Cardiologist's 'living chip' changes science of disease monitoring
...tion and stimulation of the surrounding tissues or organ systems, with the ability to detect changes. A change triggers a message to a wireless device to alert the patient early on about a problem. The patient can then contact their physician. For a patient with heart failure, for example, the biosensor ...Advance helps explain stem cell behavior
...s ultimately takes place during development of any organ or bodily system, the researchers said. The research identified the subset of genes involved in producing the various types of spinal cord cells ?there may be 10s to 100s of cell types just in the spinal cord. The cell types are created very quickly ...PNAS study reveals why organs fail following massive trauma
... to ten days after severe injury, causing multiple organ failure. That is one reason why trauma is the lead...ly on the problem of post-trauma immune system and organ failure, and has discovered several new biochemical pathways that play a central role, according to ...Beyond the book: Software automates access to brain atlases
...consult and compare data about a three-dimensional organ ?a rat, mouse, or human brain ?that is stacked up in hundreds or thousands of cross sectional views. Now researchers need to open a book to do this, which can slow things down. "Researchers need to be able to find a given segment immediately, and...Distinguishing friend from foe in the battle against cancer
...gs. Rapamycin, an immunosuppressant used to block organ rejection after transplants, also inactivates proteins stimulating cell division and in clinical trials has been combined with other drugs to halt cancer cell growth. But to cancer cells, rapamycin is both friend and foe. "Rapamycin is not as succe...Antibody extends life of mice with breast cancer
...ncer-cell growth that allow the cells to adhere to organ tissue, the research showed. Results of the research appeared in the November 2006 issue of the journal Neoplasia. Mice with breast-cancer tumors that received the antibody had a median survival time of 72 days, compared to 57 days for the anim...Scientists explore how complex organs develop from a simple bud
...ze how branching morphogenesis occurs in different organ systems in the same species. They also compare the...h and development of fetal stage organs can affect organ function after birth -- have important implications for human health. Two of the reviews in the Jo...Researchers identify new weapon to fight deadly bacterial sepsis
...oughout the body, often leading to heart and other organ failure and death. Even the best hospital intensiv...kened by HIV, using immune-suppressive therapy for organ and bone marrow transplants, and receiving high-dose chemotherapy for cancer. Young children and eld...Clue found to Epstein-Barr virus' ability to form and sustain tumors
...odgkin's lymphomas, lymphomas in AIDS patients and organ transplant recipients as well as nasopharyngeal carcinomas. The SMPH researchers, based at the McArdle Laboratory for Cancer Research, focused on a viral protein they had previously found to be necessary to keeping Burkitt's lymphoma cells alive and...PET imaging shows young smokers quick benefit of quitting
...easures metabolic activity and generates images of organ or tissue function?will continue to provide insight into coronary risk analysis and risk management (such as smoking cessation and lowering one's cholesterol)," he added. In the Hokkaido University study, researchers examined the effects of smokin...How mammals fuel milk production may have implications for cancer
... of cells,?Chodosh said. “The breast is an unusual organ that’s essentially a synthetic factory for milk. There’s nothing else like it.? During a typical 21-day course of lactation, a mouse will produce its entire body weight in lipid as well as three times its total body weight in milk, which consists ...Intravenous gene therapy protects normal tissue of mice during whole-body radiation
...e extremely damaging to cells, tissues, organs and organ systems," said Joel S. Greenberger, M.D., professor and chairman department of radiation oncology, University of Pittsburgh School of Medicine. "In previous studies, we demonstrated that gene therapy can be both swallowed in pill form and inhaled thr...An AIDS-related virus tricks cells to become tumors, new Penn study finds
...tients and those who are immune suppressed such as organ transplant patients are at high risk for developing Kaposi's sarcoma and another cancer called primary effusion lymphoma. The study describes how a KSHV-encoded protein, called latency-associated nuclear antigen, or LANA, tricks the cell into des...New findings could lead to vaccine for severe malaria
.... This causes the red blood cells to accumulate in organ capillaries, and gives rise to life-threatening symptoms. Adults who have been infected several times can become partly immune as their defence system gradually starts to recognise the parasite's proteins. When the placenta is formed, however, a new ...Vaccine-producing 'plant-factories'
...te recombinant proteins. The chloroplast is a cell organ with great capacity for storing proteins. However,...s. The newly discovered route connects the cell organ where the proteins are glycosylated, the reticulum, with the chloroplasts. This discovery signifies ...Living view in animals shows how cells decide to make proteins
...ng which silencers are active in a given tissue or organ will ultimately help scientists understand how exons are erroneously included or excluded in various disease processes," Bonano said. For example, a cell’s decision to include exon IIIb is critical because the exon’s presence or absence determine...Early-stage immune system control of HIV may depend on inherited factors
... that need to be matched as closely as possible in organ transplants, with perfect matches only possible between identical twins. Some studies have found that HIV patients with particular versions of HLA may be better able to control viral levels, but the diversity of HLA molecules ?each person may have u...Interaction between lymph and liver cells may affect immune response
...o migrate across the endothelium and interact with organ cells. Recent studies have shown that the liver is an exception in that liver cells may be able to act as APCs, activating T cells independently of the lymph system, a process which makes them less efficient. However, the question remains as to how ...New study aims to stop sepsis in its tracks
... the patient is quickly spiraling into multisystem organ failure. Starting resuscitation at this point may ...ure, and monitor cardiovascular function and other organ activity. It was developed several years ago by Emanuel Rivers, M.D., M.P.H., a researcher and physi......splant patients have the highest mortality rate of organ recipients, about 45% over five years, said lead i...teins that form a "biosignature" or "biomarker" of organ rejection from among the thousands of proteins that exist in the lung. Disease disturbs protein ...