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Tag: "outcomes" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

... body, potentially resulting in improved treatment outcomes and perhaps saving lives, the researchers say. The molecule also shows promise for a wide range of other applications, including the removal of environmental toxins and aiding in chemical purification procedures, the investigators say. Their study w...

Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer

...tion of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation therapy trial was designed to ...

Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down

...tion of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation therapy trial was designed to ...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...entified, patients with features that portend poor outcomes may soon be treated earlier and more effectively," said Dr. Chiorazzi. "Once these new prognostic markers are clinically available to doctors, and after large-scale trials testing early intervention are completed, the 'watchful waiting' practice may...

Gene variations explain drug dose required to control seizures

...the prescription process, physicians might improve outcomes for patients with epilepsy, said the researchers. A similar approach might also prove useful for other conditions, such as Parkinson's disease and cancer, in which patients' drug dosage requirements vary substantially, they added. Rigorous clinical ...

Research Gives Hope For Liver Damage

...umption, can lead to liver failure. At a time when outcomes forother diseases, such as cancers and heart trouble, have made dramaticgains, liver damage - described as the new plague of the 21st century -has yet to be understood and in turn, to become treatable. More womenin the UK now die of liver failure tha...

MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks

...yzing data and in testinghypotheses with simulated outcomes before testing them experimentally.The predictive capabilities of computer simulations can also aidbiologists in viewing cellular activity over a period of time, bytaking advantage of the power of computers to generate the thousands ofpotential prote...

Kinovate Life Sciences Launches Nittophase?High Performance Solid Support For Oligonucleatide Synthesis

...iver significantly improved technical and economic outcomes for all segments of the oligonucleotide industry. Solid support is the base structure used in the synthesis of oligonucleotides, including diagnostic probes and primers, antisense including RNAi, microRNA, DNA-based and aptamer drugs and represents ...

Expression Project for Oncology (expO) completes first phase of standardized gene expression analyses

...f deidentified tumor samples updated with clinical outcomes and release all data into the public domain without intellectual property restriction. "This publicly accessible gene expression clinical database of patient specimens will fuel and accelerate clinically meaningful and scientifically valid research ...

Alzheimer's cognitive decline slowed

...es were performed without complication. Cognitive outcomes were assessed in the six patients who completed the NGF delivery procedure safely. The Mini Mental Status Examination (MMSE), which evaluates cognitive function, was administered at screening, the time of treatment and at several intervals after trea...

Rare surgery performed to remove pancreas, prevent diabetes

...ances in cadaveric islet cell transplantation made outcomes more favorable. ...

Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells

...nsplantation in newborns yields the best long-term outcomes and newborns tolerate the transplants more easily than older babies and children. "Time is of the essence in treating these children before symptoms progress and become irreversible," said Kurtzberg, director of Duke's Pediatric Blood and Marrow Tra...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

...ts, but despite aggressive treatments, the patient outcomes are poor," said Hu. "The delivery system we're developing can shield the drugs from degradation before reaching the target sites, while delivering siRNA for more specificity and potency so as to lower the required dose for efficacy." The study was ...

Multiple-drug resistant gene expression pattern predicts treatment outcome for pediatric leukemia

...ct populations of patients with inferior treatment outcomes than expression patterns associated with resistance to a single drug. "These findings provide new insights into the biological basis of de novo multiple-drug resistance and illuminate potential new targets for overcoming this cause of treatment failu...

Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells

...nsplantation in newborns yields the best long-term outcomes and newborns tolerate the transplants more easily than older babies and children. "Time is of the essence in treating these children before symptoms progress and become irreversible," said Kurtzberg, director of Duke's Pediatric Blood and Marrow Tra...

Scientists generate patient-specific stem cells, Science study says

... the need to promote realistic expectations of the outcomes of stem cell research. The Korean researchers who performed this stem cell research improved upon their protocols that yielded the first embryonic stem cell line from a cloned human blastocyst. (Science 12 March 2004; 303: 1669-1674; published onlin...

SuperLigands - a database of ligand structures derived from the Protein Data Bank

... the need to promote realistic expectations of the outcomes of stem cell research. The Korean researchers who performed this stem cell research improved upon their protocols that yielded the first embryonic stem cell line from a cloned human blastocyst. (Science 12 March 2004; 303: 1669-1674; published onlin...

Microscopes at microscopic size

...research group leader, said, "Our research and the outcomes from the spin-out company could help to revolutionise how we examine biological samples. Our next step will be to develop simple, small diagnostic devices. Future generations may be able to use these as the basis for hand-held systems that will be ab...

'Smart drug' targets deadly brain cancer

... adults, glioblastoma mutiforme. Current treatment outcomes for this type of cancer are extremely poor: median patient survival is 12 to 16 months, and recurrent disease has a dismal prognosis. The World Health Organization categorizes fast-growing glioblastoma multiforme as a grade IV cancer. Significance o...

Newer imaging techniques may lead to over-treatment

... "our study found no significant difference in the outcomes of patients ruled out for pulmonary embolism with ...r CT examination, but at three and six months, the outcomes were similar," he said. Seeing more can have drawbacks as well, Dr. Prologo said. "If we see the sm...

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