Fertility hope as study shows eggs survive in older ovaries
...ductive cells called oocytes (eggs) develop within ovarian follicles. In humans, the eggs are believed to die...ns. "But the mechanism could provide direction for ovarian stem cell research and help women with fertility conditions," he said. One in six Australian couple...Promising cell protein may play role in infection and dry eye
... good prognosis in breast cancer, small cell lung, ovarian cancer, and inhibition of metastasis. PAI-2 also plays a role in inflammation on the surface of the eye. In their study, the Penn and Temple researchers demonstrate for the first time an interaction between PAI-2 and the tumor suppressing gene Rb2/p...Recombination protein dynamics observed with single monomer resolution
...se mutation increases susceptibility to breast and ovarian cancers. A better understanding of how these proteins function could help our understanding of cancer. "Our measurement technique provides a way of counting the number of individual monomers bound to DNA in real time," said Taekjip Ha, a professor o...Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial
...h packaged in a tiny sphere penetrates deeply into ovarian cancer tumor cells, stifling a troublesome protein... team took siRNA that targets a protein that helps ovarian cancer cells survive and spread and rolled it into a liposome -- a lipid ball so small that its dime...New findings offer more complete view of breast cancer gene mutations in US population
...ing breast cancer, as well as an increased risk of ovarian cancer. To date, most of the studies on BRCA1 a...tations were: Jewish ancestry, a family history of ovarian cancer and a family history of breast cancer occurring before age 45. For BRCA2 mutations, researc...Mass. General study finds potential ovarian cancer stem cells
...spital (MGH) researchers have identified potential ovarian cancer stem cells, which may be behind the difficu...ese cells could lead to new approaches to treating ovarian cancer, which kills more than 16,000 U.S. women annually and is their fifth most common cause of can...Study finds how organs monitor themselves during early development
...unraveled the signals in a feedback loop governing ovarian development. This work has been several years in the making and is being published on 27 August in the Advance Online issue of the journal Nature. "I think our study has indeed important implications that extend beyond understanding of how a gonad...Researchers find molecular 'brake' to cell death
... become resistant to therapy, such as melanoma and ovarian tumors, do so because they have found ways to prevent mitochondria from releasing a lot of CC, he says. Tumor cells also don't want to decrease their nucleotide pool, because they need ATP for continued functioning, he says. "An optimal cancer thera...New device could cut chemotherapy deaths
...e first clinical trials on volunteer patients with ovarian cancer in Avon, Somerset and Wiltshire could begin..."Although the first study will be on patients with ovarian cancer, soon we hope that other cancer sufferers with solid tumours will benefit. "Give that around...VCU Massey Cancer Center researchers identify a new class of anti-cancer drugs based on platinum
...ar platinum compound. In a laboratory model, human ovarian cancer cells were exposed to each drug. "In plat...iven for the treatment of metastatic testicular or ovarian cancers, and some advanced bladder cancer, and is a very effective drug in combination with other th...Genome changes tracked during multiple myeloma initiation, progression and treatment
...malignancies such as pancreatic, lung, breast, and ovarian cancer and may thus represent a rite of passage for many different cancers. "This integrated and detailed view of the MM genome is consistent with the concept of widespread changes in the expression of genes with cancer activity in the pathogenesis...How can we protect patients with weakened immune systems from influenza?
...ncer originating in bone marrow) and patients with ovarian cancer receiving an experimental treatment--an anti-cancer vaccine made from dendritic cells. Carl June, M.D., director of translational research at Penn's Abramson Cancer Center, leads both projects. A third group of adult patients suffers from au...Basic research leads to a novel cancer therapy
...neck tumours, liver cancer, lung cancer, melanoma, ovarian cancer, pancreatic cancer, prostate cancer, and te...ations in the cells of certain forms of breast and ovarian cancer. It blocks the receptor Her2/neu in these cells, which thereby stop growing and become more s...A surprising pair of proteins help make healthy eggs
...possible drug targets for treating infertility and ovarian cancer. "Thousands of women in this country under...f female mice. Without this protein, egg-producing ovarian follicles didn't develop properly. The result: infertile mice. The new research underscores TAF4b's...New nanosensor uses quantum dots to detect DNA
...ng a sample of DNA containing a mutation linked to ovarian cancer. The Johns Hopkins team described the new ...ang's team obtained DNA samples from patients with ovarian cancer and detected DNA sequences containing a critical mutation. "This method may help us identify ...Gene expression profile helps predict chemotherapy response in ovarian cancer patients
...file could help predict how patients with advanced ovarian cancer will respond to chemotherapy treatment. Des...ne profiling as a predictor of clinical outcome in ovarian cancer, and could eventually provide clinicians with insights into the mechanisms of drug resistance......nvestigation are involved in hereditary breast and ovarian cancers and have also been linked to other types of cancers. Rapid diagnosis of infectious diseases?/B> Scientists at the Universities of Bath and Glasgow, with colleagues from Stobhill Hospital and Atlas Genetics Ltd are miniaturising establis...Anti-cancer Compound In Beer Gaining Interest
...ies. It showed toxicity to human breast, colon and ovarian cancer cells, and most recently has shown some activity against prostate cancer in OSU studies. Xanthohumol appears to have several mechanisms of action that relate to its cancer preventive properties, scientists say. It, and other related flavonoid...Renewed hope for Parkinson's patients
...ignificant role." The researchers put cultures of ovarian epithelial cells and fibroblasts from mice through a battery of abuse, including heat shock, pH changes, oxygen deprivation and starvation. However, the only type of stress that set off the sequence of events associated with impairment of a cell's ge...New study finds how cells with damaged DNA alert the immune system
...ignificant role." The researchers put cultures of ovarian epithelial cells and fibroblasts from mice through a battery of abuse, including heat shock, pH changes, oxygen deprivation and starvation. However, the only type of stress that set off the sequence of events associated with impairment of a cell's ge...