organ 2 9

Tag: "organ" at biology news

How fish mend a broken heart

...lls can restore cells lost in the course of normal organ function or after minor injury but cannot regenerate after major damage or removal of structures. "It is believed that the capacity for regeneration is an ancestral condition that has occasionally been lost in the course of vertebrate evolution." P...

Single molecule extends fat mice lives by reversing gene pathways associated with disease in obese

... SD, HC, and HCR mice, and while not knowing which organ belonged to which mouse group, they looked for subtle changes in the abundance of fatty lesions, degeneration and inflammation. On a relative scale of 0-4, the assessment produced mean scores of 1.6 for the SD group, 3.2 for the HC group, and 1.2 fo...

Mechanical 'artificial hearts' can remove need for heart transplant by returning heart to normal

...larly the shortage of donor hearts and the risk of organ rejection. "This therapy has the potential to ease the pressure on the waiting list while also offering patients a better alternative to a donor heart ?their own, healthy heart," she added. Professor Sir Magdi Yacoub, from the Heart Science ...

How does your brain tell time?

...of physical changes to the brain’s cells helps the organ to monitor the passage of time. "The value of this research lies in understanding how the brain works," said Dean Buonomano, associate professor of neurobiology and psychiatry at the David Geffen School of Medicine at UCLA and a member of the univ...

Research project tackles 'regeneration' gap

...imple organisms that sustain successful tissue and organ regeneration following injury and disease, and the...tion needed in human organisms." Although human organ systems such as the liver are quite capable of regeneration, the brain has only a small quantity of ...

Many couples choose to donate surplus embryos for stem cell research

...n and people have traditionally been supportive of organ and tissue donation—the researchers believe that the results can be generalized to other countries. "We are convinced that if this type of personal interview and survey were carried out in the U.S.A., at least 50% of the couples would be willing ...

Protein may hold key to decreasing organ dysfunction rates in heart transplants

...the exact mechanisms of this injury concomitant to organ transplantation," notes Aigner, stressing the valu...rch to the development of new treatment options in organ transplantation. ...

Targeting tumors the natural way

...ing a potent immune response that caused immediate organ rejection. But true to natural cell recognition, the immune response occurs only when clusters of many alpha-Gal molecules are present for anti-Gal to bind with. Armed with this knowledge, Kiessling's group modified an agent known to bind tightly ...

Stanford scientists make major breakthrough in regenerative medicine

...uman regenerative medicine—a future where advanced organ damage can be repaired by the body itself. In the ...inciples of complex processes, such as healing and organ regeneration, on which new treatments are based. "The aim of biomedical science is to understand ...

Scientists discover new virus caused deaths of transplant recipients from single donor

...a small number of cases of disease transmission by organ transplantation, however, the newly discovered vir... using existing screening methods. Over 30,000 organ transplants are performed in the U.S. each year. Knowledge of the genetic sequence of this virus wi...

Statin plus cancer drug deliver combo punch to brain cancer cells

... pathway, long known to promote and guide cell and organ growth. Excessive growth is the chief characteristic of cancer. The investigators believe that blocking hedgehog with cyclopamine makes cancer cells more susceptible to lovastatin. Along with its cholesterol-clogging effects, lovastatin, sold unde...

Protein found to shield pancreatic cancer cells from self-destruction

...ls and in cancer that has spread from its original organ (metastasized). "In general, you rarely see overexpression of TG2 in a normal cell," says Kapil Mehta, Ph.D., professor in the M. D. Anderson Department of Experimental Therapeutics, who began 10 years ago studying TG2 as an inflammatory protein. ...

Penn researchers replace organ in adult mice using 'single-parent' stem cells

...me, successfully used them to repopulate a damaged organ with healthy cells in adult mice. Their findings...nt stem cells can proliferate normally in an adult organ and could provide a less controversial alternative to the therapeutic cloning of embryonic stem cell...

Researchers find hepatitis A and hepatitis C attack same protein to block immune defenses

...ver, until a victim’s only hope for survival is an organ transplant. According to researchers at the University of Texas Medical Branch at Galveston (UTMB), though, these two otherwise unrelated liver viruses have one important thing in common: a trick for avoiding destruction by the immune system. Both d...

Putting an old drug to a new use

...cess iron in various tissues, where it can lead to organ failure and even death if not treated before irrev...es after repeated blood transfusions and can cause organ failure over time. Günter Weiss, a clinician from the Innsbruck Medical University, and his collabor...

Tumor-suppressor gene is critical for placenta development

...tical role in the development of the placenta, the organ that controls nutrient and oxygen exchange between a mother and her fetus during pregnancy, and perhaps in miscarriages. Those conclusions come from a new study of the retinoblastoma (Rb) gene in mice. In humans, this gene, when mutated, raises the...

Penn study on olfactory nerve cells shows why we smell better when we sniff

... cavity. Synchronized Breathing The septal organ is only about 1 percent the size of the main olfactory epithelium and isn't shared by all mammals. Mice, for example, have a septal organ. Humans do not. But in this study, Ma's group found that 50 percent of the cells in the main olfactory epitheliu...

Liver regeneration may be simpler than previously thought

...s of what makes the liver so unique." Although organ regeneration has been observed in many animals, th...eneration behave as if they were part of a growing organ in an embryo. In other words, the cells act as if the liver is growing, as do other organs in a deve...

Soft-cell approach cuts animal tests

...ather than waiting for toxicity to be expressed as organ or organism failure many months or even years down the track from initial exposure. The application of in vitro methods could open new possibilities for toxicity testing of industrial chemicals, occupational and environmental contaminants, combus...

Discovery could lead to better control of hemorrhagic fever viruses

... a fact that may help account for the bleeding and organ damage caused by the viruses. TfR1 is also especially abundant on activated immune cells ?the very cells that mobilize to fight the viruses ?making them especially vulnerable to infection. "This may help explain why mortality is so high," says C...

1 2 3 4 5 6 7 8 9 10