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Tag: "organ" at biology news

Portable cocaine sensor developed at UC Santa Barbara

...nosuppressant that has revolutionized the field of organ transplants, must be carefully monitored in a patient's blood to regulate the dosage. The test to check the ratio of a therapeutic dose versus a lethal dose is a process that takes six hours. With the new sensor, the blood level of the drug could be ...

3D ultrasound device poised to advance minimally invasive surgery

...ors could see the target lesion or a portion of an organ in a real-time three-dimensional scan," Smith said. "They would have the option of viewing the tissue in three perpendicular cross-sectional slices simultaneously or in the same way a camera would see it ? except that a camera can't see through blood...

Rare Tibetan antelope listed as endangered

...ors could see the target lesion or a portion of an organ in a real-time three-dimensional scan," Smith said. "They would have the option of viewing the tissue in three perpendicular cross-sectional slices simultaneously or in the same way a camera would see it ? except that a camera can't see through blood...

Carnegie Mellon develops non-invasive technique to detect transplant rejection at cellular level

...ltrate a transplanted heart in the early stages of organ rejection. This pre-clinical advance, described in...the preferred clinical approach to treat end-stage organ failure, but transplant patients face a lifetime of immunosuppressive therapy and the risk of losing...

Powerful new tool for studying brain development

..., is one of the largest gene expression maps of an organ ever developed, according to the St. Jude researchers. They say the map will likely help scientists discover the genetic origins of brain cancers, which could speed development of novel drugs to treat them. The continual updating and completion of t...

Screening blood for West Nile virus

...ing with compromised immune systems (recipients of organ transplants, patients with HIV/AIDS, and others), the idea of creating a 'supersafe' pool of blood products that is reserved for people who are less able to fight off infections contracted through contaminated blood seems well worth considering. In...

New research demonstrates bone-marrow derived stem cells can reverse genetic kidney disease

...ing basement membrane matrix defects and restoring organ function. Led by researchers at Beth Israel Deaconess Medical Center (BIDMC), the findings are described in the Proceedings of the National Academy of Sciences (PNAS), which appears on-line the week of April 24, 2006. Symptoms of Alport syndrome, ...

Darkness unveils vital metabolic fuel switch between sugar and fat

...ory level determines the balance of the peripheral organ energy supply between glucose, glycogen and fat," the authors conclude, raising the longer-term possibility of 5'-AMP-based therapies for obesity or type 2 diabetes. ...

Tool developed to silence genes in specific tissues using RNAi

...skin, or different parts of the brain, or whatever organ or tissue you are likely to want," Wilkinson says. "By swapping out either of these modules, you have the potential to silence any gene in any tissue you might want," he said. In their study, the researchers made a vector with a promoter specific fo...

Avian influenza virus in mammals spreads beyond the site of infection to other organ systems

...us membranes (throat, nasal, and rectal swabs) and organ systems (respiratory, digestive, nervous, cardiova...ion. Most interesting, virus spread throughout the organ systems with virus being found in respiratory and digestive tracts, liver, kidney, heart, brain, and...

Two NIH initiatives launch intensive efforts to find roots of common diseases

... for HIV/AIDS, heart disease and the prevention of organ rejection," said Martin Mackay, Ph.D., Senior Vice President Worldwide Research & Technology, Pfizer Research & Development. "But these advances have only scratched the surface of possible revolutionary approaches to treat and cure diseases. ...

Cyclosporine inhibits hepatitis C virus in vitro

...fter liver transplantation, often damaging the new organ and rendering patients ineligible for retransplantation. To address this problem, patients with hepatitis C often undergo interferon-ribavirin combination therapy after receiving a liver transplant in hopes of a sustained virologic response. At the s...

Mice with glowing hearts shed light on how hearts develop

...he heart forms. In mammals, the heart is the first organ to function and starts beating prior to its full development. "We knew that the heart starts to pump at around 9.5 days," said Kotlikoff. By day 10.5, there are only two chambers (rather than four chambers in an adult mammal): an atrium on top and ...

Convergent evolution of molecules in electric fish

... both genes in the muscle, but as the new electric organ was evolving, the sodium channel--by being lost from the muscle--became devoted to the electric organ," Zakon says. "So two times, independently, the gene has been 'lost' from the muscle. It's no longer able to turn-on in a cell that for millions of ...

'Scent of a woman' tells male redback spiders to find a mate

...t a sperm plug -- a small part of their copulatory organ that stays inside the female -- that prevents any future males from successfully fertilizing her eggs, meaning that males have to mate with a virgin to maximize their reproductive success. "On the one hand, they want to provision themselves to survi...

Anti-inflammatory drug's potentially deadly side effect found to be rare

... brain and cause PML. That includes AIDS patients, organ transplant patients and patients with blood-related malignancies such as leukemia. And even in those patients it's still rare--we've seen about 50 cases over the last decade at Washington University School of Medicine." In patients with PML, the vir...

Researches discover gene critical for protection against septic-shock-induced death

...ardial injury, acute respiratory failure, multiple organ failure or death. Controlling inflammation is thus a central focus of treating sepsis. Researchers have been hunting for novel host genes that regulate inflammation as potential targets for the next generation of sepsis therapies. The incidence of se...

Gene discovery may shed light on kidney disease

...lies. "While Alagille syndrome is relatively rare, organ diseases are not rare, and our findings suggest that genes on this biological pathway may have a broader role in kidney disorders," said study leader Nancy B. Spinner, Ph.D., a geneticist at The Children's Hospital of Philadelphia. The study appear...

Study finds how organs monitor themselves during early development

...y aren't well understood. Feedback loops enable an organ such as the liver to detect if it is injured, asce..., control each other and function together when an organ grows," she says. In the human ovary for example, a follicle ripens every month. Without the somatic...

U of M researchers discover genetic key to treating deadly fungal infections

...ed (by AIDS, chemotherapy, or drugs for surgery or organ transplantation) it can produce deadly, systemic infections, causing death in 30 to 50 percent of cases. Premature babies, whose immune systems are immature, are also at risk. Led by Judith Berman, professor of genetics, cell biology and developm...

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