genetically modified natural killer immune cells attack, kill leukemia cells

...sue of Blood. The researchers demonstrated how to overcome significant technical hurdles that have until now slowed development of NK-based therapies for ALL, according to Dario Campana, M.D., Ph.D., a member of St. Jude Hematology-Oncology and Pathology, and senior author of the Blood report. Progress in ad...

X-Ray Beams And Fruit Fly 'Flight Simulator' Aid Scientists' View Of Muscle Power

... face an enormous task ?generating enough power to overcome gravity, air resistance and drag ?and they do this by beating their wings ferociously,?said Maughan. “We found out that timing is key, where certain molecules have to be positioned exactly with respect to others during each phase of the wing beat in ...

Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection

...ls with different prion amino acid sequences could overcome species barriers. For instance, mouse prion fibrils normally infect humans but not hamsters. But when mouse prions were brought into contact with hamster prion amyloid fibrils, a new strain of mouse fibrils emerged with the ability to infect hamsters...

Researchers make gains in understanding antibiotic resistance

... clinical impact. The general strategy of Rib-X to overcome resistance is to create new hybrid antibiotics that possess the ability to bind to interact simultaneously with different, nearby sites on the ribosome represented by different classes of antibiotics," he said. "The idea is to take a bit of one anti...

Revolutionary nanotechnology illuminates brain cells at work

...t Biology and Stanford University are the first to overcome this obstacle by successfully applying genetic nanotechnology using molecular sensors to view changes in brain chemical levels. The sensors alter their 3-dimensional form upon binding with the chemical, which is then visible via a process known as fl...

Two are better than one

..., as well as provide ways to sensitize patients to overcome inherent or acquired resistance to cancer treatment," says Yarden. Prof. Yosef Yarden's research is supported by the Y. Leon Benoziyo Institute for Molecular Medicine; the Dolfi and Lola Ebner Center for Biomedical Research; the J & R Center for...

Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells

...sue of Blood. The researchers demonstrated how to overcome significant technical hurdles that have until now slowed development of NK-based therapies for ALL, according to Dario Campana, M.D., Ph.D., a member of St. Jude Hematology-Oncology and Pathology, and senior author of the Blood report. Progress in ad...

Cerebral navigation: How do nerve fibers know what direction to grow in?

...ible targets within axons that could be blocked to overcome this inhibition. Such intervention could possibly enable damaged axons to regenerate (normally impossible in a mature nervous system) and ultimately restore nerve function. It's been known that cells synthesize an inhibitory protein called ephrin, w...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

...cific tumor sites, while avoiding degradation. To overcome these hurdles, the scientists employed a sugar-containing polymer invented by chemical engineers at the California Institute of Technology. For this experiment, the polymer binds to and condenses the engineered siRNA into nanoparticles that, in effec...

Roots Engage in Underground Chemical Warfare

...rabidopsis, has a seemingly fail-safe mechanism to overcome the plant's defenses. The bacterium not only survives exposure to the antimicrobial substances, it also blocks the plant's ability to produce them. Both Vivanco and Ausubel are supported by separate awards from the division of Molecular and Cellular...

Doctors closer to using gene analysis to help trauma patients

...rimental clinical settings ?an important hurdle to overcome before the method is routinely used in emergency rooms and intensive care units. In a report published today (March 7) in the Proceedings of the National Academy of Sciences, researchers from eight institutions, including the University of Florida, ...

Taking the piste out of Alpine vegetation

...ssible, as it causes lasting damage that cannot be overcome by revegetation measures, particularly at higher altitudes," they say. They also measured the impact of artificial snow on vegetation and found that this causes changes in species composition, with snowbed and late-flowering species increasing in ab...

Gladstone investigators discover how resting T cells avoid HIV infection

...f A3G that only occurs in activated T-cells can be overcome by Vif. The results have launched the search for a new class of antiviral drugs that block the action of Vif, which would leave A3G poised and able to unleash its antiviral effect from inside viral particles. In resting T cells, though, HIV is defen...

Sugar beet virus mutation requires Texas touch

...t why this genetically mutated pathogen is able to overcome the resistance in the plant," he said. "We're looking at new crosses by seed companies and challenging them with each of these two viruses, as well as a combination of the two." By measuring the effect of the disease on the plant, as well as purifyi...

An (ecological) origin of species for tropical reef fish

...rriers, indicates that local speciation events may overcome the homogenizing effect of migration in the ocean, vindicating Darwin's original ideas about the importance of ecological speciation in biodiversity evolution. ### Ref: Luiz A. Rocha, D. Ross Robertson, Joe Roman, and Brian W. Bowen. 2005. Ecologic...

Researchers pioneer new gene therapy technique using natural repair process

...here is no correct version naturally available. To overcome this, researchers also supplied the cells with a correct version of the IL-2R gene along with the enzyme. Given the correct copy as a template, the recombination event occurred at the break site and 11 percent of the cells tested had traded one copy...

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