Man and mouse share genome structures
...ption starting points of active genes, as they and others had seen earlier in the yeast. Unexpectedly, they also found tags idling over regions near genes. The researchers think these sites have important regulatory functions, because the methylation patterns are similar in comparable portions of the mouse ...It's not all genetic: Common epigenetic problem doubles cancer risk in mice
...oss of imprinting" of IGF2. Although Feinberg and others have already noted an association between loss of imprinting of IGF2 and colon cancer in people, the current experiments were designed to find out whether the loss of imprinting is involved in cancer's development or just in its progression. "Most r...Neuronal 'traffic jam' marks early Alzheimer's disease
...eurons. In studies with fruit flies, Goldstein and others had observed that overexpression of the gene for a key protein that underlies Alzheimer's pathology, called beta amyloid precursor protein (beta-APP), triggers defects in axonal transport. A defective version of beta-APP is cleaved to form an aberran...Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine
...nt. Scientists, including Drs. Chiorazzi, Rai and others at North Shore-LIJ, as well as other research groups in Bethesda, MD, San Diego, CA, and Barcelona, Spain, have identified genetic and protein markers that can predict whether a CLL patient will follow the benign or aggressive course. Some markers ar...Another Look Finds Promising Proteomics Test is Not Biologically Plausible
...l cancers before symptoms appear, but Baggerly and others maintain that the promise of this emerging field o...misdiagnosed three healthy individuals. But among others who subsequently tested the study’s data for reproducibility were Baggerly and his colleagues (Kevin......l cancers before symptoms appear, but Baggerly and others maintain that the promise of this emerging field o...misdiagnosed three healthy individuals. But among others who subsequently tested the study’s data for reproducibility were Baggerly and his colleagues (Kevin...Cracking the olfactory code in bees
...l cancers before symptoms appear, but Baggerly and others maintain that the promise of this emerging field o...misdiagnosed three healthy individuals. But among others who subsequently tested the study’s data for reproducibility were Baggerly and his colleagues (Kevin...Signaling protein builds bigger, better bones in mice
...l cancers before symptoms appear, but Baggerly and others maintain that the promise of this emerging field o...misdiagnosed three healthy individuals. But among others who subsequently tested the study’s data for reproducibility were Baggerly and his colleagues (Kevin...Newly discovered virus linked to childhood lung disorders and Kawasaki disease
...s andKawasaki disease will require confirmation by others in larger futureinvestigations....New Technique for Tracking Gene Regulators
...he pieces that have CREBattached, and wash all the others away. Scientists can use traditionalgene-sequencing methods to decipher the sequence of A, T, G, and C onthese fragments and then locate their original positions on the genome,but it is a slow and somewhat expensive process. Other methods, such asmat...Imaging Lymph Nodes with Nanoparticles
...hese methods have problems; someare very invasive, others are very time consuming, and none arecompletely reliable.However in one of the more exciting crossovers from chemistry intomedicine, researchers have developed nanoparticles to improve thediagnostic accuracy of MRI. The nanoparticles contain a centra...NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis
...ystem--when one response fails to fight infection, others step in." The study was also conducted at NYU, by a post-doctoral fellow, Mark Trottier, Jr., PhD, now at Michigan State, and Beth Palian, currently a doctoral student at the University of Southern California. Recently, the West Nile virus has been......cted that they might be related. Today, Smith and others have traced the succession of events that lead to ... whales might communicate across oceans. Clark and others have confirmed and expanded upon Roger Payne’s early work. Today Payne is pioneering a new frontier ...Experiments provide proof of how traveling in groups protects insects
...es nowadays, Mormon crickets just cost farmers and others a lot of money, but in parts of Africa and elsewhere, locusts can cause widespread famine because they consume crops, and the people there sometimes have nothing else to eat." ...Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease
... Stuart Schreiber; Michael Kamal, Eric Lander, and others at the Broad Institute; and their colleagues from Affymetrix, a California technology company. The analysis shows a striking and surprising exception in the way some critical genes are activated by the protein packaging. These proteins act like spoo...Weill Cornell Research Reveals Secrets Of Trafficking Within Cells
... that brain alive. Every one of these cells -- and others throughout the body -- depends on an internal process called endocytosis to keep the flow of cellular nutrients and information healthy and strong. It's an incredibly important life process, and now researchers at Weill Medical College of Cornell Un...Experiments provide proof of how traveling in groups protects insects
...es nowadays, Mormon crickets just cost farmers and others a lot of money, but in parts of Africa and elsewhere, locusts can cause widespread famine because they consume crops, and the people there sometimes have nothing else to eat." ...Taking Aim With Nanoparticle PEBBLEs
...ome to enhance their visibility on MRI images, and others to deliver a deadly cargo to cancer cells when triggered by exposure to light. Unlike chemotherapy drugs that attack tumors by invading cancer cells and disrupting their DNA, PEBBLEs never enter the cells they target. Instead, they attach to the out...Scientists identify genetic pathways essential to RNA interference
...lved with the packaging and processing of RNA, but others may be involved with the regulation of DNA itself, including the repair of DNA damage. "These new steps indicate there is more to RNAi than RNA destruction," says Kim. "And the connection to DNA damage pathways, which was totally unexpected, suggests...An entropy-based gene selection method for cancer classification using microarray data
...the results obtained were compared to work done by others using the same data sets. This study presents an entropy-based iterative algorithm for selecting genes from microarray data that are able to classify various cancer sub-types with high accuracy. In addition, the feature set obtained is very compact,...