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Tag: "orphan" at biology news

Beyond lithium for bipolar disorder

...igation of PACAP signaling in the brain and of the orphan receptor GPR88 as potential new targets in bipolar disorder." Philip E. Brandish, Ming Su, Daniel J. Holder, Paul Hodor, John Szumiloski, Robert R. Kleinhanz, Jaime E. Forbes, Mollie E. McWhorter, Sven J. Duenwald, Mark L. Parrish, Sang Na, Yuan Liu...

Free HIV tests cheaper than charging when goal is preventing AIDS

...sed case, counseling and information about HIV and orphan care and assistance. "They are a remarkable group of women doing the hard work of taking care of AIDS patients for the long-term. They asked us to provide an HIV testing program as a means of promoting behavioral changes, and that's really the gene...

New gene reduces retinal degeneration in fruit flies

... after the novel Lazarillo de Tormes, in which the orphan boy Làzaro helps a blind man see. Of the molecules known to control TRP channels, a key player is diacylglycerol, known as DAG. DAG is known to be made by a well-studied biochemical pathway. The researchers found that Lazaro provides a second way to...

Vaccine for brain tumors shows promising results

... therapy. Vitespen has been granted fast track and orphan drug designations from the Food and Drug Administration in both metastatic melanoma (skin cancer) and renal cell carcinoma (kidney cancer). The UCSF clinical trial is a phase1/2 study designed to establish the feasibility, safety and preliminary ...

Moonlighting enzyme linked to neurodegenerative disease

...disease of children and teens and is considered an orphan disease by the National Institutes of Health because of its rarity -- affecting one in 40,000. It is associated with a deficiency of frataxin, a protein that balances iron in mitochondria, which are the structures that convert nutrients into energy f...

UCSF brain tumor vaccine trial shows promising results

... therapy. Vitespen has been granted fast-track and orphan drug designations from the Food and Drug Administration for both metastatic melanoma (skin cancer) and renal cell carcinoma (kidney cancer). Reviewing the presentation at AANS, Henry Brem, MD, director of neurosurgery at the Johns Hopkins Medical...

Insomnia drug can improve brain function

...eneficial drugs, especially in the case of rare or orphan diseases. ...

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