UT Southwestern researchers find gene mutation that leads to 'broken hearts'
...ion and embryonic death." The heart is the first organ to form and function in the embryo. Abnormalities in the complex process of heart formation result in congenital heart defects, the most common birth defects in humans afflicting about 1 percent of newborns. Because the events of heart formation are ...Successful transplantation from pig embryos to mice
...oblems. Unfortunately, there are not nearly enough organ donors available for transplantation. Insulin-pro...Reisner and his team had shown that each embryonic organ has its own 'time window' during which the chances for successful transplantation are optimal. Prior...New stem-cell findings can help the body to cure itself
...n. Too few cells, on the other hand, can result in organ degeneration. It is therefore crucial that exactly the right number of cells are produced. As many serious disorders cause a reduction in the production of new cells, scientists are keen to develop drugs that stimulate the process, which in turn cou...Failure of 'scout cells' may lead to cancer in transplant patients
...e incidence of this cancer varies according to the organ transplanted, occurring in 1 to 2 percent of kidney transplant patients and in up to 20 percent of bone marrow and lung transplant patients. The disease usually arises within six months to a year after transplantation, and it can have a 70- to 80-per...Stimulation of the semicircular canals can artificially control human walking and balance
...the findings indicate that from the single sensory organ that signals the movement of the head, the brain makes instant complex "mathematical" calculations to discard the parts not important to balance or steering, such as the movements we make when looking around, and then transforms the remaining signal ...New compound reduces stroke damage
...tered to patients receiving transplants to prevent organ rejection. Dervatives of the drug are also commonly used in the treatment of autoimmune diseases. FK506 inhibits T-cell activation by binding to members of the FK506-binding protein (FKBP) family. Interestingly, FK506, and several molecules with simi...Researchers unveil strategy for creating actively-programmed anti-cancer molecules
...he bloodstream, anchor down in a distant tissue or organ to begin a new cancer-remains a critically important goal. The most recent figures from the Centers for Disease Control and Prevention indicate that more than 200,000 U.S. women are diagnosed with new cases of invasive breast cancer each year and tha...UCSD researchers develop 'smart petri dish'
... headed the research team. "Since the liver is the organ that cleans up the blood, liver cells are particularly susceptible when a toxin is introduced to the body. Pharmaceutical companies want to know early on the effect a drug has on the liver. But it's very expensive to screen every potential candidate ...Snakes' virtual glasses, leopard spots and all-optical transistors
... suggests that snakes shouldn't be able to use the organ to track prey very well because the pit aperture is large and the organ is not very deep. However, studies have shown that snakes can localize heat sources to a surprisingl...Smell of success for nanobiosensors
...ys, could lead to medical applications to diagnose organ failure, bacterial infections or diseases such as cancer being made commercially available within a few years, as well as devices that would have a major impact on other sectors. A major challenge of these new diagnostic tools lies in the establishme...Speeding the search for elusive chromosomal errors
...ths. Frequently the gene aberrations harm multiple organ systems. For example, patients with chromosome 22q11.2 deletion syndrome may have heart defects, impaired immunity and developmental delay. Deletions of several genes in Prader-Willi syndrome may cause obesity and mental retardation. To seek out min...Researcher studies, treats military with 'silent disease'
...thy tissue, blocking the flow of blood through the organ and preventing it from working as it should. Cirrhosis is the twelfth leading cause of death by disease, killing about 26,000 people each year, according to The National Digestive Diseases Information Clearinghouse Web site. Sjogren's clinic provid...Prion find points way to test for human 'mad cow' disease
...dt-Jakob disease (vCJD) via blood transfusions and organ transplants, the scientists suggest. Done in hamsters, the experiments are the first ever to biochemically detect the malformed proteins during the "silent phase" of the disease--just weeks after the animals were infected and months before they show...New study shows antibiotic may protect the heart
...rs studying rapamycin, an antibiotic used to boost organ survival in transplant patients, have found that the drug may protect the heart against tissue damage following acute heart attack. In the July issue of the Journal of Molecular and Cellular Cardiology, the official publication of the International...Medium is the message for stem cells in search of identities
...how does a batch of immature cells give rise to an organ as extraordinarily complex as the human brain? The findings, to be published this week in the Proceedings of the National Academy of Sciences, may one day help scientists create laboratory environments to grow specialized cells that can be transpl...Birds going extinct faster due to human activities
...how does a batch of immature cells give rise to an organ as extraordinarily complex as the human brain? The findings, to be published this week in the Proceedings of the National Academy of Sciences, may one day help scientists create laboratory environments to grow specialized cells that can be transpl...MUHC announces a transplant first in Quebec
...lth care professionals. The MUHC conducts the most organ transplants in Quebec and has the most comprehensi...tation, allowing us to successfully offer combined organ transplants within one institution." The world's first heart transplant was conducted less than for...Healing the heart with bone marrow cells
..., mechanical assistance devices, drug therapy, and organ transplantation, more than half of patients with congestive heart failure die within five years of initial diagnosis. "Cardiovascular diseases are the most important cause of mortality in Canada and the western world," said Dr. Ren-Ke Li, scientist ...OHSU study says stem cell 'fusion' occurs in tumors
...ds stem cells with bone marrow cells to regenerate organ tissue. Scientists in the OHSU School of Medicine found that transplanted cells derived from adult bone marrow can fuse with intestinal stem cells of both normal and diseased tissue comprising the cellular lining of intestinal walls, known as the ep......, mechanical assistance devices, drug therapy, and organ transplantation, more than half of patients with congestive heart failure die within five years of initial diagnosis. "Cardiovascular diseases are the most important cause of mortality in Canada and the western world," said Dr. Ren-Ke Li, scientist ...