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Tag: "out" at biology news

Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease

... the lab of Stuart Schreiber. Together they worked out techniques to examine the way genes are packaged in yeast. To go from yeast to humans required a technological breakthrough, however. "Most prior studies involved only single genes, but we wanted to investigate entire chromosomes, which contain hund...

First 'atlas' of key brain genes could speed research on cancer, neurological diseases

...nformation from the Human Genome Project, singling out all genes inthe mouse that appeared to be transcription factors: they turned up1,445 of them. Next, they determined that more than 1,000 of these TF’swere expressed in the brains of developing mice.Using genetic probes to investigate thin sections of...

Vital step in cellular migration described by UCSD medical researchers

...iation of activity by Rac that extends protrusions out of the cell. These protrusions serve as tractor sites for migration as the cell moves toward its intended target. If Rac were active throughout the cell, it would extend protrusions in all directions, in essence keeping the cell in one place. Until ...

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

... and in this latest study we were trying to figure out what those speed limits are, especially with regar...paid off in terms of results, he added. "It turns out that clathrin regulates endocytosis in a manner we never suspected before. It's not a linear relatio...

Experiments provide proof of how traveling in groups protects insects

...ore dramatic than when they band together and head out on the march cross-country. Among examples are the...e could keep track of individual crickets and find out what happened to them when they were in the band and also when we removed them and put them in other...

Scientists develop new color-coded test for protein folding

... noting that a gold nanoparticle sensor could turn out to be a quick and inexpensive way for doctors to identify antibodies and other signs of infection in the blood stream. Over the next few months, he and his colleagues plan to re-do the experiment using other protein molecules. ...

Placenta Is A Rich Source Of Blood Stem Cells

...a senior investigator of the study. ''If we figure out what's special about the placental environment, we may learn how to grow blood stem cells in large numbers for clinical application.'' Blood stem cells are used in treating blood cancers like leukemia and other blood diseases, and in patients receiv...

Probing The Promise And Perils Of Nanoparticles

...—to see if they behaved like dendrimers. "It turns out that they cause the same permeability and, in general, they cause membrane destruction as well," said Banaszak Holl. Neutral polymers, however, did not damage membranes. Both Leroueil's work and the earlier research used model membranes to probe the...

Researchers discover molecule that causes secondary stroke

..., she says, was "striking." The researchers point out that although their findings are encouraging in terms of developing a diagnostic test and treatment, the number of patients in their study was small and more work is needed to confirm that vasospasm is more likely to occur in bleeding-stroke patients...

Researchers find missing genes of ancient organism

...egions, termed introns, are sequences that are cut out of whole gene transcripts during the process of tRNA maturation. The known tRNA introns in organisms like yeast, however, appear to have no function. Therefore, modern tRNA introns might be remnants of an old essential process of tRNA biosynthesis. ...

Same mutation aided evolution in many fish species, Stanford study finds

...hers sometimes need to put on the hip waders, pull out the fishing net and go learn how their theory comp...t genetic alteration. The group continues to wade out into nature, collecting additional stickleback species from around the world that can reveal whether...

Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra

...asslands to scrubby, low-growing tundra. It turns out that the nutrient-poor volcanic soils of the Aleut...n, and USFWS biologist Vernon Byrd. The study grew out of conversations between Estes, who has been doing research in Alaskan coastal waters for decades, a...

Researchers trace evolution to relatively simple genetic changes

... forehead and nose. Now, Kingsley said, "it turns out that armor plate patterns in the fish are controll...s naturally in the wild," he noted. "And it turns out that the mechanisms are surprisingly simple. Instead of killing the protein (with mutations), you me...

Scientists reveal molecular secrets of the malaria parasite

...perial College in England, where scientistscarried out gene expression studies; and The Institute for GenomicResearch (TIGR), in Maryland, where scientists did a comparativeanalysis of the two draft genomes with those of the first rodentmalaria parasite to be sequenced, Plasmodium yoelii.The first author...

Octopuses occasionally stroll around on two arms, UC Berkeley biologists report

... forehead and nose. Now, Kingsley said, "it turns out that armor plate patterns in the fish are controll...s naturally in the wild," he noted. "And it turns out that the mechanisms are surprisingly simple. Instead of killing the protein (with mutations), you me...

Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers

...off their respiratory systems periodically to keep out excess oxygen, thus preventing damage to their tis...ply oxygen to our tissues, but they must also keep out excess oxygen to prevent oxidative damage to the tissues. This damage is closely related to aging. H...

Alcohol's effects on gene expression in the central nervous system

... as brain damage. "The challenge has been to find out which genes ?out of more than 50,000 ?are turned on or off in the brains of alcoholics," he said. "Microarray studies ?the examination of a small glass microscope slide that has thousands of different DNA samples attached to it ?that are applied to b...

Research Gives Hope For Liver Damage

...have shown how the macrophageswork, we aim to find out how to create, activate and de-activate thesecells to make them repair, rather than damage, liver tissue."He added: "Cirrhosis, commonly, but not always, caused by alcoholconsumption, can lead to liver failure. At a time when outcomes forother diseas...

New SARS Protein Linked To Important Cell Doorway

...t reproduced viral proteins as they make their way out of the cell. The finding exemplifies a primary di...s' ability to survive and reproduce. "If knocking out orf7a significantly attenuates the virus, we may able to look at the possibility of using it to make...

Jumping gene helps explain immune system's abilities

...terial. "Jumping genes" essentially cut themselves out of the genetic material, and scientistshave suspec...a tiny loop.Unexpectedly, when Hermes is being cut out of the DNA, the leftover DNAalso forms a hairpin loop, temporarily doubling back on itself,postdocto...

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