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Tag: "organs" at biology news

A little telomerase isn't enough

...erely shortened telomeres and exhibited failure of organs that have high turnover of their cells -- the bone marrow and intestine among them. "We thought there might be some relationship between telomerase, telomere length and the survival of stem cells, but it was really exciting to see it," says Greider....

Pillows - a hot bed of fungal spores

...lungs and sinuses, although it can spread to other organs such as the brain, and is becoming increasingly common across other patient groups. It is very difficult to treat, and as many as 1 in 25 patients who die in modern European teaching hospitals have the disease. Immuno-compromised patients such as...

Polymer gel can block toxic leakage problem in gene therapy

...e of the viral particles were transported to other organs than were retained within the tumors. And most of the errant viruses ended up in the liver, where the gene therapy protein products could cause cell death. Moreover, most viruses escaped from their intended tumor targets during the first 10 minutes. ...

Max Planck researchers make a breakthrough in plant stem cell research

Totipotent stem cells allow plants to build new organs throughout their whole life. But it has been unclear how hormones and genetic factors work together to prevent plants from having growth that is either stunted, or uncontrolled and tumor-like. Scientists from the Max Planck Institute for Developmenta...

Cells from amniotic fluid used to tissue-engineer a new trachea

... investigating the idea of growing new tissues and organs for these tiny patients for eight years. Since the...le is large enough, the stomach and other visceral organs can end up in the chest cavity, crowding the lungs and stunting their growth. Using mesenchymal stem...

Cancer support cells may evolve, fuel tumor growth, study shows

...ting connective tissue that forms the framework of organs such as the breast, colon and prostate. They also are found in the tumor's blood vessels, or its vasculature. "Basically, virtually all the studies on genetic changes or changes in gene expression have focused on the cancer cell, on events within th...

USC researchers track down the stem cells that create feathers

...earning about is how stem cells are assembled into organs in nature. In this way, we can take advantage of t...e applied to help human stem cells and adult human organs to regenerate-and regenerate properly." ...

New evidence supports century-old theory of cancer spread

... the ability to migrate to lymph nodes and distant organs and to form a new blood supply. Our data indicate that they do this by hybridizing with macrophages," said lead author John Pawelek, research affiliate in the Department of Dermatology at Yale School of Medicine and a member of Yale Cancer Center. ...

Forgotten by evolution?

...ical of stem cells are being increasingly found in organs like the liver, brain, and muscles, scientists are beginning to assume that these cells play a role in repairing organs. Researchers from the Max Planck Institute for Heart and Lung Research in Bad Nauheim, Germany have now demonstrated, in a study p...

Scientists directly view immune cells interacting to avert autoimmunity

...ese physical interactions experimentally in living organs or even in cell cultures has been impossible before now, the scientists note. Their long-term aim is to use such imaging to diagnose immune diseases such as type 1 diabetes, and to further develop therapies that act at the level of T cell interaction...

MicroRNA may have fail-safe role in limb development

...sage into proteins - the building blocks of cells, organs and all of the various systems of the body. Unnoticed next to the main ingredients, microRNAs were considered to be "junk" DNA, leftovers from millions of years of evolution. More recently, this genetic material is suspected to be part of an intrica...

Antibacterial coatings cut infection rates

...ible for them to break away and travel into remote organs such as the brain or liver," Professor Griesser said. UniSA PhD student in applied science (minerals and materials), Sameer Al-Bataineh, has developed a fundamental understanding of the antibacterial coatings and how to make them. Using model substr...

Source of crucial immune cell in the skin discovered

...rder, large numbers of Langerhans cells infiltrate organs and tissues throughout the body. So, targeting the pathway by which these cells are formed could lead to new therapies to help children who now face the possibility of lifelong complications. "It is known that Csf-1 levels are elevated in patients ...

Swiss researchers develop all-in-one remote control gene expression tool

...use in stem cells, embryonic cells and tissues and organs that are amenable to genetic transduction. "It's a flexible way to regulate the expression of genes in a cell," says EPFL professor Didier Trono. "The lentiviral vector integrates in an irreversible fashion into the cell and is then part of its gene...

Technique makes it easier to see mouse embryo in all its glory

...omputational methods are applied to analyze embryo organs for defects. "From the moment of conception, the mice under study are genetically programmed to develop tumors," Dr. Keller said. "Intentional disruption of specific genes can cause birth defects in the same mice, which teaches us important lesson...

Pleasing plant shapes explained by new computer model

...eve phyllotaxis ?the unique arrangement of lateral organs around a central axis that results in the spiral patterns seen in most plants ?beginning at the molecular-level. "Biologists have many theories about why phyllotaxis exists but have always wondered how it happens," said Smith. "This model is excitin...

Marine mammals are on the frontline of failing ocean health

...sociated with bone and renal disease) is higher in organs of mammals with invertebrate-based diets. "The issue is to understand how pollutants are transferred through the ocean food web to consumers, both humans and animals," says Peggy Krahn of the NOAA. "Until we understand this, we can't start to s...

Darkness unveils vital metabolic fuel switch between sugar and fat

...By switching the primary source of energy in other organs from glucose to fat, 5'-AMP conserves glucose for brain function, the paper notes. "5'-AMP is a pivotal metabolic signal whose circulatory level determines the balance of the peripheral organ energy supply between glucose, glycogen and fat," the a...

UCSD biologists find new evidence for one-way evolution

...ltiple reappearances of complex traits after these organs were lost in ancestral species. The authors suggest that traditional methods for reconstructing the history of trait evolution may be inaccurate. Discovering irreversible change for this sexual system trait highlights the importance of considering g...

Forsyth scientists gain greater understanding of how embryos differentiate left from right

... early left/right patterning, the process by which organs locate themselves on the left or right side of the...owing an embryo to correctly position its internal organs along the left-right axis. Instead, their research showed a single asymmetry mechanism linking cilia...

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