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Tag: "outside" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

...ts of five concave surfaces, or bowls: four on the outside and one on the bottom. It has an open top, much like an open-air stadium. Its general molecular formula is C268H320O52. The tiny molecules can be modified to include other functional groups that give it additional properties, Sherburn says. For inst...

Bioartificial kidney under study at MCG

... a second cartridge, while the blood is run on the outside of the fibers. "(These cells) reabsorb substances...afiltrate ?and put them back into the blood on the outside of the fiber, which is pumped back into the body. The stuff that isn't pumped out is just like urine...

Genes In The Interferon System Important In Systemic Lupus Erythematosus

...hose function is to convey signals from interferon outside the cellsto the cell nucleus."We found that genetic variants of thyrosinkase protect against SLE. Itprobably has an inhibited function that blocks the interferon effect.It is therefore possible to imagine the development of methods oftreatment for SL...

W.M. Keck Foundation funds study of friendly microbes

...eria are difficult or impossible to grow and study outside of the intestine. With the support provided by the... or treating a variety of diseases both inside and outside of the gastrointestinal tract." ...

Controversial drug shown to act on brain protein to cut alcohol use

...lcohol andvarious drugs of abuse. It has been used outside of the U.S. to treataddiction by American and other clinicians. But its side effects,including hallucinations, which made it popular in the 1960s drugculture, and evidence of toxicity to certain nerve cells in rodentstudies have discouraged careful s...

Researchers Uncover Key Step In Manufacture of Memory Protein

...BDNF. After mBDNF is formed, it is released to the outside of the neuron, where it binds to receptors on other neurons and stimulates them to form long-term memory. Dr. Loh explained that, like other proteins, proBDNF is made inside the endoplasmic reticulum, a convoluted network of tubes and channels insid...

Scientists Replicate Hepatitis C Virus in Laboratory

...els of viral particles resembling fully-formed HCV outside of the human liver cells in the culture medium. The researchers believe that the HCV construct contained within the human liver cells behaved like a true HCV infection by producing fully formed copies of the virus and releasing them from the host cel...

A much-needed shot in the arm for HIV vaccine development

...nore the important contributions madeby scientists outside of the collaboration. "It is my contention thatgreat new ideas are as likely to come from curiosity-driven basicstudies as from the mission-oriented approach that is represented bythe new proposal."The PLoS Medicine editors hail the plan as being a "...

Research on Worms Yields Clues on Aging

...f an insulin-like hormone. "Sensory inputs fromthe outside regulate the level of insulin signaling inside the body,which then in turn regulates longevity in the worms," Kornfeld says.Testing the anticonvulsants on longer-lived mutant worms, theresearchers found the drugs further extended their lives, althoug...

Dinosaur DNA? New Patent Covers Degraded DNA recovery

...ng genetic history. We now have the picture on the outside of the puzzle box, and by stringing together the pieces of aged DNA, we should be able to reconstruct genes from animals such as the wooly mammoth, giant sloth, saber-toothed cat or even from tissues of the Tyrannosaurus rex that was described last F...

Mitochondrial DNA mutations play significant role in prostate cancer

... hundreds of mitochondria located in the cytoplasm outside ofeach cell's nucleus. The mitochondria often are called the "powerhouse"of the cell because they produce about 90 percent of the body's energy.John A. Petros, MD, associate professor of urology and pathology atEmory University School of Medicine and...

Purdue proves concept of using nano-materials for drug discovery

... the alumina membranes - and the liquid was placed outside each vessel so that it covered the opposite side of the membranes. When the liquid diffused through the membrane's pores, it mixed with the enzyme, causing a reaction and turning blue in the process, which demonstrated that the device works. The Cen...

Taking Aim With Nanoparticle PEBBLEs

...the cells they target. Instead, they attach to the outside of the targeted cell and shoot reactive oxygen spe...an avalanche of damage," said Kopelman. By staying outside the cell, PEBBLEs avoid a problem that thwarts many chemotherapy drugs. "The really bad cancer cell...

Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer

...tein, which thedendritic cells then display on the outside of their cell surface. Thisis, in fact, a neat trick, says Lachman, because the function ofdendritic cells is to flag the immune system by presenting “antigen,?or pieces of a foreign invader, to activate an immune response. “Sonow, the same immune sy...

A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020

...tein, which thedendritic cells then display on the outside of their cell surface. Thisis, in fact, a neat trick, says Lachman, because the function ofdendritic cells is to flag the immune system by presenting “antigen,?or pieces of a foreign invader, to activate an immune response. “Sonow, the same immune sy...

Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells

...ction of cells but becomes malicious, tries to get outside the area, and hijacks the respiratory machinery of a cell." The biocavity laser It is these changes - a kind of beefing-up of the criminal forces - that Gourley's device, called a biocavity laser, detects. A nano-thin layering of gallium aluminum ...

Simple drug has the potential to save many lives threatened by malaria

...alaria in Africa. The majority of fatalities occur outside hospital, especially in rural areas. For those who... given by injection, is not possible to administer outside hospital, so buying time by starting treatment which is easy to administer in the community is cruci...

Study of genomic DNA leads to new advances in cancer diagnostics

... any of three cytoskeletal systems, which link the outside of the cell to the genome. Using this information, Dr. Maniotis's group developed a new kind of extracellular matrix chip (patent pending) that is being used to study drug-resistance mechanisms to develop new protocols and methods to treat cancer. U...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

...rointestinal tumorigenesis, in that genetic events outside the epithelial layer itself have a profound effect on tumor initiation. Thus it appears likely that this study will foster additional research into other mesenchymal genetic modifiers, and into potential therapeutic approaches that affect the signali...

South America's vast pantanal wetland may become next everglades, UNU experts warn

...ear round. The analysis says "new landowners from outside the Pantanal frequently apply non-sustainable practices." "Prior to the 1970s, the traditional stakeholders had limited impact on the resources they used and did not have the means to induce major environmental changes, such as altering the flood pu...

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