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Tag: "organ" at biology news

MUHC scientists describe genetic resistance to rampant virus

...in those with a compromised immune system, such as organ transplant recipients, newborns and persons infected with human immunodeficiency virus (HIV). Dr. Vidal believes her groundbreaking discovery increases the likelihood that therapies will be developed to fight CMV. ...

NIAID begins clinical trial of West Nile virus vaccine

...rus also can be spread through blood transfusions, organ transplants and breastfeeding, as well as from mother to child during pregnancy. Most people experience no symptoms or only mild symptoms, such as fever, headache and body aches; more serious cases can lead to infections of the brain and nervous syst...

Doctors closer to using gene analysis to help trauma patients

...on who go on to develop complications that lead to organ failure and death, which is the most common cause ...ath after traumatic injury ?sepsis and multisystem organ failure. So the goal is to use functional genomics as a tool to identify those patients who, after s...

Protein prevents detrimental immune effects of bacterial sepsis

.... Higher levels of markers of inflammation, and of organ injury, were measured in annexin 1 deficient animals. Altogether, these findings implied that the protective effects of the annexin 1 pathway were activated in the first few hours following toxin administration. In fact, when annexin 1 knockout mice ...

Disease progression model of pancreatic cancer developed by Penn researchers

...son. The frequency of metastases to these various organ sites was also highly similar to that seen in humans. In human patients, 60 to 80 percent develop metastases to the liver; and 50 to 60 percent develop metastases to the lungs. In the genetically modified animals, 63 percent displayed liver metastase...

Gov't Creates Gene Database of Normal Human Tissues

... resource for the research community." The normal organ database uses a technology known as gene expressio...ts as those done within a single lab**. The normal organ database takes that one step further, enabling scientists and clinicians to compare the gene express...

Precise Timing Enabled Pig-to-rat Transplants To Cure Diabetes

...m cells and other embryonic cell clusters known as organ primordia. Unlike embryonic stem cells, which can ...ansplants had suggested that a second unsuccessful organ transplant can "wake up" the immune system and lead it to reject an earlier successful transplant of...

A probe, not an echo

...he Viterbi School, presented HUTT images of animal organ tissue in San Diego at the 28th International Acoustical Imaging Symposium, held March 20-23. According to Marmarelis, HUTT offers nearly order-of-magnitude improvement in resolution of structures in soft tissue (i.e., 0.4 mm, compared to 2 mm for t...

Circulating stem cells play small role in lung repair

...on in this area," Zander said. "It's a challenging organ to study because the air-tissue interfaces make it difficult to separate different cell types." Applying advanced research techniques that previously had been used to analyze liver and bone marrow transplant recipients, the team found that nine of 2...

Candida albicans Genome Fully Annotated

...on in this area," Zander said. "It's a challenging organ to study because the air-tissue interfaces make it difficult to separate different cell types." Applying advanced research techniques that previously had been used to analyze liver and bone marrow transplant recipients, the team found that nine of 2...

Certain fish have a special mating preference

... genitalia, who lose out because the size of their organ slows them down, making them ripe for capture by l...ary sexual trait ?which is the actual reproductive organ itself, simply meant to transfer sperm. Historically, genitalia were not believed to be subject to s...

Stem cell therapy successfully treats heart attack in animals

... have the same potential to develop into different organ tissues, as do embryonic stem cells, whose use is more controversial. ...

IMF Launches World’s First DNA Database for Myeloma Patients

... genitalia, who lose out because the size of their organ slows them down, making them ripe for capture by l...ary sexual trait ?which is the actual reproductive organ itself, simply meant to transfer sperm. Historically, genitalia were not believed to be subject to s...

Study: Well-known protein helps stem cells become secretory cells

...etion in the salivary gland, the largest glandular organ in the fruit fly embryo, approximately six years ago. In humans and in fruit flies, the gland secretes saliva, a fluid containing water, mucus, electrolytes, and food-dissolving enzymes, into the mouth, and is important to the digestive system. In t...

Researchers grow stem cells from human skin

...tient's own skin, there would not be problems with organ or tissue rejection." The research team grew mesenchymal stem cells, a type of stem cell normally found in bone marrow. Using tissue samples from 15 donors who had routine circumcisions, the scientists were able to isolate single stem cells, which t...

One hit of crystal meth causes birth defects

...c stage through the later fetal period, times when organ structures and mental functions develop. "People usually think the last trimester of pregnancy is when developing brain function is most susceptible to damage, but in this case the brain is also affected by methamphetamine even in the earlier embryo...

New tool reveals secrets of migrating cells

...to the native environment while keeping the intact organ alive and make movies of migrating cells." With two-photon imaging, Witt and Robey identified thymus cells they dubbed beeliners moving nearly two centimeters - almost an inch - per hour, which is fast in the realm of cell movement. They think that ...

Discoveries by UAB and Florida scientists may help transplanted organs survive longer

...ientists may have found a way to dramatically slow organ transplant rejection by as much as several years. ...e principal problems for kidney transplantation is organ availability," said Mark A. Atkinson, Ph.D., a study co-author and director of the Center for Immuno...

New type of rejection blocker protects kidneys after transplant

...ing the immune system's reaction to a transplanted organ without hampering the body's ability to fight dise...eir promise, they will usher in a new paradigm for organ transplantation," Vincenti said. Instead of sending patients home with a collection of medications t...

Insulin pulses keep the liver lean

...wly discovered role for insulin may explain how an organ frequently flooded with the fat-building hormone normally stays trim and also suggests new dietary strategies and treatments to avoid fatty liver, a growing healthcare epidemic, said the researchers. Insulin produced by the pancreas allows cells to ...

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